Structure, activation and dysregulation of fibroblast growth factor receptor kinases: perspectives for clinical targeting B Farrell, AL Breeze Biochemical Society Transactions 46 (6), 1753-1770, 2018 | 102 | 2018 |
Disease variants of FGFR3 reveal molecular basis for the recognition and additional roles for Cdc37 in Hsp90 chaperone system TD Bunney, AJ Inglis, D Sanfelice, B Farrell, CJ Kerr, GS Thompson, ... Structure 26 (3), 446-458. e8, 2018 | 18 | 2018 |
The PfRCR complex bridges malaria parasite and erythrocyte during invasion B Farrell, N Alam, MN Hart, A Jamwal, RJ Ragotte, H Walters-Morgan, ... Nature 625 (7995), 578-584, 2024 | 13 | 2024 |
Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5 LT Wang, AJR Cooper, B Farrell, K Miura, A Diouf, N Müller-Sienerth, ... Cell 187 (18), 4981-4995. e14, 2024 | 6 | 2024 |
NMR backbone assignments of the tyrosine kinase domain of human fibroblast growth factor receptor 3 in apo state and in complex with inhibitor PD173074 D Sanfelice, H Koss, TD Bunney, GS Thompson, B Farrell, M Katan, ... Biomolecular NMR Assignments 12, 231-235, 2018 | 3 | 2018 |
Structure of the PfRCR complex which bridges the malaria parasite and erythrocyte during invasion B Farrell, N Alam, MN Hart, A Jamwal, RJ Ragotte, H Walters-Morgan, ... bioRxiv, 2023.01. 30.526221, 2023 | 2 | 2023 |
Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5 TE Harrison, N Alam, B Farrell, D Quinkert, AM Lias, LDW King, LK Barfod, ... EMBO Molecular Medicine 16 (10), 2539-2559, 2024 | 1 | 2024 |
Cell-free expression and SMA copolymer encapsulation of a functional receptor tyrosine kinase disease variant, FGFR3-TACC3 AJD Snow, T Wijesiriwardena, BJ Lane, B Farrell, PC Dowdle, M Katan, ... bioRxiv, 2024.06. 04.596442, 2024 | | 2024 |
Exploring the mechanisms of Fibroblast Growth Factor Receptor activation and regulation using structural tools B Farrell University of Leeds, 2019 | | 2019 |
Structure, activation and dysregulation of fibroblast growth factor receptor kinases: perspectives for B Farrell, AL Breeze ARQ 108, 610, 0 | | |