Activation and regulation of purinergic P2X receptor channels C Coddou, Z Yan, T Obsil, JP Huidobro-Toro, SS Stojilkovic Pharmacological reviews 63 (3), 641-683, 2011 | 616 | 2011 |
Crystal structure of the 14-3-3ζ: serotonin N-acetyltransferase complex: a role for scaffolding in enzyme regulation T Obsil, R Ghirlando, DC Klein, S Ganguly, F Dyda Cell 105 (2), 257-267, 2001 | 488 | 2001 |
Structural basis of 14-3-3 protein functions T Obsil, V Obsilova Seminars in cell & developmental biology 22 (7), 663-672, 2011 | 351 | 2011 |
Structure/function relationships underlying regulation of FOXO transcription factors T Obsil, V Obsilova Oncogene 27 (16), 2263-2275, 2008 | 337 | 2008 |
Modulators of 14-3-3 protein–protein interactions LM Stevers, E Sijbesma, M Botta, C MacKintosh, T Obsil, I Landrieu, ... Journal of medicinal chemistry 61 (9), 3755-3778, 2017 | 256 | 2017 |
Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis S Ganguly, JA Gastel, JL Weller, C Schwartz, H Jaffe, MAA Namboodiri, ... Proceedings of the National Academy of Sciences 98 (14), 8083-8088, 2001 | 202 | 2001 |
14-3-3 proteins: a family of versatile molecular regulators V Obšlova, J Šilhan, E BouŔa, J Teisinger, T Obšil Physiol Res, S11-S21, 2008 | 190 | 2008 |
14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4 V Obsilova, J Vecer, P Herman, A Pabianova, M Sulc, J Teisinger, ... Biochemistry 44 (34), 11608-11617, 2005 | 168 | 2005 |
Two 14-3-3 binding motifs are required for stable association of Forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding T Obsil, R Ghirlando, DE Anderson, AB Hickman, F Dyda Biochemistry 42 (51), 15264-15272, 2003 | 145 | 2003 |
Structural basis for DNA recognition by FOXO proteins T Obsil, V Obsilova Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (11), 1946-1953, 2011 | 121 | 2011 |
14-3-3ζ C-terminal stretch changes its conformation upon ligand binding and phosphorylation at Thr232 V Obsilova, P Herman, J Vecer, M Sulc, J Teisinger, T Obsil Journal of Biological Chemistry 279 (6), 4531-4540, 2004 | 114 | 2004 |
Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner K Valis, L Prochazka, E Boura, J Chladova, T Obsil, J Rohlena, J Truksa, ... Cancer research 71 (3), 946-954, 2011 | 110 | 2011 |
Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding E Boura, J Silhan, P Herman, J Vecer, M Sulc, J Teisinger, V Obsilova, ... Journal of Biological Chemistry 282 (11), 8265-8275, 2007 | 101 | 2007 |
A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation H Zhao, R Ghirlando, C Alfonso, F Arisaka, I Attali, DL Bain, MM Bakhtina, ... PloS one 10 (5), e0126420, 2015 | 98 | 2015 |
Mechanisms of the 14-3-3 protein function: regulation of protein function through conformational modulation. V Obsilova, M Kopecka, D Kosek, M Kacirova, S Kylarova, L Rezabkova, ... Physiological research 63, 2014 | 96 | 2014 |
14-3-3 protein C-terminal stretch occupies ligand binding groove and is displaced by phosphopeptide binding J Silhan, V Obsilova, J Vecer, P Herman, M Sulc, J Teisinger, T Obsil Journal of Biological Chemistry 279 (47), 49113-49119, 2004 | 87 | 2004 |
Structure of the human FOXO4-DBD–DNA complex at 1.9 Å resolution reveals new details of FOXO binding to the DNA E Boura, L Rezabkova, J Brynda, V Obsilova, T Obsil Acta Crystallographica Section D: Biological Crystallography 66 (12), 1351-1357, 2010 | 83 | 2010 |
14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4 J Silhan, P Vacha, P Strnadova, J Vecer, P Herman, M Sulc, J Teisinger, ... Journal of Biological Chemistry 284 (29), 19349-19360, 2009 | 81 | 2009 |
14-3-3 Proteins and photoneuroendocrine transduction: role in controlling the daily rhythm in melatonin DC Klein, S Ganguly, S Coon, JL Weller, T Obsil, A Hickman, F Dyda Biochemical Society Transactions 30 (4), 365-373, 2002 | 81 | 2002 |
Identification of P2X4 receptor transmembrane residues contributing to channel gating and interaction with ivermectin I Jelínkova, V Vávra, M Jindrichova, T Obsil, HW Zemkova, H Zemkova, ... Pflügers Archiv-European Journal of Physiology 456, 939-950, 2008 | 79 | 2008 |