Mutated cells mediate distinct inflammatory responses in clonal hematopoiesis JB Heimlich, P Bhat, AC Parker, MT Jenkins, C Vlasschaert, J Ulloa, ... bioRxiv, 2022 | 5 | 2022 |
The role of migration in mutant dynamics in fragmented populations J Kreger, D Brown, NL Komarova, D Wodarz, J Pritchard Journal of Evolutionary Biology 36 (2), 444-460, 2023 | 4 | 2023 |
DNMT3A R882H Exhibits Greater Inflammatory Potential Than R882C in Primary Hematopoietic Stem and Progenitor Cell Knock-in Model and Population Data AJ Silver, DJ Brown, C Vlasschaert, P Bhat, F Puddu, JC Van Amburg, ... Blood 142, 815, 2023 | 2 | 2023 |
Lactate utilization enables metabolic escape to confer resistance to BET inhibition in acute myeloid leukemia AJ Monteith, HE Ramsey, AJ Silver, D Brown, D Greenwood, BN Smith, ... Cancer Research, 2024 | 1 | 2024 |
The role of migration in mutant evolution in fragmented populations J Kreger, D Brown, NL Komarova, D Wodarz, J Pritchard bioRxiv, 2021.06. 09.447669, 2021 | 1 | 2021 |
Clonal Hematopoiesis and Inflammation in the VasculaturE (CHIVE): a prospective, longitudinal clonal hematopoiesis cohort and biorepository ML Shannon, JB Heimlich, S Olson, A Debevec, Z Copeland, A Kishtagari, ... Blood Advances, 2024 | | 2024 |
Clonal Hematopoiesis and Inflammation in the VasculaturE (CHIVE): a prospective, longitudinal cohort and biorepository ML Shannon, JB Heimlich, S Olson, A Debevec, Z Copeland, A Kishtagari, ... Blood Advances, bloodadvances. 2023011510, 2024 | | 2024 |
Multiomic Profiling of Human Clonal Hematopoiesis Reveals Genotype and Cell-Specific Inflammatory Pathway Activation JB Heimlich, P Bhat, AC Parker, MT Jenkins, C Vlasschaert, J Ulloa, ... Blood Advances, 2024 | | 2024 |
Repair of leukemia-associated single nucleotide variants via interallelic gene conversion AJ Silver, DJ Brown, SD Olmstead, JM Watke, AE Gorska, L Tanner, ... bioRxiv, 2024.04. 16.587991, 2024 | | 2024 |
Clonal Hematopoiesis and Inflammation in the Vasculature (CHIVE), a Prospective, Longitudinal Clonal Hematopoiesis Cohort and Biorepository J Heimlich, M Shannon, S Olson, AJ Silver, A Debevec, Z Copeland, ... Blood 142, 5594, 2023 | | 2023 |
Excessive concentrations of kinase inhibitors in translational studies impede effective drug repurposing C Liu, SM Leighow, K McIlroy, M Lu, KA Dennis, K Abello, DJ Brown, ... Cell Reports Medicine 4 (10), 2023 | | 2023 |
The role of migration in mutant dynamics in fragmented populations. D Wodarz, J Pritchard, J Kreger, D Brown, N Komarova Journal of Evolutionary Biology 36 (2), 2023 | | 2023 |
Combined Single-Cell Transcriptomics and Mitochondrial Lineage Tracing Identify IL-6 Signaling Responses in TET2 Clonal Hematopoiesis of Indeterminate Potential P Bhat, JB Heimlich, A Parker, MT Jenkins, CR Potts, J Ulloa, AJ Silver, ... Blood 140 (Supplement 1), 2891-2892, 2022 | | 2022 |
Lactate Utilization Provides a Metabolic Escape to Resist the Antileukemic Activity of BET Inhibition in Acute Myeloid Leukemia AJ Monteith, HE Ramsey, D Greenwood, MP Arrate, L Fuller, AE Gorska, ... Blood 140 (Supplement 1), 8709-8710, 2022 | | 2022 |
Primary HSPC-Derived Monocytes with DNMT3A p. R882H Exhibit Activated Myeloid Cell Gene Signatures AJ Silver, DJ Brown, MP Arrate, Y Wang, MA Fischer, P Bhat, JB Heimlich, ... Blood 140 (Supplement 1), 2885-2886, 2022 | | 2022 |