| Lipophilic permeability efficiency reconciles the opposing roles of lipophilicity in membrane permeability and aqueous solubility MR Naylor, AM Ly, MJ Handford, DP Ramos, CR Pye, A Furukawa, ... Journal of medicinal chemistry 61 (24), 11169-11182, 2018 | 138 | 2018 |
| Understanding and improving the membrane permeability of VH032-based PROTACs VG Klein, CE Townsend, A Testa, M Zengerle, C Maniaci, SJ Hughes, ... ACS Medicinal Chemistry Letters 11 (9), 1732-1738, 2020 | 97 | 2020 |
| Amide-to-ester substitution as a strategy for optimizing PROTAC permeability and cellular activity VG Klein, AG Bond, C Craigon, RS Lokey, A Ciulli Journal of medicinal chemistry 64 (24), 18082-18101, 2021 | 81 | 2021 |
| Drug‐Like Properties in Macrocycles above MW 1000: Backbone Rigidity versus Side‐Chain Lipophilicity A Furukawa, J Schwochert, CR Pye, D Asano, QD Edmondson, ... Angewandte Chemie International Edition 59 (48), 21571-21577, 2020 | 56 | 2020 |
| Identifying the Cellular Target of Cordyheptapeptide A and Synthetic Derivatives VG Klein, WM Bray, HY Wang, Q Edmondson, J Schwochert, S Ono, ... ACS Chemical Biology, 2021 | 6 | 2021 |
| Beyond Rule of 5 Drug Discovery: Investigating the Drug-like Properties of Cyclic Peptide V Klein | | 2020 |
| Beyond Rule of 5 Drug Discovery: Investigating the Drug-Like Properties of Cyclic Peptide Natural Products and PROTACs V Klein University of California, Santa Cruz, 2020 | | 2020 |
