Aminopeptidase N (CD13) as a target for cancer chemotherapy M Wickström, R Larsson, P Nygren, J Gullbo Cancer science 102 (3), 501-508, 2011 | 383 | 2011 |
Neuroblastoma—a neural crest derived embryonal malignancy JI Johnsen, C Dyberg, M Wickström Frontiers in molecular neuroscience 12, 9, 2019 | 252 | 2019 |
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance M Wickström, C Dyberg, J Milosevic, C Einvik, R Calero, ... Nature communications 6 (1), 8904, 2015 | 227 | 2015 |
Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo M Wickström, C Dyberg, T Shimokawa, J Milosevic, N Baryawno, ... International journal of cancer 132 (7), 1516-1524, 2013 | 143 | 2013 |
Pharmacological profiling of disulfiram using human tumor cell lines and human tumor cells from patients M Wickström, K Danielsson, L Rickardson, J Gullbo, P Nygren, A Isaksson, ... Biochemical pharmacology 73 (1), 25-33, 2007 | 139 | 2007 |
Cytotoxic effects of cardiac glycosides in colon cancer cells, alone and in combination with standard chemotherapeutic drugs J Felth, L Rickardson, J Rosén, M Wickstrom, M Fryknäs, M Lindskog, ... Journal of natural products 72 (11), 1969-1974, 2009 | 127 | 2009 |
Inhibitors and promoters of tubulin polymerization: Synthesis and biological evaluation of chalcones and related dienones as potential anticancer agents C Dyrager, M Wickström, M Fridén-Saxin, A Friberg, K Dahlén, ... Bioorganic & medicinal chemistry 19 (8), 2659-2665, 2011 | 98 | 2011 |
High content screening for inhibitors of protein interactions and post-translational modifications in primary cells by proximity ligation KJ Leuchowius, M Jarvius, M Wickström, L Rickardson, U Landegren, ... Molecular & Cellular Proteomics 9 (1), 178-183, 2010 | 90 | 2010 |
Effects of small molecule inhibitors of PI3K/Akt/mTOR signaling on neuroblastoma growth in vitro and in vivo L Segerström, N Baryawno, B Sveinbjörnsson, M Wickström, L Elfman, ... International journal of cancer 129 (12), 2958-2965, 2011 | 88 | 2011 |
Celecoxib Prevents Neuroblastoma Tumor Development and Potentiates the Effect of Chemotherapeutic Drugs In vitro and In vivo F Ponthan, M Wickström, H Gleissman, OM Fuskevåg, L Segerström, ... Clinical cancer research 13 (3), 1036-1044, 2007 | 88 | 2007 |
Melflufen-a peptidase-potentiated alkylating agent in clinical trials M Wickström, P Nygren, R Larsson, J Harmenberg, J Lindberg, P Sjöberg, ... Oncotarget 8 (39), 66641, 2017 | 87 | 2017 |
Molecular mechanisms and therapeutic targets in neuroblastoma JI Johnsen, C Dyberg, S Fransson, M Wickström Pharmacological research 131, 164-176, 2018 | 73 | 2018 |
Rho-associated kinase is a therapeutic target in neuroblastoma C Dyberg, S Fransson, T Andonova, B Sveinbjörnsson, ... Proceedings of the National Academy of Sciences 114 (32), E6603-E6612, 2017 | 71 | 2017 |
The alkylating prodrug J1 can be activated by aminopeptidase N, leading to a possible target directed release of melphalan M Wickström, K Viktorsson, L Lundholm, R Aesoy, H Nygren, L Sooman, ... Biochemical pharmacology 79 (9), 1281-1290, 2010 | 63 | 2010 |
Image-based screening for the identification of novel proteasome inhibitors L Rickardson, M Wickström, R Larsson, H Lövborg Journal of biomolecular screening 12 (2), 203-210, 2007 | 61 | 2007 |
Protective role of humanin on bortezomib-induced bone growth impairment in anticancer treatment E Eriksson, M Wickström, LS Perup, JI Johnsen, S Eksborg, P Kogner, ... Journal of the National Cancer Institute 106 (3), djt459, 2014 | 55 | 2014 |
Activity of Hydrolytic Enzymes in Tumour Cells is a Determinant for Anti-tumour Efficacy of the Melphalan Containing Prodrug J1 J Gullbo, M Wickström, M Tullberg, H Ehrsson, R Lewensohn, P Nygren, ... Journal of drug targeting 11 (6), 355-363, 2003 | 53 | 2003 |
Inhibition of chemerin/CMKLR1 axis in neuroblastoma cells reduces clonogenicity and cell viability in vitro and impairs tumor growth in vivo C Tümmler, I Snapkov, M Wickström, U Moens, L Ljungblad, LHM Elfman, ... Oncotarget 8 (56), 95135, 2017 | 49 | 2017 |
The cytotoxic agents NSC-95397, brefeldin A, bortezomib and sanguinarine induce apoptosis in neuroendocrine tumors in vitro DE Larsson, M Wickström, S Hassan, K Öberg, DAN Granberg Anticancer research 30 (1), 149-156, 2010 | 49 | 2010 |
Simvastatin induces apoptosis in human breast cancer cells in a NFκB-dependent manner and abolishes the anti-apoptotic signaling of TF/FVIIa and TF/FVIIa/FXa M Åberg, M Wickström, A Siegbahn Thrombosis research 122 (2), 191-202, 2008 | 49 | 2008 |