Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells ST Rashid, S Corbineau, N Hannan, SJ Marciniak, E Miranda, ... The Journal of clinical investigation 120 (9), 3127-3136, 2010 | 728 | 2010 |
Extracellular vesicles: novel mediators of cell communication in metabolic disease I Huang-Doran, CY Zhang, A Vidal-Puig Trends in Endocrinology & Metabolism 28 (1), 3-18, 2017 | 352 | 2017 |
Lipodystrophy: metabolic insights from a rare disorder. I Huang-Doran, A Sleigh, JJ Rochford, S O'Rahilly, DB Savage The Journal of endocrinology 207 (3), 245-255, 2010 | 251 | 2010 |
The 148M allele of the PNPLA3 gene is associated with indices of liver damage early in life S Romeo, F Sentinelli, VM Cambuli, M Incani, T Congiu, V Matta, S Pilia, ... Journal of hepatology 53 (2), 335-338, 2010 | 172 | 2010 |
Unravelling the pathogenesis of fatty liver disease: patatin-like phospholipase domain-containing 3 protein S Romeo, I Huang-Doran, MG Baroni, A Kotronen Current opinion in lipidology 21 (3), 247-252, 2010 | 98 | 2010 |
Genetic defects in human pericentrin are associated with severe insulin resistance and diabetes I Huang-Doran, LS Bicknell, FM Finucane, N Rocha, KM Porter, YCL Tung, ... Diabetes 60 (3), 925-935, 2011 | 72 | 2011 |
Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations I Huang-Doran, P Tomlinson, F Payne, A Gast, A Sleigh, W Bottomley, ... JCI insight 1 (17), 2016 | 58 | 2016 |
The metabolic syndrome-associated small G protein ARL15 plays a role in adipocyte differentiation and adiponectin secretion N Rocha, F Payne, I Huang-Doran, A Sleigh, K Fawcett, C Adams, ... Scientific reports 7 (1), 17593, 2017 | 34 | 2017 |
Knockdown of the Alström syndrome-associated gene Alms1 in 3T3-L1 preadipocytes impairs adipogenesis but has no effect on cell-autonomous insulin action I Huang-Doran, RK Semple International journal of obesity 34 (10), 1554-1558, 2010 | 31 | 2010 |
Adiponectin and leptin in human severe insulin resistance–Diagnostic utility and biological insights MP Groeneveld, I Huang-Doran, RK Semple Biochimie 94 (10), 2172-2179, 2012 | 30 | 2012 |
Ovarian hyperandrogenism and response to gonadotropin-releasing hormone analogues in primary severe insulin resistance I Huang-Doran, AB Kinzer, M Jimenez-Linan, K Thackray, J Harris, ... The Journal of Clinical Endocrinology & Metabolism 106 (8), 2367-2383, 2021 | 29 | 2021 |
Genetic rodent models of obesity-associated ovarian dysfunction and subfertility: insights into polycystic ovary syndrome I Huang-Doran, S Franks Frontiers in endocrinology 7, 53, 2016 | 27 | 2016 |
Leptin-mediated changes in the human metabolome K Lawler, I Huang-Doran, T Sonoyama, TH Collet, JM Keogh, E Henning, ... The Journal of Clinical Endocrinology & Metabolism 105 (8), 2541-2552, 2020 | 26 | 2020 |
Truncation of POC1A associated with short stature and extreme insulin resistance JH Chen, M Segni, F Payne, I Huang-Doran, A Sleigh, C Adams, ... Journal of molecular endocrinology 55 (2), 147, 2015 | 24 | 2015 |
Membranous glomerulonephritis with crescents A Nikolopoulou, I Huang-Doran, SP McAdoo, ME Griffith, HT Cook, ... Kidney International Reports 4 (11), 1577-1584, 2019 | 22 | 2019 |
Truncation of Pik3r1 causes severe insulin resistance uncoupled from obesity and dyslipidaemia by increased energy expenditure A Kwok, I Zvetkova, S Virtue, I Luijten, I Huang-Doran, P Tomlinson, ... Molecular Metabolism 40, 101020, 2020 | 18 | 2020 |
Non-alcoholic fatty liver disease is characterised by a reduced polyunsaturated fatty acid transport via free fatty acids and high-density lipoproteins (HDL) G Mocciaro, M Allison, B Jenkins, V Azzu, I Huang-Doran, ... Molecular Metabolism 73, 101728, 2023 | 16 | 2023 |
Glucagonoma-associated dilated cardiomyopathy refractory to somatostatin analogue therapy M Barabas, I Huang-Doran, D Pitfield, H Philips, M Goonewardene, ... Endocrinology, diabetes & metabolism case reports 2019 (1), 2019 | 10 | 2019 |
Congenital syndromes of severe insulin resistance. I Huang-Doran, DB Savage Pediatric endocrinology reviews: PER 8 (3), 190-199, 2011 | 8 | 2011 |
Understanding the genetic complexity of puberty timing across the allele frequency spectrum KA Kentistou, LR Kaisinger, S Stankovic, M Vaudel, E Mendes de Oliveira, ... Nature genetics, 1-15, 2024 | 5 | 2024 |