Autophagy dysregulation in ALS: when protein aggregates get out of hand N Ramesh, UB Pandey Frontiers in molecular neuroscience 10, 263, 2017 | 190 | 2017 |
The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity V Crippa, ME Cicardi, N Ramesh, SJ Seguin, M Ganassi, I Bigi, C Diacci, ... Human Molecular Genetics 25 (18), 3908-3924, 2016 | 87 | 2016 |
Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway YC Lin, MS Kumar, N Ramesh, EN Anderson, AT Nguyen, B Kim, ... Nature neuroscience 24 (8), 1077-1088, 2021 | 70 | 2021 |
Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity JG Daigle, K Krishnamurthy, N Ramesh, I Casci, J Monaghan, K McAvoy, ... Acta neuropathologica 131, 605-620, 2016 | 64 | 2016 |
Mutations in TGM6 induce the unfolded protein response in SCA35 D Tripathy, B Vignoli, N Ramesh, MJ Polanco, M Coutelier, CD Stephen, ... Human molecular genetics 26 (19), 3749-3762, 2017 | 46 | 2017 |
Mutation-dependent aggregation and toxicity in a Drosophila model for UBQLN2-associated ALS SH Kim, SG Stiles, JM Feichtmeier, N Ramesh, L Zhan, MA Scalf, ... Human molecular genetics 27 (2), 322-337, 2018 | 41 | 2018 |
RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM N Ramesh, S Kour, EN Anderson, D Rajasundaram, UB Pandey Acta neuropathologica communications 8, 1-22, 2020 | 39 | 2020 |
Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo N Gogia, A Sarkar, AS Mehta, N Ramesh, P Deshpande, M Kango-Singh, ... Neurobiology of disease 140, 104837, 2020 | 38 | 2020 |
Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology EN Anderson, AA Morera, S Kour, JD Cherry, N Ramesh, A Gleixner, ... Elife 10, e67587, 2021 | 36 | 2021 |
NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility AM Gleixner, BM Verdone, CG Otte, EN Anderson, N Ramesh, ... Nature communications 13 (1), 3380, 2022 | 31 | 2022 |
Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization I Casci, K Krishnamurthy, S Kour, V Tripathy, N Ramesh, EN Anderson, ... Nature Communications 10 (1), 5583, 2019 | 31 | 2019 |
RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3 N Ramesh, EL Daley, AM Gleixner, JR Mann, S Kour, D Mawrie, ... Acta Neuropathologica Communications 8, 1-20, 2020 | 22 | 2020 |
Optogenetic TDP-43 nucleation induces persistent insoluble species and progressive motor dysfunction in vivo CG Otte, TR Fortuna, JR Mann, AM Gleixner, N Ramesh, NJ Pyles, ... Neurobiology of disease 146, 105078, 2020 | 11 | 2020 |
Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer’s disease AR Agra Almeida Quadros, Z Li, X Wang, IS Ndayambaje, S Aryal, ... Acta neuropathologica 147 (1), 9, 2024 | 9 | 2024 |
Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand. Front Mol Neurosci 10, 263 N Ramesh, UB Pandey | 9 | 2017 |
Axon guidance genes modulate neurotoxicity of ALS-associated UBQLN2 SH Kim, KD Nichols, EN Anderson, Y Liu, N Ramesh, W Jia, CJ Kuerbis, ... Elife 12, e84382, 2023 | 5 | 2023 |
Nup62 is recruited to pathological condensates and promotes TDP-43 insolubility in C9orf72 and sporadic ALS/FTLD. A Gleixner, BM Verdone, C Otte, N Ramesh, J Gale, J Mauna, J Mann, ... | 1 | 2021 |
Axon guidance pathways modulate neurotoxicity of ALS-associated UBQLN2 SH Kim, KD Nichols, EN Anderson, Y Liu, N Ramesh, W Jia, CJ Kuerbis, ... bioRxiv, 2022.10. 31.514355, 2022 | | 2022 |
Investigating the Role of Matrin-3 in Amyotrophic Lateral Sclerosis and Distal Myopathy N Ramesh University of Pittsburgh, 2020 | | 2020 |