Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor A Brunet, A Bonni, MJ Zigmond, MZ Lin, P Juo, LS Hu, MJ Anderson, ... cell 96 (6), 857-868, 1999 | 8053 | 1999 |
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions PP Roux, J Blenis Microbiology and molecular biology reviews 68 (2), 320-344, 2004 | 3241 | 2004 |
Molecular mechanisms of mTOR-mediated translational control XM Ma, J Blenis Nature reviews Molecular cell biology 10 (5), 307-318, 2009 | 3122 | 2009 |
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation MC Mendoza, EE Er, J Blenis Trends in biochemical sciences 36 (6), 320-328, 2011 | 2074 | 2011 |
Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway BD Manning, AR Tee, MN Logsdon, J Blenis, LC Cantley Molecular cell 10 (1), 151-162, 2002 | 1930 | 2002 |
Signal transduction via the MAP kinases: proceed at your own RSK. J Blenis Proceedings of the National Academy of Sciences 90 (13), 5889-5892, 1993 | 1699 | 1993 |
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression DC Fingar, J Blenis Oncogene 23 (18), 3151-3171, 2004 | 1667 | 2004 |
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb AR Tee, BD Manning, PP Roux, LC Cantley, J Blenis Current biology 13 (15), 1259-1268, 2003 | 1505 | 2003 |
mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events MK Holz, BA Ballif, SP Gygi, J Blenis Cell 123 (4), 569-580, 2005 | 1479 | 2005 |
Nuclear Localization and Regulation of erk-and rsk-Encoded Protein Kinases RH Chen, C Sarnecki, J Blenis Molecular and cellular biology 12 (3), 915-927, 1992 | 1479 | 1992 |
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases J Chung, CJ Kuo, GR Crabtree, J Blenis Cell 69 (7), 1227-1236, 1992 | 1446 | 1992 |
Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation B Cheatham, CJ Vlahos, L Cheatham, L Wang, J Blenis, CR Kahn Molecular and cellular biology, 1994 | 1409 | 1994 |
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation H Zhang, D Freitas, HS Kim, K Fabijanic, Z Li, H Chen, MT Mark, H Molina, ... Nature cell biology 20 (3), 332-343, 2018 | 1392 | 2018 |
Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E DC Fingar, S Salama, C Tsou, ED Harlow, J Blenis Genes & development 16 (12), 1472-1487, 2002 | 1384 | 2002 |
Rapamycin: one drug, many effects J Li, SG Kim, J Blenis Cell metabolism 19 (3), 373-379, 2014 | 1267 | 2014 |
Molecular interpretation of ERK signal duration by immediate early gene products LO Murphy, S Smith, RH Chen, DC Fingar, J Blenis Nature cell biology 4 (8), 556-564, 2002 | 1177 | 2002 |
mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E DC Fingar, CJ Richardson, AR Tee, L Cheatham, C Tsou, J Blenis Molecular and cellular biology, 2004 | 1131 | 2004 |
ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK KW Wood, C Sarnecki, TM Roberts, J Blenis Cell 68 (6), 1041-1050, 1992 | 1126 | 1992 |
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2 MR Sprick, MA Weigand, E Rieser, CT Rauch, P Juo, J Blenis, ... Immunity 12 (6), 599-609, 2000 | 1026 | 2000 |
Tuberous sclerosis complex-1 and-2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling AR Tee, DC Fingar, BD Manning, DJ Kwiatkowski, LC Cantley, J Blenis Proceedings of the National Academy of Sciences 99 (21), 13571-13576, 2002 | 1025 | 2002 |