| Carboxylesterase 2 and intestine transporters contribute to the low bioavailability of allisartan, a prodrug of Exp3174 for hypertension treatment in humans X Li, J Sun, Z Guo, D Zhong, X Chen Drug Metabolism and Disposition 47 (8), 843-853, 2019 | 13 | 2019 |
| Pharmacodynamic and pharmacokinetic effects of S086, a novel angiotensin receptor neprilysin inhibitor J Sun, W Xu, H Hua, Y Xiao, X Chen, Z Gao, S Li, X Jing, F Du, G Sun Biomedicine & Pharmacotherapy 129, 110410, 2020 | 8 | 2020 |
| A randomized, double-blind, placebo-controlled, single, and multiple dose-escalation Phase I clinical trial to investigate the safety, pharmacokinetic, and pharmacodynamic … Y Hu, H Zhang, X Li, J Mai, L Yang, J Yan, Y Li, J Sun, W Xu, S He, J Li, ... Expert Opinion on Investigational Drugs 31 (9), 977-985, 2022 | 4 | 2022 |
| Pharmacokinetics and safety of a single dose and multiple doses of allisartan isoproxil, an angiotensin ii receptor blocker, in healthy Chinese people W Yi, P Yan, S Lin, R Hao, Y Wang, J Yu, L Fang, J Zhu, D Zhao, S Tong, ... Clinical Pharmacology in Drug Development 11 (1), 43-50, 2022 | 4 | 2022 |
| Protective effect of novel angiotensin receptor neprilysin inhibitor S086 on target organ injury in spontaneously hypertensive rats Y Xiao, ZY Zhou, JC Sun, W Xing, J Yan, WJ Xu, YS Lu, T Liu, Y Jin Biomedicine & Pharmacotherapy 170, 115968, 2024 | 2 | 2024 |
| Allisartan Isoproxil Promotes Uric Acid Excretion by Interacting with Intestinal Urate Transporters in Hyperuricemic Zebrafish (Danio rerio) Y Xiao, Z Miao, J Sun, W Xing, Y Wei, J Bai, H Ye, Y Si, L Cai Bulletin of Experimental Biology and Medicine 175 (5), 638-643, 2023 | 2 | 2023 |
| EFFICACY AND SAFETY OF SACUBITRIL/ALLISARTAN FOR THE TREATMENT OF PRIMARY HYPERTENSION: A PHASE 3 RANDOMIZED, DOUBLE-BLIND STUDY W Zhang, J Zhang, J Yan, Q Ge, X Lu, S Chen, W Xu, J Sun, J Li, Z Liu, ... Journal of Hypertension 42 (Suppl 1), e45, 2024 | | 2024 |
| Anti-hypertensive effect of a novel angiotensin II receptor neprilysin inhibitor (ARNi)-S086 in DSS rat model J Sun, Y Xiao, W Xu, W Xing, F Du, M Tian, D Xu, Y Ren, X Fang Frontiers in Cardiovascular Medicine 11, 1348897, 2024 | | 2024 |
| Pharmacokinetics and Drug–Drug Interaction of Allisartan Isoproxil and Indapamide Sustained‐Release Formulation W Yi, S Lin, R Hao, Y Shao, Y Wang, J Yu, L Fang, J Zhu, A Wang, Y Wu, ... Clinical Pharmacology in Drug Development 12 (11), 1051-1059, 2023 | | 2023 |
