Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome K Ure, H Lu, W Wang, A Ito-Ishida, Z Wu, L He, Y Sztainberg, W Chen, ... elife 5, e14198, 2016 | 119 | 2016 |
Manipulations of MeCP2 in glutamatergic neurons highlight their contributions to Rett and other neurological disorders X Meng, W Wang, H Lu, L He, W Chen, ES Chao, ML Fiorotto, B Tang, ... elife 5, e14199, 2016 | 112 | 2016 |
Otud7a knockout mice recapitulate many neurological features of 15q13. 3 microdeletion syndrome J Yin, W Chen, ES Chao, S Soriano, L Wang, W Wang, SE Cummock, ... The American Journal of Human Genetics 102 (2), 296-308, 2018 | 74 | 2018 |
Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy W Chen, ZL Cai, ES Chao, H Chen, CM Longley, S Hao, HT Chao, ... Elife 9, e48705, 2020 | 52 | 2020 |
Chrna7 deficient mice manifest no consistent neuropsychiatric and behavioral phenotypes J Yin, W Chen, H Yang, M Xue, CP Schaaf Scientific reports 7 (1), 39941, 2017 | 49 | 2017 |
A robust AUC maximization framework with simultaneous outlier detection and feature selection for positive-unlabeled classification K Ren, H Yang, Y Zhao, W Chen, M Xue, H Miao, S Huang, J Liu IEEE transactions on neural networks and learning systems 30 (10), 3072-3083, 2018 | 34 | 2018 |
Neurexophilin4 is a selectively expressed α-neurexin ligand that modulates specific cerebellar synapses and motor functions X Meng, CM McGraw, W Wang, J Jing, SY Yeh, L Wang, J Lopez, ... Elife 8, e46773, 2019 | 24 | 2019 |
Control of in vivo ictogenesis via endogenous synaptic pathways H Luna-Munguia, P Starski, W Chen, S Gliske, WC Stacey Scientific reports 7 (1), 1311, 2017 | 10 | 2017 |
Antisense oligonucleotide therapy rescues disturbed brain rhythms and sleep in juvenile and adult mouse models of Angelman syndrome D Lee, W Chen, HN Kaku, X Zhuo, ES Chao, A Soriano, A Kuncheria, ... Elife 12, e81892, 2023 | 8 | 2023 |
Kernel duration and modulation gain in a coupled oscillator model and their implications on the progression of seizures W Chen, DO Cahoy, JG Tasker, AWL Chiu Network: Computation in Neural Systems 23 (1-2), 59-75, 2012 | 4 | 2012 |
GABAergic/glycinergic and glutamatergic neurons mediate distinct neurodevelopmental phenotypes of STXBP1 encephalopathy JH Kim, W Chen, ES Chao, A Rivera, HN Kaku, K Jiang, D Lee, H Chen, ... Journal of Neuroscience 44 (14), 2024 | 1 | 2024 |
Glutamatergic and GABAergic neurons mediate distinct neurodevelopmental phenotypes of STXBP1 encephalopathy JH Kim, W Chen, ES Chao, H Chen, M Xue bioRxiv, 2021.07. 13.452234, 2021 | 1 | 2021 |
Gene therapy for stxbp1 encephalopathy XUE Mingshan, W Chen US Patent App. 18/004,194, 2023 | | 2023 |
Stxbp1/Munc18-1 haploinsufficiency in mice recapitulates key features of STXBP1 encephalopathy and impairs cortical inhibition W Chen, ZL Cai, ES Chao, H Chen, S Hao, HT Chao, JH Kim, JE Messier, ... bioRxiv, 621516, 2019 | | 2019 |
Steven E. Cummock, 2 Huifang Tao, Kaifang Pang, 2, 6 Zhandong Liu, 2, 6 Fred A. Pereira, 8, 9 Rodney C. Samaco, Huda Y. Zoghbi, Mingshan Xue, and Christian P. Schaaf J Yin, W Chen, ES Chao, S Soriano, L Wang, W Wang The American Journal of Human Genetics 102, 296-308, 2018 | | 2018 |
Author response: Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome K Ure, H Lu, W Wang, A Ito-Ishida, Z Wu, L He, Y Sztainberg, W Chen, ... Elife. 5, e15, 2016 | | 2016 |
Author response: Manipulations of MeCP2 in glutamatergic neurons highlight their contributions to Rett and other neurological disorders X Meng, W Wang, H Lu, L He, W Chen, ES Chao, ML Fiorotto, B Tang, ... Elife. 5, e20, 2016 | | 2016 |
Analysis of Glutamatergic and Gabaergic Receptor Dynamics in Coupled Oscillator Neural Model S Ramezani, W Chen, AWL Chiu International Journal of Modelling and Simulation 33 (3), 144-151, 2013 | | 2013 |
Oscillator-based neuronal modeling for seizure progression investigation and seizure control strategy W Chen Louisiana Tech University, 2012 | | 2012 |
CAP-002: Systemic AAV Gene Therapy with Next Generation Capsids for Treatment of STXBP1 Encephalopathy A Knoll, AJ Lopez, T Sandberg, B Wheeler, K Whitley, LS Grigoryeva, ... | | |