| Target identification using drug affinity responsive target stability (DARTS) B Lomenick, R Hao, N Jonai, RM Chin, M Aghajan, S Warburton, J Wang, ... Proceedings of the National Academy of Sciences 106 (51), 21984-21989, 2009 | 950 | 2009 |
| The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR RM Chin, X Fu, MY Pai, L Vergnes, H Hwang, G Deng, S Diep, ... Nature 510 (7505), 397-401, 2014 | 647 | 2014 |
| COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness SF Heeringa, G Chernin, M Chaki, W Zhou, AJ Sloan, Z Ji, LX Xie, ... The Journal of clinical investigation 121 (5), 2013-2024, 2011 | 436 | 2011 |
| ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption S Ashraf, HY Gee, S Woerner, LX Xie, V Vega-Warner, S Lovric, H Fang, ... The Journal of clinical investigation 123 (12), 5179-5189, 2013 | 370 | 2013 |
| Endogenous synthesis of coenzyme Q in eukaryotes UPC Tran, CF Clarke Mitochondrion 7, S62-S71, 2007 | 312 | 2007 |
| Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q PL Larsen, CF Clarke Science 295 (5552), 120-123, 2002 | 304 | 2002 |
| A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants T Jonassen, PL Larsen, CF Clarke Proceedings of the National Academy of Sciences 98 (2), 421-426, 2001 | 242 | 2001 |
| The COQ7 Gene Encodes a Protein in Saccharomyces cerevisiae Necessary for Ubiquinone Biosynthesis (∗) BN Marbois, CF Clarke Journal of Biological Chemistry 271 (6), 2995-3004, 1996 | 240 | 1996 |
| Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis A Devarajan, N Bourquard, S Hama, M Navab, VR Grijalva, S Morvardi, ... Antioxidants & redox signaling 14 (3), 341-351, 2011 | 204 | 2011 |
| Enhanced sensitivity of ubiquinone-deficient mutants of Saccharomyces cerevisiae to products of autoxidized polyunsaturated fatty acids. TQ Do, JR Schultz, CF Clarke Proceedings of the National Academy of Sciences 93 (15), 7534-7539, 1996 | 199 | 1996 |
| A C-methyltransferase involved in both ubiquinone and menaquinone biosynthesis: isolation and identification of the Escherichia coli ubiE gene PT Lee, AY Hsu, HT Ha, CF Clarke Journal of bacteriology 179 (5), 1748-1754, 1997 | 191 | 1997 |
| A Regulated Response to Impaired Respiration Slows Behavioral Rates and Increases Lifespan in Caenorhabditis elegans D Cristina, M Cary, A Lunceford, C Clarke, C Kenyon PLoS genetics 5 (4), e1000450, 2009 | 180 | 2009 |
| Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis T Jonassen, M Proft, F Randez-Gil, JR Schultz, BN Marbois, KD Entian, ... Journal of biological chemistry 273 (6), 3351-3357, 1998 | 177 | 1998 |
| Molecular cloning and sequence of a cholesterol-repressible enzyme related to prenyltransferase in the isoprene biosynthetic pathway CF Clarke, RD Tanaka, K Svenson, M Wamsley, AM Fogelman, ... Molecular and cellular biology, 1987 | 165 | 1987 |
| Identification of Escherichia coli ubiB, a Gene Required for the First Monooxygenase Step in Ubiquinone Biosynthesis WW Poon, DE Davis, HT Ha, T Jonassen, PN Rather, CF Clarke Journal of bacteriology 182 (18), 5139-5146, 2000 | 159 | 2000 |
| A defect in Coenzyme Q biosynthesis is responsible for the respiratory deficiency in Saccharomyces cerevisiae abc1Mutants TQ Do, AY Hsu, T Jonassen, PT Lee, CF Clarke Journal of Biological Chemistry 276 (21), 18161-18168, 2001 | 156 | 2001 |
| Purification of Complexes of Nuclear Oncogene p53 with Rat and Escherichia coli Heat Shock Proteins: In Vitro Dissociation of hsc70 and dnaK from Murine p53 by … CF Clarke, K Cheng, AB Frey, R Stein, PW Hinds, AJ Levine Molecular and cellular biology 8 (3), 1206-1215, 1988 | 148 | 1988 |
| Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria MA Kiebish, X Han, H Cheng, A Lunceford, CF Clarke, H Moon, ... Journal of neurochemistry 106 (1), 299-312, 2008 | 143 | 2008 |
| Complementation of coq3 mutant yeast by mitochondrial targeting of the Escherichia coli UbiG polypeptide: evidence that UbiG catalyzes both O-methylation steps in ubiquinone … AY Hsu, WW Poon, JA Shepherd, DC Myles, CF Clarke Biochemistry 35 (30), 9797-9806, 1996 | 143 | 1996 |
| Coenzyme Q10 deficiencies: pathways in yeast and humans AM Awad, MC Bradley, L Fernández-del-Río, A Nag, HS Tsui, CF Clarke Essays in biochemistry 62 (3), 361-376, 2018 | 142 | 2018 |
Agape M AwadPhD from University of California, Los Angeles在 chem.ucla.edu 的电子邮件经过验证
