Regulation of cell signalling by uPAR HW Smith, CJ Marshall Nature reviews Molecular cell biology 11 (1), 23-36, 2010 | 1099 | 2010 |
Stimulation of the weak ATPase activity of human hsp90 by a client protein SH McLaughlin, HW Smith, SE Jackson Journal of molecular biology 315 (4), 787-798, 2002 | 337 | 2002 |
uPAR promotes formation of the p130Cas–Crk complex to activate Rac through DOCK180 HW Smith, P Marra, CJ Marshall The journal of cell biology 182 (4), 777-790, 2008 | 137 | 2008 |
ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer G Deblois, HW Smith, IS Tam, SP Gravel, M Caron, P Savage, DP Labbé, ... Nature communications 7 (1), 12156, 2016 | 120 | 2016 |
Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program A Hirukawa, HW Smith, D Zuo, CR Dufour, P Savage, N Bertos, ... Nature communications 9 (1), 2547, 2018 | 82 | 2018 |
LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis E Ngan, K Stoletov, HW Smith, J Common, WJ Muller, JD Lewis, ... Nature communications 8 (1), 15059, 2017 | 74 | 2017 |
Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis R Marcotte, HW Smith, V Sanguin-Gendreau, RV McDonough, WJ Muller Proceedings of the National Academy of Sciences 109 (8), 2808-2813, 2012 | 57 | 2012 |
KIBRA (WWC1) Is a metastasis suppressor gene affected by chromosome 5q loss in triple-negative breast cancer JF Knight, VYC Sung, E Kuzmin, AL Couzens, DA de Verteuil, ... Cell reports 22 (12), 3191-3205, 2018 | 52 | 2018 |
Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy A Hirukawa, S Singh, J Wang, JP Rennhack, M Swiatnicki, ... Cell reports 29 (2), 249-257. e8, 2019 | 37 | 2019 |
Inducible and coupled expression of the polyomavirus middle T antigen and Cre recombinase in transgenic mice: an in vivo model for synthetic viability in … T Rao, JJ Ranger, HW Smith, SH Lam, L Chodosh, WJ Muller Breast Cancer Research 16, 1-14, 2014 | 36 | 2014 |
An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis HW Smith, A Hirukawa, V Sanguin-Gendreau, I Nandi, CR Dufour, D Zuo, ... Nature Communications 10 (1), 2901, 2019 | 29 | 2019 |
Transgenic mouse models—A seminal breakthrough in oncogene research HW Smith, WJ Muller Cold Spring Harbor Protocols 2013 (12), pdb. top069765, 2013 | 29 | 2013 |
An ErbB2 splice variant lacking exon 16 drives lung carcinoma HW Smith, L Yang, C Ling, A Walsh, VD Martinez, J Boucher, D Zuo, ... Proceedings of the National Academy of Sciences 117 (33), 20139-20148, 2020 | 16 | 2020 |
Integration of distinct ShcA signaling complexes promotes breast tumor growth and tyrosine kinase inhibitor resistance JR Ha, R Ahn, HW Smith, V Sabourin, S Hébert, E Cepeda Cañedo, ... Molecular Cancer Research 16 (5), 894-908, 2018 | 14 | 2018 |
Coordinated activation of c-Src and FOXM1 drives tumor cell proliferation and breast cancer progression I Nandi, HW Smith, V Sanguin-Gendreau, L Ji, A Pacis, V Papavasiliou, ... The Journal of Clinical Investigation 133 (7), 2023 | 12 | 2023 |
Elevated V–ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer AH Mohammad, SH Kim, N Bertos, W El-Assaad, I Nandi, H Smith, J Yang, ... Molecular Cancer Research 18 (10), 1477-1490, 2020 | 12 | 2020 |
Ezh2 promotes mammary tumor initiation through epigenetic regulation of the Wnt and mTORC1 signaling pathways L Liu, B Xiao, A Hirukawa, HW Smith, D Zuo, V Sanguin-Gendreau, ... Proceedings of the National Academy of Sciences 120 (33), e2303010120, 2023 | 2 | 2023 |
ARF6 controls RHOB targeting to endosomes regulating cancer cell invasion K Zaoui, HW Smith, M Park, S Duhamel Molecular & Cellular Oncology 7 (5), 1766932, 2020 | 2 | 2020 |
Abstract B007: c-Src and PRC2 activity in ErbB2-driven mammary tumorigenesis and acquired resistance to ErbB2-targeted therapy HW Smith, A Hirukawa, V Sanguin-Gendreau, D Zuo, WJ Muller Molecular Cancer Research 11 (10_Supplement), B007-B007, 2013 | 2 | 2013 |
Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency CR Dufour, H Xia, W B’chir, MC Perry, U Kuzmanov, A Gainullina, ... Communications Biology 5 (1), 955, 2022 | 1 | 2022 |