Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpefat mice DR Cool, E Normant, F Shen, HC Chen, L Pannell, Y Zhang, YP Loh Cell 88 (1), 73-83, 1997 | 506 | 1997 |
Chromogranin A, an “on/off” switch controlling dense-core secretory granule biogenesis T Kim, JH Tao-Cheng, LE Eiden, YP Loh Cell 106 (4), 499-509, 2001 | 493 | 2001 |
Aberrations in peripheral inflammatory cytokine levels in Parkinson disease: a systematic review and meta-analysis XY Qin, SP Zhang, C Cao, YP Loh, Y Cheng JAMA neurology 73 (11), 1316-1324, 2016 | 449 | 2016 |
The extended granin family: structure, function, and biomedical implications A Bartolomucci, R Possenti, SK Mahata, R Fischer-Colbrie, YP Loh, ... Endocrine reviews 32 (6), 755-797, 2011 | 360 | 2011 |
Proteolysis in neuropeptide processing and other neural functions YP Loh, MJ Brownstein, H Gainer Annual review of neuroscience 7 (1), 189-222, 1984 | 311 | 1984 |
Sorting and activity-dependent secretion of BDNF require interaction of a specific motif with the sorting receptor carboxypeptidase e H Lou, SK Kim, E Zaitsev, CR Snell, B Lu, YP Loh Neuron 45 (2), 245-255, 2005 | 231 | 2005 |
The enzymology and intracellular organization of peptide precursor processing: the secretory vesicle hypothesis H Gainer, JT Russell, YP Loh Neuroendocrinology 40 (2), 171-184, 1985 | 228 | 1985 |
Purification and characterization of a paired basic residue-specific pro-opiomelanocortin converting enzyme from bovine pituitary intermediate lobe secretory vesicles. YP Loh, DC Parish, R Tuteja Journal of Biological Chemistry 260 (12), 7194-7205, 1985 | 224 | 1985 |
Dense-core secretory granule biogenesis T Kim, MC Gondré-Lewis, I Arnaoutova, YP Loh Physiology 21 (2), 124-133, 2006 | 220 | 2006 |
The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake L Plum, HV Lin, R Dutia, J Tanaka, KS Aizawa, M Matsumoto, AJ Kim, ... Nature medicine 15 (10), 1195-1201, 2009 | 195 | 2009 |
Carboxypeptidase B-like converting enzyme activity in secretory granules of rat pituitary. VY Hook, YP Loh Proceedings of the National Academy of Sciences 81 (9), 2776-2780, 1984 | 191 | 1984 |
60 YEARS OF POMC: Biosynthesis, trafficking, and secretion of pro-opiomelanocortin-derived peptides NX Cawley, Z Li, YP Loh Journal of molecular endocrinology 56 (4), T77-T97, 2016 | 182 | 2016 |
Identification of the sorting signal motif within pro-opiomelanocortin for the regulated secretory pathway DR Cool, M Fenger, CR Snell, YP Loh Journal of Biological Chemistry 270 (15), 8723-8729, 1995 | 178 | 1995 |
Lipid raft association of carboxypeptidase E is necessary for its function as a regulated secretory pathway sorting receptor S Dhanvantari, YP Loh Journal of Biological Chemistry 275 (38), 29887-29893, 2000 | 150 | 2000 |
Characterization of pro-opiocortin-converting activity in purified secretory granules from rat pituitary neurointermediate lobe. YP Loh, H Gainer Proceedings of the National Academy of Sciences 79 (1), 108-112, 1982 | 142 | 1982 |
Decreased peripheral brain-derived neurotrophic factor levels in Alzheimer’s disease: a meta-analysis study (N= 7277) XY Qin, C Cao, NX Cawley, TT Liu, J Yuan, YP Loh, Y Cheng Molecular psychiatry 22 (2), 312-320, 2017 | 134 | 2017 |
Reengineered salivary glands are stable endogenous bioreactors for systemic gene therapeutics A Voutetakis, MR Kok, C Zheng, I Bossis, J Wang, AP Cotrim, N Marracino, ... Proceedings of the National Academy of Sciences 101 (9), 3053-3058, 2004 | 124 | 2004 |
The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits NX Cawley, J Zhou, JM Hill, D Abebe, S Romboz, T Yanik, RM Rodriguiz, ... Endocrinology 145 (12), 5807-5819, 2004 | 120 | 2004 |
New roles of carboxypeptidase E in endocrine and neural function and cancer NX Cawley, WC Wetsel, SRK Murthy, JJ Park, K Pacak, YP Loh Endocrine reviews 33 (2), 216-253, 2012 | 119 | 2012 |
Chromogranin A and derived peptides in health and disease YP Loh, Y Cheng, SK Mahata, A Corti, B Tota Journal of Molecular Neuroscience 48, 347-356, 2012 | 112 | 2012 |