The impact of lipophilicity on environmental processes, drug delivery and bioavailability of food components T Chmiel, A Mieszkowska, D Kempińska-Kupczyk, A Kot-Wasik, ... Microchemical Journal 146, 393-406, 2019 | 111 | 2019 |
The role of glucuronidation in drug resistance Z Mazerska, A Mróz, M Pawłowska, E Augustin Pharmacology & therapeutics 159, 35-55, 2016 | 96 | 2016 |
State of the art and prospects of methods for determination of lipophilicity of chemical compounds D Kempińska, T Chmiel, A Kot-Wasik, A Mroz, Z Mazerska, J Namieśnik TrAC Trends in Analytical Chemistry 113, 54-73, 2019 | 50 | 2019 |
Progress in targeting tumor cells by using drug-magnetic nanoparticles conjugate AM Nowicka, A Kowalczyk, A Jarzebinska, M Donten, P Krysinski, ... Biomacromolecules 14 (3), 828-833, 2013 | 45 | 2013 |
Electroanalytical and spectroscopic procedures for examination of interactions between double stranded DNA and intercalating drugs AM Nowicka, E Zabost, M Donten, Z Mazerska, Z Stojek Analytical and bioanalytical chemistry 389, 1931-1940, 2007 | 45 | 2007 |
Molecular mechanism of the enzymatic oxidation investigated for imidazoacridinone antitumor drug, C-1311 Z Mazerska, P Sowiński, J Konopa Biochemical pharmacology 66 (9), 1727-1736, 2003 | 45 | 2003 |
Improved cytotoxicity and preserved level of cell death induced in colon cancer cells by doxorubicin after its conjugation with iron-oxide magnetic nanoparticles E Augustin, B Czubek, AM Nowicka, A Kowalczyk, Z Stojek, Z Mazerska Toxicology in Vitro 33, 45-53, 2016 | 44 | 2016 |
Products of metabolic activation of the antitumor drug ledakrin (nitracrine) in vitro K Gorlewska, Z Mazerska, P Sowiński, J Konopa Chemical Research in Toxicology 14 (1), 1-10, 2001 | 42 | 2001 |
Enzymatic activation of a new antitumour drug, 5-diethylaminoethylamino-8-hydroxyimidazoacridinone, C-1311, observed after its intercalation into DNA Z Mazerska, J Dziegielewski, J Konopa Biochemical pharmacology 61 (6), 685-694, 2001 | 40 | 2001 |
Metabolic transformation of antitumor acridinone C-1305 but not C-1311 via selective cellular expression of UGT1A10 increases cytotoxic response: implications for clinical use M Pawlowska, R Chu, B Fedejko-Kap, E Augustin, Z Mazerska, ... Drug Metabolism and Disposition 41 (2), 414-421, 2013 | 39 | 2013 |
New unsymmetrical bisacridine derivatives noncovalently attached to quaternary quantum dots improve cancer therapy by enhancing cytotoxicity toward cancer cells and protecting … J Pilch, E Matysiak-Brynda, A Kowalczyk, P Bujak, Z Mazerska, ... ACS applied materials & interfaces 12 (15), 17276-17289, 2020 | 34 | 2020 |
Relationship between volatile organohalogen compounds in drinking water and human urine in Poland Ż Polkowska, K Kozłowska, Z Mazerska, T Górecki, J Namieśnik Chemosphere 53 (8), 899-909, 2003 | 28 | 2003 |
Role of human UDP-glucuronosyltransferases in the biotransformation of the triazoloacridinone and imidazoacridinone antitumor agents C-1305 and C-1311: highly selective … B Fedejko-Kap, SM Bratton, M Finel, A Radominska-Pandya, Z Mazerska Drug Metabolism and Disposition 40 (9), 1736-1743, 2012 | 27 | 2012 |
The imidazoacridinone antitumor drug, C-1311, is metabolized by flavin monooxygenases but not by cytochrome P450s A Potega, E Dabrowska, M Niemira, A Kot-Wasik, S Ronseaux, ... Drug metabolism and disposition 39 (8), 1423-1432, 2011 | 26 | 2011 |
Revision of biological methods for determination of EDC presence and their endocrine potential B Kudłak, N Szczepańska, K Owczarek, Z Mazerska, J Namieśnik Critical Reviews in Analytical Chemistry 45 (3), 191-200, 2015 | 25 | 2015 |
Metabolic transformations of antitumor imidazoacridinone, C-1311, with microsomal fractions of rat and human liver A Wiśniewska, A Chrapkowska, A Kot-Wasik, J Konopa, Z Mazerska Acta Biochimica Polonica 54, 831-838, 2007 | 25 | 2007 |
Design, synthesis and high antitumor potential of new unsymmetrical bisacridine derivatives towards human solid tumors, specifically pancreatic cancers and their unique ability … E Paluszkiewicz, B Horowska, B Borowa-Mazgaj, G Peszyńska-Sularz, ... European Journal of Medicinal Chemistry 204, 112599, 2020 | 24 | 2020 |
Binary mixtures of selected bisphenols in the environment: their toxicity in relationship to individual constituents K Owczarek, B Kudłak, V Simeonov, Z Mazerska, J Namieśnik Molecules 23 (12), 3226, 2018 | 24 | 2018 |
Pregnane X receptor dependent up-regulation of CYP2C9 and CYP3A4 in tumor cells by antitumor acridine agents, C-1748 and C-1305, selectively diminished under hypoxia M Niemira, J Dastych, Z Mazerska Biochemical Pharmacology 86 (2), 231-241, 2013 | 24 | 2013 |
Flavin monooxygenases, FMO1 and FMO3, not cytochrome P450 isoenzymes, contribute to metabolism of anti-tumour triazoloacridinone, C-1305, in liver microsomes and HepG2 cells B Fedejko-Kap, M Niemira, A Radominska-Pandya, Z Mazerska Xenobiotica 41 (12), 1044-1055, 2011 | 23 | 2011 |