Sensory neurons co-opt classical immune signaling pathways to mediate chronic itch LK Oetjen, MR Mack, J Feng, TM Whelan, H Niu, CJ Guo, S Chen, ... Cell 171 (1), 217-228. e13, 2017 | 875 | 2017 |
Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus Q Liu, Z Tang, L Surdenikova, S Kim, KN Patel, A Kim, F Ru, Y Guan, ... Cell 139 (7), 1353-1365, 2009 | 826 | 2009 |
TRPA1 is required for histamine-independent, Mas-related G protein–coupled receptor–mediated itch SR Wilson, KA Gerhold, A Bifolck-Fisher, Q Liu, KN Patel, X Dong, ... Nature neuroscience 14 (5), 595-602, 2011 | 670 | 2011 |
A subpopulation of nociceptors specifically linked to itch L Han, C Ma, Q Liu, HJ Weng, Y Cui, Z Tang, Y Kim, H Nie, L Qu, KN Patel, ... Nature neuroscience 16 (2), 174-182, 2013 | 576 | 2013 |
Mechanisms of itch evoked by β-alanine Q Liu, P Sikand, C Ma, Z Tang, L Han, Z Li, S Sun, RH LaMotte, X Dong Journal of Neuroscience 32 (42), 14532-14537, 2012 | 341 | 2012 |
A novel anti-CD146 monoclonal antibody, AA98, inhibits angiogenesis and tumor growth X Yan, Y Lin, D Yang, Y Shen, M Yuan, Z Zhang, P Li, H Xia, L Li, D Luo, ... Blood 102 (1), 184-191, 2003 | 283 | 2003 |
The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia Q Liu, HJ Weng, KN Patel, Z Tang, H Bai, M Steinhoff, X Dong Science signaling 4 (181), ra45-ra45, 2011 | 258 | 2011 |
Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch Q Liu, S Vrontou, FL Rice, MJ Zylka, X Dong, DJ Anderson Nature neuroscience 10 (8), 946-948, 2007 | 248 | 2007 |
Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1 AY Kim, Z Tang, Q Liu, KN Patel, D Maag, Y Geng, X Dong Cell 133 (3), 475-485, 2008 | 227 | 2008 |
TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice T Liu, T Berta, ZZ Xu, CK Park, L Zhang, N Lü, Q Liu, Y Liu, YJ Gao, ... The Journal of clinical investigation 122 (6), 2195-2207, 2012 | 183 | 2012 |
Leaky gate model: intensity-dependent coding of pain and itch in the spinal cord S Sun, Q Xu, C Guo, Y Guan, Q Liu, X Dong Neuron 93 (4), 840-853. e5, 2017 | 169 | 2017 |
A basophil-neuronal axis promotes itch F Wang, AM Trier, F Li, S Kim, Z Chen, JN Chai, MR Mack, SA Morrison, ... Cell 184 (2), 422-440. e17, 2021 | 159 | 2021 |
Transient receptor potential vanilloid 4–expressing macrophages and keratinocytes contribute differentially to allergic and nonallergic chronic itch J Luo, J Feng, G Yu, P Yang, MR Mack, J Du, W Yu, A Qian, Y Zhang, ... Journal of Allergy and Clinical Immunology 141 (2), 608-619. e7, 2018 | 97 | 2018 |
Mas-related G-protein–coupled receptors inhibit pathological pain in mice Y Guan, Q Liu, Z Tang, SN Raja, DJ Anderson, X Dong Proceedings of the National Academy of Sciences 107 (36), 15933-15938, 2010 | 93 | 2010 |
Pirt, a TRPV1 modulator, is required for histamine-dependent and-independent itch KN Patel, Q Liu, S Meeker, BJ Undem, X Dong PloS one 6 (5), e20559, 2011 | 80 | 2011 |
TRPV1 activity and substance P release are required for corneal cold nociception F Li, W Yang, H Jiang, C Guo, AJW Huang, H Hu, Q Liu Nature communications 10 (1), 5678, 2019 | 74 | 2019 |
Facilitation of MrgprD by TRP-A1 promotes neuropathic pain C Wang, L Gu, Y Ruan, X Geng, M Xu, N Yang, L Yu, Y Jiang, C Zhu, ... The FASEB Journal 33 (1), 1360, 2019 | 70 | 2019 |
Pre-eclampsia is associated with the failure of melanoma cell adhesion molecule (MCAM/CD146) expression by intermediate trophoblast Q Liu, X Yan, Y Li, Y Zhang, X Zhao, Y Shen Laboratory investigation 84 (2), 221-228, 2004 | 69 | 2004 |
Anatomical and functional dichotomy of ocular itch and pain CC Huang, W Yang, C Guo, H Jiang, F Li, M Xiao, S Davidson, G Yu, ... Nature medicine 24 (8), 1268-1276, 2018 | 60 | 2018 |
IL-33 signaling in sensory neurons promotes dry skin itch AM Trier, MR Mack, A Fredman, M Tamari, AM Ver Heul, Y Zhao, CJ Guo, ... Journal of Allergy and Clinical Immunology 149 (4), 1473-1480. e6, 2022 | 57 | 2022 |