| In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer Z Chen, E Arai, O Khan, Z Zhang, SF Ngiow, Y He, H Huang, S Manne, ... Cell 184 (5), 1262-1280. e22, 2021 | 125 | 2021 |
| Genome-wide association analyses identify new loci influencing intraocular pressure XR Gao, H Huang, DR Nannini, F Fan, H Kim Human molecular genetics 27 (12), 2205-2213, 2018 | 85 | 2018 |
| Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics JR Giles, SF Ngiow, S Manne, AE Baxter, O Khan, P Wang, R Staupe, ... Nature immunology 23 (11), 1600-1613, 2022 | 84 | 2022 |
| Genome-wide association analyses identify 139 loci associated with macular thickness in the UK Biobank cohort XR Gao, H Huang, H Kim Human molecular genetics 28 (7), 1162-1172, 2019 | 78 | 2019 |
| Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers JR Giles, S Manne, E Freilich, DA Oldridge, AE Baxter, S George, Z Chen, ... Immunity 55 (3), 557-574. e7, 2022 | 64 | 2022 |
| Polygenic risk score is associated with intraocular pressure and improves glaucoma prediction in the UK Biobank cohort XR Gao, H Huang, H Kim Translational vision science & technology 8 (2), 10-10, 2019 | 40 | 2019 |
| ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency Z Cao, KA Budinich, H Huang, D Ren, B Lu, Z Zhang, Q Chen, Y Zhou, ... Molecular cell 81 (17), 3604-3622. e10, 2021 | 39 | 2021 |
| Efficient engineering of human and mouse primary cells using peptide-assisted genome editing Z Zhang, AE Baxter, D Ren, K Qin, Z Chen, SM Collins, H Huang, ... Nature Biotechnology 42 (2), 305-315, 2024 | 23 | 2024 |
| Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure JC Beltra, MS Abdel-Hakeem, S Manne, Z Zhang, H Huang, M Kurachi, ... Immunity 56 (12), 2699-2718. e11, 2023 | 15 | 2023 |
| The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells AE Baxter, H Huang, JR Giles, Z Chen, JE Wu, S Drury, K Dalton, SL Park, ... Immunity 56 (6), 1320-1340. e10, 2023 | 15 | 2023 |
| Enhanced STAT5a activation rewires exhausted CD8 T cells during chronic stimulation to acquire a hybrid durable effector like state JC Beltra, MS Abdel-Hakeem, S Manne, Z Zhang, H Huang, M Kurachi, ... BioRxiv, 2022.10. 03.509766, 2022 | 12 | 2022 |
| In vitro modeling of CD8+ T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40 JE Wu, S Manne, SF Ngiow, AE Baxter, H Huang, E Freilich, ML Clark, ... Science Immunology 8 (86), eade3369, 2023 | 9 | 2023 |
| PleioNet: a web-based visualization tool for exploring pleiotropy across complex traits XR Gao, H Huang Bioinformatics 35 (20), 4179-4180, 2019 | 8 | 2019 |
| Longitudinal single cell transcriptional and epigenetic mapping of effector, memory, and exhausted CD8 T cells reveals shared biological circuits across distinct cell fates JR Giles, SF Ngiow, S Manne, AE Baxter, O Khan, P Wang, R Staupe, ... bioRxiv, 2022.03. 27.485974, 2022 | 6 | 2022 |
| In vivo CRISPR screening identifies Fli1 as a transcriptional safeguard that restrains effector CD8 T cell differentiation during infection and cancer Z Chen, E Arai, O Khan, Z Zhang, SF Ngiow, Y He, H Huang, S Manne, ... bioRxiv, 2020.05. 20.087379, 2020 | 4 | 2020 |
| Histone acetylation in an Alzheimer’s disease cell model promotes homeostatic amyloid-reducing pathways DC Xu, H Sas-Nowosielska, G Donahue, H Huang, N Pourshafie, ... Acta Neuropathologica Communications 12 (1), 3, 2024 | 3 | 2024 |
| TET2 controls differentiation of terminally exhausted CD8 T cells MS Jordan, S Drury, JR Giles, S Manne, H Huang, Z Chen, D Oldridge, ... The Journal of Immunology 206 (1_Supplement), 14.07-14.07, 2021 | 2 | 2021 |
| Dissection of the MEF2D-IRF8 transcriptional circuit dependency in acute myeloid leukemia BY Pingul, H Huang, Q Chen, F Alikarami, Z Zhang, J Qi, KM Bernt, ... Iscience 25 (10), 2022 | 1 | 2022 |
| 101 juvenile myositis patients characterized by myositis specific antibodies: disease activity and damage over 60 months LM Pachman, ML Curran, GA Morgan, IRA Targoff, H Huang, D Xu, ... ARTHRITIS & RHEUMATOLOGY 69, 2017 | 1 | 2017 |
| CRISPR functional genetic screening for immune enhancers of inhibitor receptors in human primary CD8 T cells P Wang, JR Giles, H Huang, J Shi, EJ Wherry Cancer Research 84 (6_Supplement), 1689-1689, 2024 | | 2024 |
