Elucidating the structures of amyloid oligomers with macrocyclic β-hairpin peptides: insights into Alzheimer’s disease and other amyloid diseases AG Kreutzer, JS Nowick Accounts of chemical research 51 (3), 706-718, 2018 | 107 | 2018 |
X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an Aβ17–36 β-Hairpin AG Kreutzer, IL Hamza, RK Spencer, JS Nowick Journal of the American Chemical Society 138 (13), 4634-4642, 2016 | 84 | 2016 |
Stabilization, assembly, and toxicity of trimers derived from Aβ AG Kreutzer, S Yoo, RK Spencer, JS Nowick Journal of the American Chemical Society 139 (2), 966-975, 2017 | 69 | 2017 |
A cyclic peptide inhibitor of the SARS-CoV-2 main protease AG Kreutzer, M Krumberger, EM Diessner, CMT Parrocha, MA Morris, ... European journal of medicinal chemistry 221, 113530, 2021 | 38 | 2021 |
Structure-based drug design of an inhibitor of the SARS-CoV-2 (COVID-19) main protease using free software: A tutorial for students and scientists S Zhang, M Krumberger, MA Morris, CMT Parrocha, AG Kreutzer, ... European journal of medicinal chemistry 218, 113390, 2021 | 36 | 2021 |
Repurposing triphenylmethane dyes to bind to trimers derived from Aβ PJ Salveson, S Haerianardakani, A Thuy-Boun, S Yoo, AG Kreutzer, ... Journal of the American Chemical Society 140 (37), 11745-11754, 2018 | 31 | 2018 |
X-ray Crystallographic Structure of a Compact Dodecamer from a Peptide Derived from Aβ16–36 PJ Salveson, RK Spencer, AG Kreutzer, JS Nowick Organic letters 19 (13), 3462-3465, 2017 | 31 | 2017 |
X-ray Crystallographic Structures of Oligomers of Peptides Derived from β2-Microglobulin RK Spencer, AG Kreutzer, PJ Salveson, H Li, JS Nowick Journal of the American Chemical Society 137 (19), 6304-6311, 2015 | 30 | 2015 |
Exploring amyloid oligomers with peptide model systems TD Samdin, AG Kreutzer, JS Nowick Current opinion in chemical biology 64, 106-115, 2021 | 27 | 2021 |
A Hexamer of a Peptide Derived from Aβ16–36 AG Kreutzer, RK Spencer, KJ McKnelly, S Yoo, IL Hamza, PJ Salveson, ... Biochemistry 56 (45), 6061-6071, 2017 | 27 | 2017 |
Controlling the oligomerization state of Aβ-derived peptides with light PJ Salveson, S Haerianardakani, A Thuy-Boun, AG Kreutzer, JS Nowick Journal of the American Chemical Society 140 (17), 5842-5852, 2018 | 26 | 2018 |
An efficient method for the expression and purification of Aβ (M1–42) S Yoo, S Zhang, AG Kreutzer, JS Nowick Biochemistry 57 (26), 3861-3866, 2018 | 22 | 2018 |
X-ray Crystallography Reveals Parallel and Antiparallel β-Sheet Dimers of a β-Hairpin Derived from Aβ16–36 that Assemble to Form Different Tetramers AG Kreutzer, TD Samdin, G Guaglianone, RK Spencer, JS Nowick ACS chemical neuroscience 11 (15), 2340-2347, 2020 | 20 | 2020 |
Peptidic inhibitors of insulin-degrading enzyme with potential for dermatological applications discovered via phage display CN Suire, S Nainar, M Fazio, AG Kreutzer, T Paymozd-Yazdi, CL Topper, ... PLoS One 13 (2), e0193101, 2018 | 20 | 2018 |
Effects of N-terminal residues on the assembly of constrained β-hairpin peptides derived from Aβ TD Samdin, M Wierzbicki, AG Kreutzer, WJ Howitz, M Valenzuela, A Smith, ... Journal of the American Chemical Society 142 (26), 11593-11601, 2020 | 14 | 2020 |
A tetramer derived from islet amyloid polypeptide Y Wang, AG Kreutzer, NL Truex, JS Nowick The Journal of organic chemistry 82 (15), 7905-7912, 2017 | 13 | 2017 |
Square channels formed by a peptide derived from transthyretin S Yoo, AG Kreutzer, NL Truex, JS Nowick Chemical Science 7 (12), 6946-6951, 2016 | 11 | 2016 |
Effects of Familial Alzheimer’s Disease Mutations on the Assembly of a β-Hairpin Peptide Derived from Aβ16–36 KJ McKnelly, AG Kreutzer, WJ Howitz, K Haduong, S Yoo, C Hart, ... Biochemistry 61 (6), 446-454, 2022 | 9 | 2022 |
Phenylalanine mutation to cyclohexylalanine facilitates triangular trimer formation by β-hairpins derived from Aβ S Haerianardakani, AG Kreutzer, PJ Salveson, TD Samdin, ... Journal of the American Chemical Society 142 (49), 20708-20716, 2020 | 9 | 2020 |
A disulfide-stabilized Aβ that forms dimers but does not form fibrils S Zhang, S Yoo, DT Snyder, BB Katz, A Henrickson, B Demeler, ... Biochemistry 61 (4), 252-264, 2022 | 8 | 2022 |