Resolving medulloblastoma cellular architecture by single-cell genomics V Hovestadt, KS Smith, L Bihannic, MG Filbin, MKL Shaw, A Baumgartner, ... Nature 572 (7767), 74-79, 2019 | 359 | 2019 |
Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes T Sharma, EC Schwalbe, D Williamson, M Sill, V Hovestadt, M Mynarek, ... Acta neuropathologica 138, 309-326, 2019 | 260 | 2019 |
Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial GW Robinson, VA Rudneva, I Buchhalter, CA Billups, SM Waszak, ... The Lancet Oncology 19 (6), 768-784, 2018 | 216 | 2018 |
H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers A Korshunov, D Schrimpf, M Ryzhova, D Sturm, L Chavez, V Hovestadt, ... Acta neuropathologica 134, 507-516, 2017 | 197 | 2017 |
Aberrant ERBB4-SRC signaling as a hallmark of group 4 medulloblastoma revealed by integrative phosphoproteomic profiling A Forget, L Martignetti, S Puget, L Calzone, S Brabetz, D Picard, ... Cancer cell 34 (3), 379-395. e7, 2018 | 145 | 2018 |
Germline elongator mutations in sonic hedgehog medulloblastoma SM Waszak, GW Robinson, BL Gudenas, KS Smith, A Forget, M Kojic, ... Nature 580 (7803), 396-401, 2020 | 134 | 2020 |
Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis A Korshunov, L Chavez, T Sharma, M Ryzhova, D Schrimpf, D Stichel, ... Brain pathology 28 (5), 656-662, 2018 | 120 | 2018 |
Heterogeneity within the PF-EPN-B ependymoma subgroup FMG Cavalli, JM Hübner, T Sharma, B Luu, M Sill, M Zapotocky, SC Mack, ... Acta neuropathologica 136, 227-237, 2018 | 109 | 2018 |
Integrated molecular characterization of IDH‐mutant glioblastomas A Korshunov, B Casalini, L Chavez, T Hielscher, M Sill, M Ryzhova, ... Neuropathology and applied neurobiology 45 (2), 108-118, 2019 | 89 | 2019 |
YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis KW Pajtler, Y Wei, K Okonechnikov, PBG Silva, M Vouri, L Zhang, ... Nature communications 10 (1), 3914, 2019 | 86 | 2019 |
Nonmetastatic medulloblastoma of early childhood: results from the prospective clinical trial HIT-2000 and an extended validation cohort M Mynarek, K von Hoff, T Pietsch, H Ottensmeier, M Warmuth-Metz, ... Journal of clinical oncology 38 (18), 2028-2040, 2020 | 84 | 2020 |
H3. 3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model D Haag, N Mack, PBG da Silva, B Statz, J Clark, K Tanabe, T Sharma, ... Cancer cell 39 (3), 407-422. e13, 2021 | 77 | 2021 |
Germline GPR161 Mutations Predispose to Pediatric Medulloblastoma M Begemann, SM Waszak, GW Robinson, N Jäger, T Sharma, C Knopp, ... Journal of Clinical Oncology 38 (1), 43-50, 2020 | 62 | 2020 |
A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors JE Neumann, AK Wefers, S Lambo, E Bianchi, M Bockstaller, ... Nature medicine 23 (10), 1191-1202, 2017 | 51 | 2017 |
DNA-methylation profiling discloses significant advantages over NanoString method for molecular classification of medulloblastoma A Korshunov, L Chavez, PA Northcott, T Sharma, M Ryzhova, DTW Jones, ... Acta neuropathologica 134, 965-967, 2017 | 44 | 2017 |
Nucleosome repositioning during differentiation of a human myeloid leukemia cell line VB Teif, JP Mallm, T Sharma, DB Mark Welch, K Rippe, R Eils, ... Nucleus 8 (2), 188-204, 2017 | 22 | 2017 |
Genetic confirmation that ependymoma can arise as part of multiple endocrine neoplasia type 1 (MEN1) syndrome AK Cuevas-Ocampo, AW Bollen, B Goode, KW Pajtler, L Chavez, ... Acta neuropathologica 133, 661-663, 2017 | 16 | 2017 |
Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes T Sharma, EC Schwalbe, DW Williamson, M Sill, V Hovestadt, M Mynarek, ... CANCER RESEARCH 80 (14), 117-117, 2020 | 2 | 2020 |
MBCL-21. EARLY CHILDHOOD MEDULLOBLASTOMA: SUBGROUP-SPECIFIC SURVIVAL IN PATIENTS TREATED WITH SYSTEMIC CHEMOTHERAPY AND INTRAVENTRICULAR MTX TO AVOID CRANIOSPINAL RADIOTHERAPY M Mynarek, M Kool, U Schueller, K von Hoff, T Sharma, V Rudneva, ... Neuro-Oncology 20 (suppl_2), i121-i121, 2018 | 1 | 2018 |
MBCL-07. NON-METASTATIC MEDULLOBLASTOMA OF EARLY CHILDHOOD: RESULTS FROM THE PROSPECTIVE CLINICAL TRIAL HIT-2000 AND AN EXTENDED VALIDATION COHORT M Mynarek, K von Hoff, T Pietsch, H Ottensmeier, M Warmuth-Metz, ... Neuro-oncology 22 (Supplement_3), iii388-iii389, 2020 | | 2020 |