Short peptides self-assemble to produce catalytic amyloids CM Rufo, YS Moroz, OV Moroz, J Stöhr, TA Smith, X Hu, WF DeGrado, ... Nature chemistry 6 (4), 303-309, 2014 | 571 | 2014 |
Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions J Stöhr, JC Watts, ZL Mensinger, A Oehler, SK Grillo, SJ DeArmond, ... Proceedings of the National Academy of Sciences 109 (27), 11025-11030, 2012 | 439 | 2012 |
Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients JC Watts, C Condello, J Stöhr, A Oehler, J Lee, SJ DeArmond, L Lannfelt, ... Proceedings of the National Academy of Sciences 111 (28), 10323-10328, 2014 | 327 | 2014 |
Propagation of prions causing synucleinopathies in cultured cells AL Woerman, J Stöhr, A Aoyagi, R Rampersaud, Z Krejciova, JC Watts, ... Proceedings of the National Academy of Sciences 112 (35), E4949-E4958, 2015 | 248 | 2015 |
Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice J Stöhr, C Condello, JC Watts, L Bloch, A Oehler, M Nick, SJ DeArmond, ... Proceedings of the National Academy of Sciences 111 (28), 10329-10334, 2014 | 191 | 2014 |
Mechanisms of prion protein assembly into amyloid J Stöhr, N Weinmann, H Wille, T Kaimann, L Nagel-Steger, E Birkmann, ... Proceedings of the National Academy of Sciences 105 (7), 2409-2414, 2008 | 174 | 2008 |
Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer’s disease C Condello, T Lemmin, J Stöhr, M Nick, Y Wu, AM Maxwell, JC Watts, ... Proceedings of the National Academy of Sciences 115 (4), E782-E791, 2018 | 130 | 2018 |
Aβ and tau prion-like activities decline with longevity in the Alzheimer’s disease human brain A Aoyagi, C Condello, J Stöhr, W Yue, BM Rivera, JC Lee, AL Woerman, ... Science translational medicine 11 (490), eaat8462, 2019 | 126 | 2019 |
Zinc-binding structure of a catalytic amyloid from solid-state NMR M Lee, T Wang, OV Makhlynets, Y Wu, NF Polizzi, H Wu, PM Gosavi, ... Proceedings of the National Academy of Sciences 114 (24), 6191-6196, 2017 | 107 | 2017 |
Inhibition of cytotoxicity and amyloid fibril formation by a d-amino acid peptide that specifically binds to Alzheimer’s disease amyloid peptide K Wiesehan, J Stöhr, L Nagel-Steger, T Van Groen, D Riesner, D Willbold Protein Engineering, Design & Selection 21 (4), 241-246, 2008 | 103 | 2008 |
Structural changes of membrane-anchored native PrPC K Elfrink, J Ollesch, J Stöhr, D Willbold, D Riesner, K Gerwert Proceedings of the National Academy of Sciences 105 (31), 10815-10819, 2008 | 96 | 2008 |
Structural polymorphism of Alzheimer’s β-amyloid fibrils as controlled by an E22 switch: A solid-state NMR study MR Elkins, T Wang, M Nick, H Jo, T Lemmin, SB Prusiner, WF DeGrado, ... Journal of the American Chemical Society 138 (31), 9840-9852, 2016 | 92 | 2016 |
Assembly of natural and recombinant prion protein into fibrils KW Leffers, H Wille, J Stöhr, E Junger, SB Prusiner, D Riesner Walter de Gruyter 386 (6), 569-580, 2005 | 88 | 2005 |
Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein JC Watts, K Giles, J Stöhr, A Oehler, S Bhardwaj, SK Grillo, S Patel, ... Proceedings of the National Academy of Sciences 109 (9), 3498-3503, 2012 | 86 | 2012 |
Spontaneous generation of anchorless prions in transgenic mice J Stöhr, JC Watts, G Legname, A Oehler, A Lemus, HOB Nguyen, ... Proceedings of the National Academy of Sciences 108 (52), 21223-21228, 2011 | 82 | 2011 |
A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells J Stöhr, H Wu, M Nick, Y Wu, M Bhate, C Condello, N Johnson, J Rodgers, ... Nature chemistry 9 (9), 874-881, 2017 | 78 | 2017 |
Aβ propagation and strains: Implications for the phenotypic diversity in Alzheimer's disease C Condello, J Stöehr Neurobiology of disease 109, 191-200, 2018 | 77 | 2018 |
Protease-resistant prions selectively decrease Shadoo protein JC Watts, J Stöhr, S Bhardwaj, H Wille, A Oehler, SJ DeArmond, K Giles, ... PLoS Pathogens 7 (11), e1002382, 2011 | 48 | 2011 |
Mechanism of scrapie prion precipitation with phosphotungstate anions DJ Levine, J Stöhr, LE Falese, J Ollesch, H Wille, SB Prusiner, JR Long ACS chemical biology 10 (5), 1269-1277, 2015 | 46 | 2015 |
Prion protein—antibody complexes characterized by chromatography-coupled small-angle X-ray scattering L Carter, SJ Kim, D Schneidman-Duhovny, J Stöhr, G Poncet-Montange, ... Biophysical journal 109 (4), 793-805, 2015 | 40 | 2015 |