A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses V Härmä, J Virtanen, R Mäkelä, A Happonen, JP Mpindi, M Knuuttila, ... PloS one 5 (5), e10431, 2010 | 419 | 2010 |
Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells P Östling, SK Leivonen, A Aakula, P Kohonen, R Mäkelä, Z Hagman, ... Cancer research 71 (5), 1956-1967, 2011 | 319 | 2011 |
Loss of Pax5 promotes plasma cell differentiation KP Nera, P Kohonen, E Narvi, A Peippo, L Mustonen, P Terho, K Koskela, ... Immunity 24 (3), 283-293, 2006 | 297 | 2006 |
Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines SK Leivonen, R Mäkelä, P Östling, P Kohonen, S Haapa-Paananen, ... Oncogene 28 (44), 3926-3936, 2009 | 281 | 2009 |
Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis S Pollari, SM Käkönen, H Edgren, M Wolf, P Kohonen, H Sara, T Guise, ... Breast cancer research and treatment 125, 421-430, 2011 | 277 | 2011 |
High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth K Iljin, K Ketola, P Vainio, P Halonen, P Kohonen, V Fey, RC Grafström, ... Clinical Cancer Research 15 (19), 6070-6078, 2009 | 244 | 2009 |
Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme K Ovaska, M Laakso, S Haapa-Paananen, R Louhimo, P Chen, ... Genome medicine 2, 1-12, 2010 | 229 | 2010 |
Androgen regulation of micro‐RNAs in prostate cancer KK Waltering, KP Porkka, SE Jalava, A Urbanucci, PJ Kohonen, ... The Prostate 71 (6), 604-614, 2011 | 195 | 2011 |
Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer P Vainio, S Gupta, K Ketola, T Mirtti, JP Mpindi, P Kohonen, V Fey, ... The American journal of pathology 178 (2), 525-536, 2011 | 172 | 2011 |
ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression B Rafn, CF Nielsen, SH Andersen, P Szyniarowski, E Corcelle-Termeau, ... Molecular cell 45 (6), 764-776, 2012 | 132 | 2012 |
Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion M Björkman, P Östling, V Härmä, J Virtanen, JP Mpindi, J Rantala, T Mirtti, ... Oncogene 31 (29), 3444-3456, 2012 | 130 | 2012 |
The eNanoMapper database for nanomaterial safety information N Jeliazkova, C Chomenidis, P Doganis, B Fadeel, R Grafström, B Hardy, ... Beilstein journal of nanotechnology 6 (1), 1609-1634, 2015 | 112 | 2015 |
NanoSolveIT Project: Driving nanoinformatics research to develop innovative and integrated tools for in silico nanosafety assessment A Afantitis, G Melagraki, P Isigonis, A Tsoumanis, DD Varsou, ... Computational and Structural Biotechnology Journal 18, 583-602, 2020 | 101 | 2020 |
A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury P Kohonen, JA Parkkinen, EL Willighagen, R Ceder, K Wennerberg, ... Nature communications 8 (1), 15932, 2017 | 99 | 2017 |
High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer P Vainio, JP Mpindi, P Kohonen, V Fey, T Mirtti, KA Alanen, M Perälä, ... PloS one 7 (6), e39801, 2012 | 95 | 2012 |
Towards FAIR nanosafety data N Jeliazkova, MD Apostolova, C Andreoli, F Barone, A Barrick, ... Nature Nanotechnology 16 (6), 644-654, 2021 | 91 | 2021 |
Next-generation sequencing reveals low-dose effects of cationic dendrimers in primary human bronchial epithelial cells N Feliu, P Kohonen, J Ji, Y Zhang, HL Karlsson, L Palmberg, A Nystrom, ... ACS nano 9 (1), 146-163, 2015 | 91 | 2015 |
Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact SK Leivonen, A Rokka, P Östling, P Kohonen, GL Corthals, O Kallioniemi, ... Molecular & Cellular Proteomics 10 (7), 2011 | 89 | 2011 |
CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation P Puustinen, A Rytter, M Mortensen, P Kohonen, JM Moreira, M Jäättelä Journal of Cell Biology 204 (5), 713-727, 2014 | 85 | 2014 |
Systematic identification of microRNAs that impact on proliferation of prostate cancer cells and display changed expression in tumor tissue A Aakula, P Kohonen, SK Leivonen, R Mäkelä, P Hintsanen, JP Mpindi, ... European urology 69 (6), 1120-1128, 2016 | 77 | 2016 |