| Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53 P Di Lello, LMM Jenkins, TN Jones, BD Nguyen, T Hara, H Yamaguchi, ... Molecular cell 22 (6), 731-740, 2006 | 240 | 2006 |
| Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy I Ullah, J Prévost, MS Ladinsky, H Stone, M Lu, SP Anand, ... Immunity 54 (9), 2143-2158. e15, 2021 | 175 | 2021 |
| Sending proteins to dense core secretory granules: still a lot to sort out JD Dikeakos, TL Reudelhuber The Journal of cell biology 177 (2), 191-196, 2007 | 151 | 2007 |
| Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2 R Gasser, M Cloutier, J Prévost, C Fink, É Ducas, S Ding, N Dussault, ... Cell reports 34 (9), 2021 | 103 | 2021 |
| Small Molecule Inhibition of HIV-1–Induced MHC-I Down-Regulation Identifies a Temporally Regulated Switch in Nef Action JD Dikeakos, KM Atkins, L Thomas, L Emert-Sedlak, IJL Byeon, J Jung, ... Molecular biology of the cell 21 (19), 3279-3292, 2010 | 89 | 2010 |
| An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I JD Dikeakos, L Thomas, G Kwon, J Elferich, U Shinde, G Thomas Molecular biology of the cell 23 (11), 2184-2197, 2012 | 81 | 2012 |
| HIV-1 Nef: a master manipulator of the membrane trafficking machinery mediating immune evasion EN Pawlak, JD Dikeakos Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (4), 733-741, 2015 | 80 | 2015 |
| HIV-1 Nef sequesters MHC-I intracellularly by targeting early stages of endocytosis and recycling BS Dirk, EN Pawlak, AL Johnson, LR Van Nynatten, RA Jacob, B Heit, ... Scientific reports 6 (1), 37021, 2016 | 78 | 2016 |
| The multifunctional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell-cycle arrest KM Atkins, LL Thomas, J Barroso-Gonzalez, L Thomas, S Auclair, J Yin, ... Cell reports 8 (5), 1545-1557, 2014 | 71 | 2014 |
| KIM-1/TIM-1 is a Receptor for SARS-CoV-2 in Lung and Kidney Y Mori, C Fink, T Ichimura, K Sako, M Mori, NN Lee, P Aschauer, ... MedRxiv, 2020.09. 16.20190694, 2020 | 70 | 2020 |
| Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster … NW Werneburg, SF Bronk, ME Guicciardi, L Thomas, JD Dikeakos, ... Journal of Biological Chemistry 287 (29), 24427-24437, 2012 | 65 | 2012 |
| Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease JD Dikeakos, P Di Lello, MJ Lacombe, R Ghirlando, P Legault, ... Proceedings of the National Academy of Sciences 106 (18), 7408-7413, 2009 | 49 | 2009 |
| MIiSR: molecular interactions in super-resolution imaging enables the analysis of protein interactions, dynamics and formation of multi-protein structures FA Caetano, BS Dirk, JHK Tam, PC Cavanagh, M Goiko, SSG Ferguson, ... PLoS computational biology 11 (12), e1004634, 2015 | 44 | 2015 |
| PC1/3, PC2 and PC5/6A are targeted to dense core secretory granules by a common mechanism JD Dikeakos, C Mercure, MJ Lacombe, NG Seidah, TL Reudelhuber The FEBS journal 274 (16), 4094-4102, 2007 | 38 | 2007 |
| A hydrophobic patch in a charged α-helix is sufficient to target proteins to dense core secretory granules JD Dikeakos, MJ Lacombe, C Mercure, M Mireuta, TL Reudelhuber Journal of Biological Chemistry 282 (2), 1136-1143, 2007 | 36 | 2007 |
| Interferon-induced HERC5 is evolving under positive selection and inhibits HIV-1 particle production by a novel mechanism targeting Rev/RRE-dependent RNA nuclear export MW Woods, JG Tong, SK Tom, PA Szabo, PC Cavanagh, JD Dikeakos, ... Retrovirology 11, 1-17, 2014 | 34 | 2014 |
| Efferocytic defects in early atherosclerosis are driven by GATA2 overexpression in macrophages C Yin, AM Vrieze, M Rosoga, J Akingbasote, EN Pawlak, RA Jacob, J Hu, ... Frontiers in immunology 11, 594136, 2020 | 32 | 2020 |
| HIV-1 Vpu Downregulates Tim-3 from the Surface of Infected CD4+ T Cells J Prévost, CR Edgar, J Richard, SM Trothen, RA Jacob, MJ Mumby, ... Journal of Virology 94 (7), 10.1128/jvi. 01999-19, 2020 | 32 | 2020 |
| The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4+ T cells EN Pawlak, BS Dirk, RA Jacob, AL Johnson, JD Dikeakos Retrovirology 15, 1-22, 2018 | 32 | 2018 |
| Soluble CD93 is an apoptotic cell opsonin recognized by αxβ2 JWD Blackburn, DHC Lau, EY Liu, J Ellins, AM Vrieze, EN Pawlak, ... European Journal of Immunology 49 (4), 600-610, 2019 | 30 | 2019 |
