Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen AMJ Shapiro, JRT Lakey, EA Ryan, GS Korbutt, E Toth, GL Warnock, ... New England Journal of Medicine 343 (4), 230-238, 2000 | 6804 | 2000 |
International trial of the Edmonton protocol for islet transplantation AMJ Shapiro, C Ricordi, BJ Hering, H Auchincloss, R Lindblad, ... New England Journal of Medicine 355 (13), 1318-1330, 2006 | 2489 | 2006 |
Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol EA Ryan, JRT Lakey, RV Rajotte, GS Korbutt, T Kin, S Imes, ... Diabetes 50 (4), 710-719, 2001 | 1161 | 2001 |
Successful islet transplantation: continued insulin reserve provides long-term glycemic control EA Ryan, JRT Lakey, BW Paty, S Imes, GS Korbutt, NM Kneteman, ... Diabetes 51 (7), 2148-2157, 2002 | 1010 | 2002 |
Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages RM Seaberg, SR Smukler, TJ Kieffer, G Enikolopov, Z Asghar, ... Nature biotechnology 22 (9), 1115-1124, 2004 | 742 | 2004 |
Generation of insulin-producing islet-like clusters from human embryonic stem cells J Jiang, M Au, K Lu, A Eshpeter, G Korbutt, G Fisk, AS Majumdar Stem cells 25 (8), 1940-1953, 2007 | 663 | 2007 |
Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell–induced apoptosis B Motyka, G Korbutt, MJ Pinkoski, JA Heibein, A Caputo, M Hobman, ... Cell 103 (3), 491-500, 2000 | 576 | 2000 |
Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways K Cardona, GS Korbutt, Z Milas, J Lyon, J Cano, W Jiang, H Bello-Laborn, ... Nature medicine 12 (3), 304-306, 2006 | 557 | 2006 |
Glucose-dependent insulin release from genetically engineered K cells AT Cheung, B Dayanandan, JT Lewis, GS Korbutt, RV Rajotte, ... Science 290 (5498), 1959-1962, 2000 | 447 | 2000 |
Large scale isolation, growth, and function of porcine neonatal islet cells. GS Korbutt, JF Elliott, Z Ao, DK Smith, GL Warnock, RV Rajotte The Journal of clinical investigation 97 (9), 2119-2129, 1996 | 411 | 1996 |
Granzyme B: a natural born killer SJ Lord, RV Rajotte, GS Korbutt, RC Bleackley Immunological reviews 193 (1), 31-38, 2003 | 390 | 2003 |
Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta-cell function. DL Eizirik, GS Korbutt, C Hellerström The Journal of clinical investigation 90 (4), 1263-1268, 1992 | 383 | 1992 |
Islet graft assessment in the Edmonton Protocol: implications for predicting long-term clinical outcome CN Street, JRT Lakey, AMJ Shapiro, S Imes, RV Rajotte, EA Ryan, ... Diabetes 53 (12), 3107-3114, 2004 | 279 | 2004 |
Cotransplantation of allogeneic islets with allogeneic testicular cell aggregates allows long-term graft survival without systemic immunosuppression GS Korbutt, JF Elliott, RV Rajotte Diabetes 46 (2), 317-322, 1997 | 277 | 1997 |
Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destruction. A Rabinovitch, W Suarez-Pinzon, K Strynadka, Q Ju, D Edelstein, ... Diabetes 48 (6), 1223-1229, 1999 | 271 | 1999 |
Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion JRT Lakey, GL Warnock, AMJ Shapiro, GS Korbutt, Z Ao, NM Kneteman, ... Cell transplantation 8 (3), 285-292, 1999 | 254 | 1999 |
Insulin expressing cells from differentiated embryonic stem cells are not beta cells S Sipione, A Eshpeter, JG Lyon, GS Korbutt, RC Bleackley Diabetologia 47, 499-508, 2004 | 251 | 2004 |
Expansion of mesenchymal stem cells from human pancreatic ductal epithelium KL Seeberger, JM Dufour, AMJ Shapiro, JRT Lakey, RV Rajotte, ... Laboratory investigation 86 (2), 141-153, 2006 | 234 | 2006 |
Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts KJ Potter, A Abedini, P Marek, AM Klimek, S Butterworth, M Driscoll, ... Proceedings of the National Academy of Sciences 107 (9), 4305-4310, 2010 | 203 | 2010 |
Testicular sertoli cells protect islet beta-cells from autoimmune destruction in NOD mice by a transforming growth factor-beta1-dependent mechanism. W Suarez-Pinzon, GS Korbutt, R Power, J Hooton, RV Rajotte, ... Diabetes 49 (11), 1810-1818, 2000 | 178 | 2000 |