Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries M Kuljanin, DC Mitchell, DK Schweppe, AS Gikandi, DP Nusinow, ... Nature biotechnology 39 (5), 630-641, 2021 | 215 | 2021 |
Proteome-wide mapping of short-lived proteins in human cells J Li, Z Cai, LP Vaites, N Shen, DC Mitchell, EL Huttlin, JA Paulo, BL Harry, ... Molecular cell 81 (22), 4722-4735. e5, 2021 | 101 | 2021 |
A proteome-wide atlas of drug mechanism of action DC Mitchell, M Kuljanin, J Li, JG Van Vranken, N Bulloch, DK Schweppe, ... Nature biotechnology 41 (6), 845-857, 2023 | 74 | 2023 |
Assessing target engagement using proteome-wide solvent shift assays JG Van Vranken, J Li, DC Mitchell, J Navarrete-Perea, SP Gygi Elife 10, e70784, 2021 | 48 | 2021 |
The RNA-binding protein SART3 promotes miR-34a biogenesis and G1 cell cycle arrest in lung cancer cells EJ Sherman, DC Mitchell, AL Garner Journal of Biological Chemistry 294 (46), 17188-17196, 2019 | 25 | 2019 |
High-throughput chemical probing of full-length protein–protein interactions JM Song, A Menon, DC Mitchell, OT Johnson, AL Garner ACS combinatorial science 19 (12), 763-769, 2017 | 17 | 2017 |
The Arg/N-degron pathway targets transcription factors and regulates specific genes TTM Vu, DC Mitchell, SP Gygi, A Varshavsky Proceedings of the National Academy of Sciences 117 (49), 31094-31104, 2020 | 13 | 2020 |
Chemoproteomic profiling uncovers CDK4-mediated phosphorylation of the translational suppressor 4E-BP1 DC Mitchell, A Menon, AL Garner Cell chemical biology 26 (7), 980-990. e8, 2019 | 10 | 2019 |
Cyclin‐dependent kinase 4 inhibits the translational repressor 4E‐BP1 to promote cap‐dependent translation during mitosis–G1 transition DC Mitchell, A Menon, AL Garner FEBS letters 594 (8), 1307-1318, 2020 | 3 | 2020 |
The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway H Chen, CJ Ferguson, DC Mitchell, I Risch, A Titus, JA Paulo, A Hwang, ... Cell Reports 44 (2), 2025 | 2 | 2025 |
MNK-driven eIF4E phosphorylation regulates the fibrogenic transformation of mesenchymal cells and chronic lung allograft dysfunction NM Walker, Y Ibuki, AP McLinden, K Misumi, DC Mitchell, GG Kleer, ... The Journal of Clinical Investigation 134 (16), 2024 | 1 | 2024 |
Diet of three juvenile fish species of the coastal zone of a Southwest Atlantic beach, Brazil. JS Muniz Knoeller, A Ribeiro Gomes Tomás, T Vaske Junior Acta Scientiarum: Biological Sciences 44, 2022 | 1 | 2022 |
Synthetic Knockout Protein Standard for Evaluating Interference in Tandem Mass Tag-Based Proteomics J Navarrete-Perea, J Li, DC Mitchell, A Chi Analytical Chemistry 96 (17), 6836-6846, 2024 | | 2024 |
Highly specific intracellular ubiquitination of a small molecule W Li, EM Garcia-Rivera, DC Mitchell, JM Chick, M Maetani, JM Knapp, ... bioRxiv, 2024 | | 2024 |
Mnk Induced eiF4E Phosphorylation at Ser209 Plays a Critical Role in Fibrogenic Transformation of Graft-Resident Mesenchymal Cells and Pathogenesis of Bo Post-Lung Transplantation NM Walker, G Kleer, K Misumi, A Lock, D Mitchell, MP Combs, ... D77. TRANSPLANTATION, A7585-A7585, 2020 | | 2020 |
Development of a Chemoproteomic Approach to Study Kinase-Substrate Interactions and the Discovery of CDK4 as a 4E-BP1 Kinase D Mitchell | | 2019 |