Discovering the microbial enzymes driving drug toxicity with activity-based protein profiling PB Jariwala, SJ Pellock, D Goldfarb, EW Cloer, M Artola, JB Simpson, ... ACS chemical biology 15 (1), 217-225, 2019 | 62 | 2019 |
Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract J Zhang, ME Walker, KZ Sanidad, H Zhang, Y Liang, E Zhao, ... Nature communications 13 (1), 136, 2022 | 58 | 2022 |
Analysis of RNA–protein networks with RNP-MaP defines functional hubs on RNA CA Weidmann, AM Mustoe, PB Jariwala, JM Calabrese, KM Weeks Nature Biotechnology, 2020 | 57 | 2020 |
Identification of ellagic acid rhamnoside as a bioactive component of a complex botanical extract with anti-biofilm activity BM Fontaine, K Nelson, JT Lyles, PB Jariwala, JM García-Rodriguez, ... Frontiers in Microbiology 8, 496, 2017 | 42 | 2017 |
Quantitative investigation of irinotecan metabolism, transport, and gut microbiome activation MM Parvez, A Basit, PB Jariwala, Z Gáborik, E Kis, S Heyward, ... Drug Metabolism and Disposition 49 (8), 683-693, 2021 | 40 | 2021 |
Oxygen-Dependent Globin Coupled Sensor Signaling Modulates Motility and Virulence of the Plant Pathogen Pectobacterium carotovorum JL Burns, PB Jariwala, S Rivera, BM Fontaine, L Briggs, EE Weinert ACS chemical biology 12 (8), 2070-2077, 2017 | 18 | 2017 |
Relevance of human aldoketoreductases and microbial β-glucuronidases in testosterone disposition A Basit, JK Amory, VS Mettu, CY Li, S Heyward, PB Jariwala, MR Redinbo, ... Drug Metabolism and Disposition 51 (4), 427-435, 2023 | 5 | 2023 |
Microbial β-glucuronidases drive human periodontal disease etiology AD Lietzan, JB Simpson, WG Walton, PB Jariwala, Y Xu, MH Boynton, ... Science Advances 9 (18), eadg3390, 2023 | 4 | 2023 |
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics JB Simpson, ME Walker, JJ Sekela, SM Ivey, PB Jariwala, CM Storch, ... Cell Host & Microbe 32 (6), 925-944. e10, 2024 | 1 | 2024 |
Novel mechanisms of testosterone detoxification in UGT2B17 gene deletion carriers and androgen activation by gut microbiome A Basit, J Amory, C Li, V Mettu, S Heyward, P Jariwala, M Redinbo, ... The FASEB Journal 35, 2021 | 1 | 2021 |
Advanced piperazine-containing inhibitors target microbial β-glucuronidases linked to gut toxicity AL Graboski, JB Simpson, SJ Pellock, N Mehta, BC Creekmore, ... RSC Chemical Biology, 2024 | | 2024 |
Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract Z Jianan, Z Hongna, L Yanshan, Z Ermin, CV Katherine, Y Vladimir, ... | | 2022 |
Proteomics‐Informed Scaling of Irinotecan Metabolism, Transport, and Gut Microbial Activation Explain its Intestinal Toxicity after Intravenous Dose M Parvez, A Basit, P Jariwala, Z Gáborik, E Kis, S Heyward, M Redinbo, ... The FASEB Journal 35, 2021 | | 2021 |
Elucidating the Interactions between Gut Bacterial β-Glucuronidases and Approved Drugs PB Jariwala The University of North Carolina at Chapel Hill, 2021 | | 2021 |
Novel Host and Gut Microbial Mechanisms of Testosterone Activation and Inactivation in Genetic Variants of UGT2B17 A Basit, JK Amory, V Mettu, CY Li, PB Jariwala, MR Redinbo, B Prasad Parth B. and Redinbo, Matthew R. and Prasad, Bhagwat, Novel Host and Gut …, 0 | | |