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| Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex RE Lawrence, SA Fromm, Y Fu, AL Yokom, DJ Kim, AM Thelen, ... Science 366 (6468), 971-977, 2019 | 147 | 2019 |
| Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation AL Yokom, SN Gates, ME Jackrel, KL Mack, M Su, J Shorter, ... Nature structural & molecular biology 23 (9), 830-837, 2016 | 117 | 2016 |
| ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer X Shi, AL Yokom, C Wang, LN Young, RJ Youle, JH Hurley Journal of Cell Biology 219 (7), e201911047, 2020 | 83 | 2020 |
| Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy BG Horst, AL Yokom, DJ Rosenberg, KL Morris, M Hammel, JH Hurley, ... Elife 8, e50634, 2019 | 79 | 2019 |
| A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission TG Flower, Y Takahashi, A Hudait, K Rose, N Tjahjono, AJ Pak, ... Nature structural & molecular biology 27 (6), 570-580, 2020 | 64 | 2020 |
| The autophagy adaptor NDP52 and the FIP200 coiled-coil allosterically activate ULK1 complex membrane recruitment X Shi, C Chang, AL Yokom, LE Jensen, JH Hurley Elife 9, e59099, 2020 | 61 | 2020 |
| The full-length cytochrome P450 enzyme CYP102A1 dimerizes at its reductase domains and has flexible heme domains for efficient catalysis H Zhang, AL Yokom, S Cheng, M Su, PF Hollenberg, DR Southworth, ... Journal of Biological Chemistry 293 (20), 7727-7736, 2018 | 51 | 2018 |
| Architecture of the Nitric-oxide Synthase Holoenzyme Reveals Large Conformational Changes and a Calmodulin-driven Release of the FMN Domain*♦ AL Yokom, Y Morishima, M Lau, M Su, A Glukhova, Y Osawa, ... Journal of Biological Chemistry 289 (24), 16855-16865, 2014 | 50 | 2014 |
| Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy C Chang, X Shi, LE Jensen, AL Yokom, D Fracchiolla, S Martens, ... Science Advances 7 (17), eabg4922, 2021 | 49 | 2021 |
| Mining disaggregase sequence space to safely counter TDP-43, FUS, and α-synuclein proteotoxicity A Tariq, JB Lin, ME Jackrel, CD Hesketh, PJ Carman, KL Mack, ... Cell reports 28 (8), 2080-2095. e6, 2019 | 47 | 2019 |
| The same site on the integrase-binding domain of lens epithelium–derived growth factor is a therapeutic target for MLL leukemia and HIV MJ Murai, J Pollock, S He, H Miao, T Purohit, A Yokom, JL Hess, ... Blood, The Journal of the American Society of Hematology 124 (25), 3730-3737, 2014 | 43 | 2014 |
| Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation X Ren, TN Nguyen, WK Lam, CZ Buffalo, M Lazarou, AL Yokom, ... Science advances 9 (7), eadg2997, 2023 | 34 | 2023 |
| Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation RM Jansen, R Peruzzo, SA Fromm, AL Yokom, R Zoncu, JH Hurley Science advances 8 (37), eadd2926, 2022 | 24 | 2022 |
| Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1 AK Cada, MR Pavlin, JP Castillo, AB Tong, KP Larsen, X Ren, AL Yokom, ... Proceedings of the National Academy of Sciences 119 (29), e2204536119, 2022 | 17 | 2022 |
| Allosteric regulation of oligomerization by a B12 trafficking G-protein is corrupted in methylmalonic aciduria M Ruetz, GC Campanello, L McDevitt, AL Yokom, PK Yadav, D Watkins, ... Cell chemical biology 26 (7), 960-969. e4, 2019 | 15 | 2019 |
| Switch I-dependent allosteric signaling in a G-protein chaperone–B12 enzyme complex GC Campanello, M Lofgren, AL Yokom, DR Southworth, R Banerjee Journal of Biological Chemistry 292 (43), 17617-17625, 2017 | 15 | 2017 |
| Kinetic analysis of IgG antibodies to beta-amyloid oligomers with surface plasmon resonance AC Crisostomo, L Dang, JL Digambaranath, AC Klaver, DA Loeffler, ... Analytical biochemistry 481, 43-54, 2015 | 14 | 2015 |
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