Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible B Hinkes, RC Wiggins, R Gbadegesin, CN Vlangos, D Seelow, ... Nature genetics 38 (12), 1397-1405, 2006 | 677 | 2006 |
Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization R Verma, I Kovari, A Soofi, D Nihalani, K Patrie, LB Holzman The Journal of clinical investigation 116 (5), 1346-1359, 2006 | 424 | 2006 |
Nephrin localizes to the slit pore of the glomerular epithelial cell LB Holzman, PLST John, IA Kovari, R Verma, H Holthofer, ... Kidney international 56 (4), 1481-1491, 1999 | 394 | 1999 |
Fyn binds to and phosphorylates the kidney slit diaphragm component Nephrin R Verma, B Wharram, I Kovari, R Kunkel, D Nihalani, KK Wary, ... Journal of Biological Chemistry 280 (28), 2005 | 301 | 2005 |
In vivo, Pikfyve generates PI (3, 5) P2, which serves as both a signaling lipid and the major precursor for PI5P SN Zolov, D Bridges, Y Zhang, WW Lee, E Riehle, R Verma, GM Lenk, ... Proceedings of the National Academy of Sciences 109 (43), 17472-17477, 2012 | 254 | 2012 |
Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis hetero-oligomers GM Barletta, IA Kovari, RK Verma, D Kerjaschki, LB Holzman Journal of Biological Chemistry 278 (21), 19266-19271, 2003 | 253 | 2003 |
Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization P Garg, R Verma, D Nihalani, DB Johnstone, LB Holzman Molecular and cellular biology, 2007 | 190 | 2007 |
Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture P Garg, R Verma, L Cook, A Soofi, M Venkatareddy, B George, K Mizuno, ... Journal of Biological Chemistry 285 (29), 22676-22688, 2010 | 135 | 2010 |
Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease B George, R Verma, AA Soofi, P Garg, J Zhang, TJ Park, L Giardino, ... The Journal of clinical investigation 122 (2), 674-692, 2012 | 133 | 2012 |
Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1 MC Wagner, G Rhodes, E Wang, V Pruthi, E Arif, MA Saleem, SE Wean, ... Journal of Biological Chemistry 283 (51), 35579-35589, 2008 | 99 | 2008 |
Nephrin is necessary for podocyte recovery following injury in an adult mature glomerulus R Verma, M Venkatareddy, A Kalinowski, T Li, J Kukla, A Mollin, ... PLoS One 13 (6), e0198013, 2018 | 65 | 2018 |
Nephrin regulates lamellipodia formation by assembling a protein complex that includes Ship2, filamin and lamellipodin M Venkatareddy, L Cook, K Abuarquob, R Verma, P Garg PloS one 6 (12), e28710, 2011 | 61 | 2011 |
Crk1/2 and CrkL form a hetero-oligomer and functionally complement each other during podocyte morphogenesis B George, Q Fan, CP Dlugos, AA Soofi, J Zhang, R Verma, TJ Park, ... Kidney international 85 (6), 1382-1394, 2014 | 45 | 2014 |
Endoplasmic reticulum–associated degradation is required for nephrin maturation and kidney glomerular filtration function S Yoshida, X Wei, G Zhang, CL O’Connor, M Torres, Z Zhou, L Lin, ... The Journal of Clinical Investigation 131 (7), 2021 | 41 | 2021 |
Slit diaphragm junctional complex and regulation of the cytoskeleton P Garg, R Verma, LB Holzman Nephron Experimental Nephrology 106 (2), e67-e72, 2007 | 40 | 2007 |
Shp2 associates with and enhances nephrin tyrosine phosphorylation and is necessary for foot process spreading in mouse models of podocyte injury R Verma, M Venkatareddy, A Kalinowski, SR Patel, DJ Salant, P Garg Molecular and cellular biology 36 (4), 596-614, 2016 | 37 | 2016 |
Src family kinases directly regulate JIP1 module dynamics and activation D Nihalani, H Wong, R Verma, LB Holzman Molecular and cellular biology 27 (7), 2431-2441, 2007 | 35 | 2007 |
Differential effect of anti-B7-1 and anti-M150 antibodies in restricting the delivery of costimulatory signals from B cells and macrophages JN Agrewala, S Suvas, RK Verma, GC Mishra The Journal of Immunology 160 (3), 1067-1077, 1998 | 32 | 1998 |
Glomerular endothelial cells and podocytes can express CD80 in patients with minimal change disease during relapse G Cara-Fuentes, M Venkatareddy, R Verma, A Segarra, AC Cleuren, ... Pediatric Nephrology 35, 1887-1896, 2020 | 18 | 2020 |
Distinct requirements for vacuolar protein sorting 34 downstream effector phosphatidylinositol 3-phosphate 5-kinase in podocytes versus proximal tubular cells M Venkatareddy, R Verma, A Kalinowski, SR Patel, A Shisheva, P Garg Journal of the American Society of Nephrology 27 (9), 2702-2719, 2016 | 18 | 2016 |