| Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction. LJ Zhao, CZ Giam Proceedings of the National Academy of Sciences 89 (15), 7070-7074, 1992 | 402 | 1992 |
| Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in … LJ Zhao, CZ Giam Proceedings of the National Academy of Sciences 88 (24), 11445-11449, 1991 | 233 | 1991 |
| An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300 R Harrod, Y Tang, C Nicot, HS Lu, A Vassilev, Y Nakatani, CZ Giam Molecular and Cellular Biology, 1998 | 222 | 1998 |
| Human T-cell lymphotropic/leukemia virus type 1 Tax abrogates p53-induced cell cycle arrest and apoptosis through its CREB/ATF functional domain JC Mulloy, T Kislyakova, A Cereseto, L Casareto, A LoMonico, J Fullen, ... Journal of virology 72 (11), 8852-8860, 1998 | 208 | 1998 |
| Life, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformation KT Jeang, C Giam, F Majone, M Aboud Journal of Biological Chemistry 279 (31), 31991-31994, 2004 | 204 | 2004 |
| Distinct regions in human T-cell lymphotropic virus type I tax mediate interactions with activator protein CREB and basal transcription factors N Adya, CZ Giam Journal of Virology 69 (3), 1834-1841, 1995 | 157 | 1995 |
| HTLV-I tax gene product activates transcription via pre-existing cellular factors and cAMP responsive element CZ Giam, YL Xu Journal of Biological Chemistry 264 (26), 15236-15241, 1989 | 155 | 1989 |
| HTLV-1 infection and adult T-cell leukemia/lymphoma—a tale of two proteins: tax and HBZ CZ Giam, OJ Semmes Viruses 8 (6), 161, 2016 | 154 | 2016 |
| p300 and p300/cAMP-responsive element-binding protein associated factor interact with human T-cell lymphotropic virus type-1 Tax in a multi-histone acetyltransferase/activator … R Harrod, YL Kuo, Y Tang, Y Yao, A Vassilev, Y Nakatani, CZ Giam Journal of Biological Chemistry 275 (16), 11852-11857, 2000 | 151 | 2000 |
| Expansion of CREB's DNA recognition specificity by Tax results from interaction with Ala-Ala-Arg at positions 282-284 near the conserved DNA-binding domain of CREB. N Adya, LJ Zhao, W Huang, I Boros, CZ Giam Proceedings of the National Academy of Sciences 91 (12), 5642-5646, 1994 | 150 | 1994 |
| NF-κB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ H Zhi, L Yang, YL Kuo, YK Ho, HM Shih, CZ Giam PLoS pathogens 7 (4), e1002025, 2011 | 148 | 2011 |
| HTLV-I Tax directly binds the Cdc20-associated anaphase-promoting complex and activates it ahead of schedule B Liu, S Hong, Z Tang, H Yu, CZ Giam Proceedings of the National Academy of Sciences 102 (1), 63-68, 2005 | 147 | 2005 |
| Mycobacterium tuberculosis and its purified protein derivative activate expression of the human immunodeficiency virus MM Lederman, DL Georges, DJ Kusner, P Mudido, CZ Giam, Z Toossi JAIDS Journal of Acquired Immune Deficiency Syndromes 7 (7), 727-733, 1994 | 145 | 1994 |
| In vitro selection of DNA elements highly responsive to the human T-cell lymphotropic virus type I transcriptional activator, Tax S Paca-Uccaralertkun, LJ Zhao, N Adya, JV Cross, BR Cullen, IM Boros, ... Molecular and Cellular Biology 14 (1), 456-462, 1994 | 137 | 1994 |
| A human suppressor of c-Jun N-terminal kinase 1 activation by tumor necrosis factor α DY Jin, H Teramoto, CZ Giam, RF Chun, JS Gutkind, KT Jeang Journal of Biological Chemistry 272 (41), 25816-25823, 1997 | 134 | 1997 |
| Human T-lymphotropic virus type I tax activates I-κB kinase by inhibiting I-κB kinase-associated serine/threonine protein phosphatase 2A DX Fu, YL Kuo, BY Liu, KT Jeang, CZ Giam Journal of Biological Chemistry 278 (3), 1487-1493, 2003 | 133 | 2003 |
| Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat F Tie, N Adya, WC Greene, CZ Giam Journal of virology 70 (12), 8368-8374, 1996 | 132 | 1996 |
| Activation of the anaphase promoting complex by HTLV‐1 tax leads to senescence YL Kuo, CZ Giam The EMBO journal 25 (8), 1741-1752, 2006 | 119 | 2006 |
| HTLV-1 Tax and adult T-cell leukemia CZ Giam, KT Jeang Front Biosci 12 (1), 1496-507, 2007 | 113 | 2007 |
| Human T-cell leukemia virus type I oncoprotein Tax represses Smad-dependent transforming growth factor β signaling through interaction with CREB-binding protein/p300 N Mori, M Morishita, T Tsukazaki, CZ Giam, A Kumatori, Y Tanaka, ... Blood, The Journal of the American Society of Hematology 97 (7), 2137-2144, 2001 | 110 | 2001 |
