DNA deamination mediates innate immunity to retroviral infection RS Harris, KN Bishop, AM Sheehy, HM Craig, SK Petersen-Mahrt, IN Watt, ... Cell 113 (6), 803-809, 2003 | 1732 | 2003 |
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification SK Petersen-Mahrt, RS Harris, MS Neuberger Nature 418 (6893), 99-104, 2002 | 1098 | 2002 |
APOBEC3B is an enzymatic source of mutation in breast cancer MB Burns, L Lackey, MA Carpenter, A Rathore, AM Land, B Leonard, ... Nature 494 (7437), 366-370, 2013 | 888 | 2013 |
Retroviral restriction by APOBEC proteins RS Harris, MT Liddament Nature Reviews Immunology 4 (11), 868-877, 2004 | 852 | 2004 |
Evidence for APOBEC3B mutagenesis in multiple human cancers MB Burns, NA Temiz, RS Harris Nature genetics 45 (9), 977-983, 2013 | 801 | 2013 |
RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators RS Harris, SK Petersen-Mahrt, MS Neuberger Molecular cell 10 (5), 1247-1253, 2002 | 738 | 2002 |
The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G SG Conticello, RS Harris, MS Neuberger Current Biology 13 (22), 2009-2013, 2003 | 613 | 2003 |
APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo MT Liddament, WL Brown, AJ Schumacher, RS Harris Current Biology 14 (15), 1385-1391, 2004 | 551 | 2004 |
APOBECs and virus restriction RS Harris, JP Dudley Virology 479, 131-145, 2015 | 530 | 2015 |
APOBEC enzymes: mutagenic fuel for cancer evolution and heterogeneity C Swanton, N McGranahan, GJ Starrett, RS Harris Cancer discovery 5 (7), 704-712, 2015 | 480 | 2015 |
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection S Jäger, DY Kim, JF Hultquist, K Shindo, RS LaRue, E Kwon, M Li, ... Nature 481 (7381), 371-375, 2012 | 420 | 2012 |
Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction EW Refsland, MD Stenglein, K Shindo, JS Albin, WL Brown, RS Harris Nucleic acids research 38 (13), 4274-4284, 2010 | 406 | 2010 |
Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1 JF Hultquist, JA Lengyel, EW Refsland, RS LaRue, L Lackey, WL Brown, ... Journal of virology 85 (21), 11220-11234, 2011 | 403 | 2011 |
Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo RCL Beale, SK Petersen-Mahrt, IN Watt, RS Harris, C Rada, ... Journal of molecular biology 337 (3), 585-596, 2004 | 396 | 2004 |
APOBEC3 proteins mediate the clearance of foreign DNA from human cells MD Stenglein, MB Burns, M Li, J Lengyel, RS Harris Nature structural & molecular biology 17 (2), 222-229, 2010 | 389 | 2010 |
The restriction factors of human immunodeficiency virus RS Harris, JF Hultquist, DT Evans Journal of Biological Chemistry 287 (49), 40875-40883, 2012 | 348 | 2012 |
The SOS response regulates adaptive mutation GJ McKenzie, RS Harris, PL Lee, SM Rosenberg Proceedings of the National Academy of Sciences 97 (12), 6646-6651, 2000 | 340 | 2000 |
Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration JL Mbisa, R Barr, JA Thomas, N Vandegraaff, IJ Dorweiler, ... Journal of virology 81 (13), 7099-7110, 2007 | 339 | 2007 |
APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism MD Stenglein, RS Harris Journal of Biological Chemistry 281 (25), 16837-16841, 2006 | 337 | 2006 |
Recombination in adaptive mutation RS Harris, S Longerich, SM Rosenberg Science 264 (5156), 258-260, 1994 | 308 | 1994 |