| Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers E Mullarky, NC Lucki, R Beheshti Zavareh, JL Anglin, AP Gomes, ... Proceedings of the National Academy of Sciences 113 (7), 1778-1783, 2016 | 318 | 2016 |
| The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma GW Xu, M Ali, TE Wood, D Wong, N Maclean, X Wang, M Gronda, M Skrtic, ... Blood, The Journal of the American Society of Hematology 115 (11), 2251-2259, 2010 | 198 | 2010 |
| The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma PA Spagnuolo, J Hu, R Hurren, X Wang, M Gronda, MA Sukhai, A Di Meo, ... Blood, The Journal of the American Society of Hematology 115 (23), 4824-4833, 2010 | 180 | 2010 |
| Inhibition of the sodium potassium adenosine triphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation CD Simpson, IA Mawji, K Anyiwe, MA Williams, X Wang, AL Venugopal, ... Cancer research 69 (7), 2739-2747, 2009 | 121 | 2009 |
| Eyelid masses: a 10-year survey from a tertiary eye hospital in Tehran A Bagheri, M Tavakoli, A Kanaani, RB Zavareh, H Esfandiari, M Aletaha, ... Middle East African Journal of Ophthalmology 20 (3), 187-192, 2013 | 82 | 2013 |
| Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function RB Zavareh, KS Lau, R Hurren, A Datti, DJ Ashline, M Gronda, P Cheung, ... Cancer research 68 (16), 6688-6697, 2008 | 73 | 2008 |
| HSP90 inhibition enhances cancer immunotherapy by modulating the surface expression of multiple immune checkpoint proteins RB Zavareh, SH Spangenberg, A Woods, F Martínez-Peña, LL Lairson Cell chemical biology 28 (2), 158-168. e5, 2021 | 62 | 2021 |
| Cyproheptadine displays preclinical activity in myeloma and leukemia X Mao, S Liang, R Hurren, M Gronda, S Chow, GW Xu, X Wang, ... Blood, The Journal of the American Society of Hematology 112 (3), 760-769, 2008 | 61 | 2008 |
| Discovery of small molecules for the reversal of T cell exhaustion BS Marro, J Zak, RB Zavareh, JR Teijaro, LL Lairson, MBA Oldstone Cell reports 29 (10), 3293-3302. e3, 2019 | 50 | 2019 |
| Suppression of cancer progression by MGAT1 shRNA knockdown R Beheshti Zavareh, MA Sukhai, R Hurren, M Gronda, X Wang, ... Public Library of Science 7 (9), e43721, 2012 | 46 | 2012 |
| Involvement of ApoE E4 and H63D in sporadic Alzheimer's disease in a folate-supplemented Ontario population M Percy, S Moalem, A Garcia, MJ Somerville, M Hicks, D Andrews, ... Journal of Alzheimer's Disease 14 (1), 69-84, 2008 | 38 | 2008 |
| Biochemical characterization and structure-based mutational analysis provide insight into the binding and mechanism of action of novel aspartate aminotransferase inhibitors MC Holt, Z Assar, R Beheshti Zavareh, L Lin, J Anglin, O Mashadova, ... Biochemistry 57 (47), 6604-6614, 2018 | 36 | 2018 |
| Discovery and optimization of aspartate aminotransferase 1 inhibitors to target redox balance in pancreatic ductal adenocarcinoma J Anglin, RB Zavareh, PN Sander, D Haldar, E Mullarky, LC Cantley, ... Bioorganic & medicinal chemistry letters 28 (16), 2675-2678, 2018 | 33 | 2018 |
| JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma J Zak, I Pratumchai, BS Marro, KL Marquardt, RB Zavareh, LL Lairson, ... Science 384 (6702), eade8520, 2024 | 28 | 2024 |
| Molecular characterization of type I IFN-induced cytotoxicity in bladder cancer cells reveals biomarkers of resistance JL Green, RE Osterhout, AL Klova, C Merkwirth, SRP McDonnell, ... Molecular Therapy-Oncolytics 23, 547-559, 2021 | 12 | 2021 |
| A novel diquinolonium displays preclinical anti-cancer activity and induces caspase-independent cell death R Hurren, RB Zavareh, S Dalili, T Wood, D Rose, H Chang, N Jamal, ... Apoptosis 13, 748-755, 2008 | 11 | 2008 |
| Sequential, cycling maintenance therapy for post transplant multiple myeloma CI Chen, S Nanji, A Prabhu, R Beheshti, QL Yi, D Sutton, AK Stewart Bone marrow transplantation 37 (1), 89-94, 2006 | 8 | 2006 |
| Identification of small-molecule protein–protein interaction inhibitors for NKG2D AA Thompson, MB Harbut, PP Kung, NK Karpowich, JD Branson, ... Proceedings of the National Academy of Sciences 120 (18), e2216342120, 2023 | 7 | 2023 |
| Protocol for high-throughput compound screening using flow cytometry in THP-1 cells SH Spangenberg, RB Zavareh, LL Lairson STAR protocols 2 (2), 100400, 2021 | 6 | 2021 |
| Discovery and development of a selective inhibitor of the ER resident chaperone Grp78 AJ Ambrose, J Sivinski, CJ Zerio, X Zhu, J Godek, VK Kumirov, ... Journal of Medicinal Chemistry 66 (1), 677-694, 2022 | 5 | 2022 |
Luke LairsonThe Scripps Research Institute在 scripps.edu 的电子邮件经过验证
