| Single-cell transcriptomic analyses define distinct peripheral B cell subsets and discrete development pathways A Stewart, JCF Ng, G Wallis, V Tsioligka, F Fraternali, DK Dunn-Walters Frontiers in immunology 12, 602539, 2021 | 116 | 2021 |
| Tumor-infiltrating B lymphocyte profiling identifies IgG-biased, clonally expanded prognostic phenotypes in triple-negative breast cancer RJ Harris, A Cheung, JCF Ng, R Laddach, AM Chenoweth, S Crescioli, ... Cancer research 81 (16), 4290-4304, 2021 | 64 | 2021 |
| Pan-cancer transcriptomic analysis dissects immune and proliferative functions of APOBEC3 cytidine deaminases JCF Ng, J Quist, A Grigoriadis, MH Malim, F Fraternali Nucleic acids research 47 (3), 1178-1194, 2019 | 49 | 2019 |
| Mining the PDB for tractable cases where X-ray crystallography combined with fragment screens can Be used to systematically design protein–protein inhibitors: two test cases … C Nichols, J Ng, A Keshu, G Kelly, MR Conte, MS Marber, F Fraternali, ... Journal of Medicinal Chemistry 63 (14), 7559-7568, 2020 | 40 | 2020 |
| Genetic variants and protein–protein interactions: a multidimensional network-centric view A Laddach, JCF Ng, SS Chung, F Fraternali Current opinion in structural biology 50, 82-90, 2018 | 27 | 2018 |
| Pathogenic missense protein variants affect different functional pathways and proteomic features than healthy population variants A Laddach, JCF Ng, F Fraternali PLoS Biology 19 (4), e3001207, 2021 | 20 | 2021 |
| Gas abatement apparatus A Khan, Q Liang, S Malik, S Nemani, R Smati, J Ng, J O'hehir US Patent 10,675,581, 2020 | 17 | 2020 |
| Personal utility is inherent to direct-to-consumer genomic testing MWH Chung, JCF Ng Journal of medical ethics 42 (10), 649-652, 2016 | 17 | 2016 |
| B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma S Crescioli, I Correa, J Ng, ZN Willsmore, R Laddach, A Chenoweth, ... Nature communications 14 (1), 3378, 2023 | 13 | 2023 |
| Pandemic, epidemic, endemic: B cell repertoire analysis reveals unique anti-viral responses to SARS-Cov-2, Ebola and respiratory syncytial virus A Stewart, E Sinclair, JCF Ng, JS O’Hare, A Page, I Serangeli, ... Frontiers in Immunology 13, 807104, 2022 | 12 | 2022 |
| sciCSR infers B cell state transition and predicts class-switch recombination dynamics using single-cell transcriptomic data JCF Ng, G Montamat Garcia, AT Stewart, P Blair, C Mauri, ... Nature Methods 21 (5), 823-834, 2024 | 11 | 2024 |
| Autosomal recessive hypotrichosis with loose anagen hairs associated with TKFC mutations A Onoufriadis, A Cabezas, JCF Ng, J Canales, MJ Costas, JM Ribeiro, ... British Journal of Dermatology 184 (5), 935-943, 2021 | 8 | 2021 |
| A new crystal form of the SARS-CoV-2 receptor binding domain: CR3022 complex—an ideal target for in-crystal fragment screening of the ACE2 binding site surface C Nichols, J Ng, A Keshu, F Fraternali, GF De Nicola Frontiers in Pharmacology 11, 615211, 2020 | 8 | 2020 |
| Modelling the assembly and flexibility of antibody structures D Guo, ML De Sciscio, JCF Ng, F Fraternali Current Opinion in Structural Biology 84, 102757, 2024 | 6 | 2024 |
| Structural dynamics of amyloid-β aggregation in Alzheimer’s disease: computational and experimental approaches CWH Cheng, MWH Chung, JCF Ng Journal of Young Investigators 31 (6), 2016 | 5 | 2016 |
| Thioredoxin is a metabolic rheostat controlling regulatory B cells HF Bradford, TCR McDonnell, A Stewart, A Skelton, J Ng, Z Baig, ... Nature Immunology 25 (5), 873-885, 2024 | 4 | 2024 |
| In Silico and In Vitro Analysis of IL36RN Alterations Reveals Critical Residues for the Function of the Interleukin-36 Receptor Complex NK Hassi, T Weston, G Rinaldi, JC Ng, A Smahi, S Twelves, ... Journal of Investigative Dermatology 143 (12), 2468-2475. e6, 2023 | 4 | 2023 |
| Understanding the structural details of APOBEC3-DNA interactions using graph-based representations JCF Ng, F Fraternali Current Research in Structural Biology 2, 130-143, 2020 | 3 | 2020 |
| Diversification of immunoglobulin genes by gene conversion in the domestic chicken (Gallus gallus domesticus) J Mallaby, W Mwangi, J Ng, A Stewart, D Dorey-Robinson, D Kipling, ... Discovery immunology 2 (1), kyad002, 2023 | 2 | 2023 |
| Chickens, more than humans, focus the diversity of their immunoglobulin genes on the complementarity-determining region but utilise amino acids, indicative of a more cross … J Mallaby, J Ng, A Stewart, E Sinclair, D Dunn-Walters, U Hershberg Frontiers in immunology 13, 837246, 2022 | 2 | 2022 |
