Leptin modulates the intrinsic excitability of AgRP/NPY neurons in the arcuate nucleus of the hypothalamus SB Baver, K Hope, S Guyot, C Bjørbaek, C Kaczorowski, KMS O'Connell Journal of Neuroscience 34 (16), 5486-5496, 2014 | 214 | 2014 |
TRPC3 channels critically regulate hippocampal excitability and contextual fear memory SM Neuner, LA Wilmott, KA Hope, B Hoffmann, JA Chong, J Abramowitz, ... Behavioural brain research 281, 69-77, 2015 | 69 | 2015 |
Assessment of the Tumorigenic Potential of Spontaneously Immortalized and hTERT-Immortalized Cultured Dental Pulp Stem Cells R Wilson, N Urraca, C Skobowiat, KA Hope, L Miravalle, R Chamberlin, ... Stem cells translational medicine 4 (8), 905-912, 2015 | 45 | 2015 |
A recurrent de novo missense mutation in UBTF causes developmental neuroregression C Toro, RT Hori, MCV Malicdan, CJ Tifft, A Goldstein, WA Gahl, ... Human Molecular Genetics 27 (4), 691-705, 2018 | 40 | 2018 |
A Drosophila screen identifies NKCC1 as a modifier of NGLY1 deficiency DM Talsness, KG Owings, E Coelho, G Mercenne, JM Pleinis, R Partha, ... elife 9, e57831, 2020 | 39 | 2020 |
Glial overexpression of Dube3a causes seizures and synaptic impairments in Drosophila concomitant with down regulation of the Na+/K+ pump ATPα KA Hope, MS LeDoux, LT Reiter Neurobiology of disease 108, 238-248, 2017 | 30 | 2017 |
Significant transcriptional changes in 15q duplication but not Angelman syndrome deletion stem cell-derived neurons N Urraca, K Hope, AK Victor, TG Belgard, R Memon, S Goorha, C Valdez, ... Molecular autism 9, 1-16, 2018 | 26 | 2018 |
The Drosophila Gene Sulfateless Modulates Autism-Like Behaviors KA Hope, D Flatten, P Cavitch, B May, JS Sutcliffe, J O’Donnell, LT Reiter Frontiers in Genetics 10, 574, 2019 | 16 | 2019 |
An in vivo drug repurposing screen and transcriptional analyses reveals the serotonin pathway and GSK3 as major therapeutic targets for NGLY1 deficiency KA Hope, AR Berman, RT Peterson, CY Chow PLoS Genetics 18 (6), e1010228, 2022 | 13 | 2022 |
Cell-type-specific changes in intrinsic excitability in the subiculum following learning and exposure to novel environmental contexts AR Dunn, SM Neuner, S Ding, KA Hope, KMS O’Connell, ... Eneuro 5 (6), 2018 | 13 | 2018 |
An unbiased drug screen for seizure suppressors in duplication 15q syndrome reveals 5-HT1A and dopamine pathway activation as potential therapies B Roy, J Han, KA Hope, TL Peters, G Palmer, LT Reiter Biological psychiatry 88 (9), 698-709, 2020 | 10 | 2020 |
The Drosophila melanogaster homolog of UBE3A is not imprinted in neurons KA Hope, MS LeDoux, LT Reiter Epigenetics 11 (9), 637-642, 2016 | 8 | 2016 |
Parental and larval exposure to nicotine modulate spontaneous activity as well as cholinergic and GABA receptor expression in adult C. elegans JK Rose, MK Miller, SA Crane, KA Hope, PG Pittman Neurotoxicology and teratology 39, 122-127, 2013 | 7 | 2013 |
Cell-Type-Specific Changes in Intrinsic Excitability in the Subiculum following Learning and Exposure to Novel Environmental Contexts. eNeuro 2018; 5 AR Dunn, SM Neuner, S Ding, KA Hope, KMS O’Connell, ... | 5 | |
Transcriptomic and proteomic profiling of glial versus neuronal Dube3a overexpression reveals common molecular changes in gliopathic epilepsies KA Hope, D Johnson, PW Miller, D Lopez-Ferrer, D Kakhniashvili, ... Neurobiology of disease 141, 104879, 2020 | 4 | 2020 |
A genome-wide enhancer/suppressor screen for Dube3a interacting genes in Drosophila melanogaster KA Hope, A McGinn, LT Reiter Scientific Reports 9 (1), 2382, 2019 | 1 | 2019 |
Understanding human genetic disease with the fly KA Hope, LT Reiter Cellular and Animal Models in Human Genomics Research, 69-87, 2019 | 1 | 2019 |
Investigation of Cell-Type-Specific Effects and Synergistic Interactions Between Genes in Duplication 15q Syndrome KA Hope The University of Tennessee Health Science Center, 2019 | | 2019 |
Glial overexpression of the E3 ubiquitin ligase Dube3a alters Na+/K+ homeostasis and results in seizure susceptibility in a Drosophila model of Duplication 15q syndrome K Hope, D Johnson, D Kakhniashvili, L Reiter GLIA 65, E257-E258, 2017 | | 2017 |