Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants C MacKintosh, KA Beattie, S Klumpp, P Cohen, GA Codd FEBS letters 264 (2), 187-192, 1990 | 2041 | 1990 |
Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity J Liu, MW Albers, TJ Wandless, S Luan, DG Alberg, PJ Belshaw, P Cohen, ... Biochemistry 31 (16), 3896-3901, 1992 | 736 | 1992 |
Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes C Mackintosh Biochemical Journal 381 (2), 329-342, 2004 | 629 | 2004 |
14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking MP Rubio, KM Geraghty, BHC Wong, NT Wood, DG Campbell, N Morrice, ... Biochemical Journal 379 (2), 395-408, 2004 | 543 | 2004 |
Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1 CI Holmberg, V Hietakangas, A Mikhailov, JO Rantanen, M Kallio, ... The EMBO journal, 2001 | 427 | 2001 |
Bioinformatic and experimental survey of 14-3-3-binding sites C Johnson, S Crowther, MJ Stafford, DG Campbell, R Toth, C MacKintosh Biochemical Journal 427 (1), 69-78, 2010 | 390 | 2010 |
The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1 RW MacKintosh, KN Dalby, DG Campbell, PTW Cohen, P Cohen, ... FEBS letters 371 (3), 236-240, 1995 | 376 | 1995 |
AMP‐activated protein kinase: a cellular energy sensor that comes in 12 flavours FA Ross, C MacKintosh, DG Hardie The FEBS journal 283 (16), 2987-3001, 2016 | 361 | 2016 |
Inhibitors of protein kinases and phosphatases C MacKintosh, RW MacKintosh Trends in biochemical sciences 19 (11), 444-448, 1994 | 353 | 1994 |
Phosphorylation‐dependent interactions between enzymes of plant metabolism and 14‐3‐3 proteins G Moorhead, P Douglas, V Cotelle, J Harthill, N Morrice, S Meek, ... The Plant Journal 18 (1), 1-12, 1999 | 336 | 1999 |
PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex BD Fonseca, EM Smith, VHY Lee, C MacKintosh, CG Proud Journal of Biological Chemistry 282 (34), 24514-24524, 2007 | 298 | 2007 |
Phosphorylated nitrate reductase from spinach leaves is inhibited by 14-3-3 proteins and activated by fusicoccin G Moorhead, P Douglas, N Morrice, M Scarabel, A Aitken, C MacKintosh Current Biology 6 (9), 1104-1113, 1996 | 288 | 1996 |
Tautomycin from the bacterium Streptomyces verticillatus Another potent and specific inhibitor of protein phosphatases 1 and 2A C MacKintosh, S Klumpp FEBS letters 277 (1-2), 137-140, 1990 | 261 | 1990 |
Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators S Chen, J Murphy, R Toth, DG Campbell, NA Morrice, C Mackintosh Biochemical Journal 409 (2), 449-459, 2008 | 250 | 2008 |
Modulators of 14-3-3 protein–protein interactions LM Stevers, E Sijbesma, M Botta, C MacKintosh, T Obsil, I Landrieu, ... Journal of medicinal chemistry 61 (9), 3755-3778, 2017 | 246 | 2017 |
14‐3‐3s regulate global cleavage of their diverse binding partners in sugar‐starved Arabidopsis cells V Cotelle, SEM Meek, F Provan, FC Milne, N Morrice, C MacKintosh The EMBO Journal, 2000 | 244 | 2000 |
Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR KM Geraghty, S Chen, JE Harthill, AF Ibrahim, R Toth, NA Morrice, ... Biochemical Journal 407 (2), 231-241, 2007 | 230 | 2007 |
14-3-3-Pred: Improved methods to predict 14-3-3-binding phosphopeptides. BGJ Madeira F, Tinti M, Murugesan G, Berrett E, Stafford M, Toth R, Cole C ... bioinformatics, 2015 | 204 | 2015 |
Phosphorylation and 14‐3‐3 binding of Arabidopsis trehalose‐phosphate synthase 5 in response to 2‐deoxyglucose JE Harthill, SEM Meek, N Morrice, MW Peggie, J Borch, BHC Wong, ... The Plant Journal 47 (2), 211-223, 2006 | 202 | 2006 |
Genetic disruption of AMPK signaling abolishes both contraction-and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle C Pehmøller, JT Treebak, JB Birk, S Chen, C MacKintosh, DG Hardie, ... American Journal of Physiology-Endocrinology and Metabolism 297 (3), E665-E675, 2009 | 199 | 2009 |