Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates J Damas, GM Hughes, KC Keough, CA Painter, NS Persky, M Corbo, ... Proceedings of the National Academy of Sciences 117 (36), 22311-22322, 2020 | 642 | 2020 |
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 635 | 2020 |
Single-cell epigenomics reveals mechanisms of human cortical development RS Ziffra, CN Kim, JM Ross, A Wilfert, TN Turner, M Haeussler, ... Nature 598 (7879), 205-213, 2021 | 179 | 2021 |
Evolutionary constraint and innovation across hundreds of placental mammals MJ Christmas, IM Kaplow, DP Genereux, MX Dong, GM Hughes, X Li, ... Science 380 (6643), eabn3943, 2023 | 96 | 2023 |
Immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated inhibitory signaling is regulated by sequential phosphorylation mediated by distinct nonreceptor tyrosine kinases … BE Tourdot, MK Brenner, KC Keough, T Holyst, PJ Newman, DK Newman Biochemistry 52 (15), 2597-2608, 2013 | 57 | 2013 |
A genomic timescale for placental mammal evolution NM Foley, VC Mason, AJ Harris, KR Bredemeyer, J Damas, HA Lewin, ... Science 380 (6643), eabl8189, 2023 | 52 | 2023 |
Integrating gene annotation with orthology inference at scale BM Kirilenko, C Munegowda, E Osipova, D Jebb, V Sharma, M Blumer, ... Science 380 (6643), eabn3107, 2023 | 49 | 2023 |
Machine learning dissection of human accelerated regions in primate neurodevelopment S Whalen, F Inoue, H Ryu, T Fair, E Markenscoff-Papadimitriou, K Keough, ... Neuron 111 (6), 857-873. e8, 2023 | 45 | 2023 |
Leveraging base-pair mammalian constraint to understand genetic variation and human disease PF Sullivan, JRS Meadows, S Gazal, BDN Phan, X Li, DP Genereux, ... Science 380 (6643), eabn2937, 2023 | 44 | 2023 |
Massively parallel dissection of human accelerated regions in human and chimpanzee neural progenitors H Ryu, F Inoue, S Whalen, A Williams, M Kircher, B Martin, B Alvarado, ... BioRxiv 256313, 2018 | 41 | 2018 |
Three-dimensional genome rewiring in loci with human accelerated regions KC Keough, S Whalen, F Inoue, PF Przytycki, T Fair, C Deng, M Steyert, ... Science 380 (6643), eabm1696, 2023 | 33 | 2023 |
Insights into mammalian TE diversity through the curation of 248 genome assemblies AB Osmanski, NS Paulat, J Korstian, JR Grimshaw, M Halsey, ... Science 380 (6643), eabn1430, 2023 | 31 | 2023 |
Mammalian evolution of human cis-regulatory elements and transcription factor binding sites G Andrews, K Fan, HE Pratt, N Phalke, Zoonomia Consortium §, ... Science 380 (6643), eabn7930, 2023 | 30 | 2023 |
Relating enhancer genetic variation across mammals to complex phenotypes using machine learning IM Kaplow, AJ Lawler, DE Schäffer, C Srinivasan, HH Sestili, ME Wirthlin, ... Science 380 (6643), eabm7993, 2023 | 29 | 2023 |
The contribution of historical processes to contemporary extinction risk in placental mammals AP Wilder, MA Supple, A Subramanian, A Mudide, R Swofford, ... Science 380 (6643), eabn5856, 2023 | 28 | 2023 |
AlleleAnalyzer: a tool for personalized and allele-specific sgRNA design KC Keough, S Lyalina, MP Olvera, S Whalen, BR Conklin, KS Pollard Genome biology 20, 1-9, 2019 | 28 | 2019 |
An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype PP Shah, KC Keough, K Gjoni, GT Santini, RJ Abdill, NM Wickramasinghe, ... Genome biology 24 (1), 16, 2023 | 26 | 2023 |
The functional and evolutionary impacts of human-specific deletions in conserved elements JR Xue, A Mackay-Smith, K Mouri, MF Garcia, MX Dong, JF Akers, ... Science 380 (6643), eabn2253, 2023 | 17 | 2023 |
Reconstructing the 3D genome organization of Neanderthals reveals that chromatin folding shaped phenotypic and sequence divergence E McArthur, DC Rinker, EN Gilbertson, G Fudenberg, M Pittman, ... Biorxiv, 2022.02. 07.479462, 2022 | 17 | 2022 |
ASEPTIC MENINGITIS OUTBREAK ASSOCIATED WITH ECHOVIRUS 30 AMONG HIGH SCHOOL FOOTBALL PLAYERS LOS ANGELES COUNTY, CALIFORNIA 2014 C Croker, K Keough, MPH Van Ngo, A Marutani, R Civen Special Studies Report 5, 25, 2015 | 15 | 2015 |