Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli T Wu, AC McCandlish, LS Gronenberg, SS Chng, TJ Silhavy, D Kahne Proceedings of the National Academy of Sciences 103 (31), 11754-11759, 2006 | 433 | 2006 |
Characterization of the two-protein complex in Escherichia coli responsible for lipopolysaccharide assembly at the outer membrane SS Chng, N Ruiz, G Chimalakonda, TJ Silhavy, D Kahne Proceedings of the National Academy of Sciences 107 (12), 5363-5368, 2010 | 260 | 2010 |
The complex that inserts lipopolysaccharide into the bacterial outer membrane forms a two-protein plug-and-barrel E Freinkman, SS Chng, D Kahne Proceedings of the National Academy of Sciences 108 (6), 2486-2491, 2011 | 225 | 2011 |
Development of a highly α-regioselective metal-mediated allylation reaction in aqueous media: New mechanistic proposal for the origin of α-homoallylic alcohols KT Tan, SS Chng, HS Cheng, TP Loh Journal of the American Chemical Society 125 (10), 2958-2963, 2003 | 209 | 2003 |
Proteins Required for Lipopolysaccharide Assembly in Escherichia coli Form a Transenvelope Complex SS Chng, LS Gronenberg, D Kahne Biochemistry 49 (22), 4565-4567, 2010 | 197 | 2010 |
MmpL3 is the flippase for mycolic acids in mycobacteria Z Xu, VA Meshcheryakov, G Poce, SS Chng Proceedings of the National Academy of Sciences 114 (30), 7993-7998, 2017 | 179 | 2017 |
Lipoprotein LptE is required for the assembly of LptD by the β-barrel assembly machine in the outer membrane of Escherichia coli G Chimalakonda, N Ruiz, SS Chng, RA Garner, D Kahne, TJ Silhavy Proceedings of the National Academy of Sciences 108 (6), 2492-2497, 2011 | 156 | 2011 |
Osmoporin OmpC forms a complex with MlaA to maintain outer membrane lipid asymmetry in Escherichia coli ZS Chong, WF Woo, SS Chng Molecular microbiology 98 (6), 1133-1146, 2015 | 149 | 2015 |
Nonconsecutive disulfide bond formation in an essential integral outer membrane protein N Ruiz, SS Chng, A Hiniker, D Kahne, TJ Silhavy Proceedings of the National Academy of Sciences 107 (27), 12245-12250, 2010 | 144 | 2010 |
Defining key roles for auxiliary proteins in an ABC transporter that maintains bacterial outer membrane lipid asymmetry S Thong, B Ercan, F Torta, ZY Fong, HYA Wong, MR Wenk, SS Chng Elife 5, e19042, 2016 | 128 | 2016 |
Disulfide rearrangement triggered by translocon assembly controls lipopolysaccharide export SS Chng, M Xue, RA Garner, H Kadokura, D Boyd, J Beckwith, D Kahne Science 337 (6102), 1665-1668, 2012 | 116 | 2012 |
Outer membrane lipid homeostasis via retrograde phospholipid transport in Escherichia coli R Shrivastava, XE Jiang, SS Chng Molecular microbiology 106 (3), 395-408, 2017 | 87 | 2017 |
Lewis acid-promoted intermolecular acetal-initiated cationic polyene cyclizations YJ Zhao, SS Chng, TP Loh Journal of the American Chemical Society 129 (3), 492-493, 2007 | 85 | 2007 |
Lipid trafficking across the Gram-negative cell envelope R Shrivastava, SS Chng Journal of Biological Chemistry 294 (39), 14175-14184, 2019 | 81 | 2019 |
The architecture of the OmpC–MlaA complex sheds light on the maintenance of outer membrane lipid asymmetry in Escherichia coli J Yeow, KW Tan, DA Holdbrook, ZS Chong, JK Marzinek, PJ Bond, ... Journal of Biological Chemistry 293 (29), 11325-11340, 2018 | 78 | 2018 |
MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasis GL Isom, NJ Davies, ZS Chong, JA Bryant, M Jamshad, M Sharif, ... Scientific reports 7 (1), 8608, 2017 | 66 | 2017 |
Characterization of interactions and phospholipid transfer between substrate binding proteins of the OmpC-Mla system B Ercan, WY Low, X Liu, SS Chng Biochemistry 58 (2), 114-119, 2018 | 57 | 2018 |
A piperidinol-containing molecule is active against Mycobacterium tuberculosis by inhibiting the mycolic acid flippase activity of MmpL3 C Dupont, Y Chen, Z Xu, F Roquet-Banères, M Blaise, AK Witt, F Dubar, ... Journal of Biological Chemistry 294 (46), 17512-17523, 2019 | 35 | 2019 |
Novel acetamide indirectly targets mycobacterial transporter MmpL3 by proton motive force disruption A Shetty, Z Xu, U Lakshmanan, J Hill, ML Choong, SS Chng, Y Yamada, ... Frontiers in microbiology 9, 2960, 2018 | 35 | 2018 |
Overexpression of the rhodanese PspE, a single cysteine‐containing protein, restores disulphide bond formation to an Escherichia coli strain lacking DsbA SS Chng, RJ Dutton, K Denoncin, D Vertommen, JF Collet, H Kadokura, ... Molecular microbiology 85 (5), 996-1006, 2012 | 30 | 2012 |