α-Synuclein locus triplication causes Parkinson's disease AB Singleton, M Farrer, J Johnson, A Singleton, S Hague, J Kachergus, ... science 302 (5646), 841-841, 2003 | 5243 | 2003 |
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD AE Renton, E Majounie, A Waite, J Simón-Sánchez, S Rollinson, ... Neuron 72 (2), 257-268, 2011 | 4766 | 2011 |
Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium IG McKeith, BF Boeve, DW Dickson, G Halliday, JP Taylor, D Weintraub, ... Neurology 89 (1), 88-100, 2017 | 3515 | 2017 |
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ... Nature genetics 41 (10), 1088-1093, 2009 | 3326 | 2009 |
TREM2 variants in Alzheimer's disease R Guerreiro, A Wojtas, J Bras, M Carrasquillo, E Rogaeva, E Majounie, ... New England Journal of Medicine 368 (2), 117-127, 2013 | 3125 | 2013 |
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease C Paisán-Ruı́z, S Jain, EW Evans, WP Gilks, J Simón, M Van Der Brug, ... Neuron 44 (4), 595-600, 2004 | 2776 | 2004 |
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ... Nature genetics 42 (2), 105-116, 2010 | 2540 | 2010 |
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk CKDGen Consortium, KidneyGen Consortium, EchoGen consortium, ... Nature 478 (7367), 103-109, 2011 | 2303 | 2011 |
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2273 | 2019 |
Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease E Sidransky, MA Nalls, JO Aasly, J Aharon-Peretz, G Annesi, ER Barbosa, ... New England Journal of Medicine 361 (17), 1651-1661, 2009 | 2264 | 2009 |
Genome-wide association study reveals genetic risk underlying Parkinson's disease J Simon-Sanchez, C Schulte, JM Bras, M Sharma, JR Gibbs, D Berg, ... Nature genetics 41 (12), 1308-1312, 2009 | 2206 | 2009 |
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ... Nature genetics 43 (5), 429-435, 2011 | 2195 | 2011 |
Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia T Walsh, JM McClellan, SE McCarthy, AM Addington, SB Pierce, ... science 320 (5875), 539-543, 2008 | 2131 | 2008 |
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease MA Nalls, N Pankratz, CM Lill, CB Do, DG Hernandez, M Saad, ... Nature genetics 46 (9), 989-993, 2014 | 2008 | 2014 |
Systematic identification of trans eQTLs as putative drivers of known disease associations HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ... Nature genetics 45 (10), 1238-1243, 2013 | 1901 | 2013 |
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies MA Nalls, C Blauwendraat, CL Vallerga, K Heilbron, S Bandres-Ciga, ... The Lancet Neurology 18 (12), 1091-1102, 2019 | 1637 | 2019 |
The Parkinson progression marker initiative (PPMI) K Marek, D Jennings, S Lasch, A Siderowf, C Tanner, T Simuni, C Coffey, ... Progress in neurobiology 95 (4), 629-635, 2011 | 1555 | 2011 |
A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci D Chang, MA Nalls, IB Hallgrímsdóttir, J Hunkapiller, M Van Der Brug, ... Nature genetics 49 (10), 1511-1516, 2017 | 1100 | 2017 |
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium The Lancet 379 (9822), 1214-1224, 2012 | 1082 | 2012 |
Genomewide association studies and human disease J Hardy, A Singleton New England Journal of Medicine 360 (17), 1759-1768, 2009 | 1031 | 2009 |