A randomized placebo-controlled trial of idebenone in Leber’s hereditary optic neuropathy T Klopstock, P Yu-Wai-Man, K Dimitriadis, J Rouleau, S Heck, M Bailie, ... Brain 134 (9), 2677-2686, 2011 | 583 | 2011 |
Efficacy of idebenone on respiratory function in patients with Duchenne muscular dystrophy not using glucocorticoids (DELOS): a double-blind randomised placebo-controlled phase … GM Buyse, T Voit, U Schara, CSM Straathof, MG D'Angelo, G Bernert, ... The Lancet 385 (9979), 1748-1757, 2015 | 224 | 2015 |
Characterization of pulmonary function in Duchenne muscular dystrophy OH Mayer, RS Finkel, C Rummey, MJ Benton, AM Glanzman, J Flickinger, ... Pediatric pulmonology 50 (5), 487-494, 2015 | 171 | 2015 |
Idebenone in Friedreich ataxia cardiomyopathy—results from a 6-month phase III study (IONIA) SJ Lagedrost, MSJ Sutton, MS Cohen, GM Satou, BD Kaufman, ... American heart journal 161 (3), 639-645. e1, 2011 | 159 | 2011 |
The heart in Friedreich ataxia: definition of cardiomyopathy, disease severity, and correlation with neurological symptoms F Weidemann, C Rummey, B Bijnens, S Störk, R Jasaityte, J Dhooge, ... Circulation 125 (13), 1626-1634, 2012 | 147 | 2012 |
Peroxomolybdenum complexes as epoxidation catalysts in biphasic hydrogen peroxide activation: raman spectroscopic studies and density functional calculations G Wahl, D Kleinhenz, A Schorm, J Sundermeyer, R Stowasser, ... Chemistry–A European Journal 5 (11), 3237-3251, 1999 | 118 | 1999 |
Features of idebenone and related short-chain quinones that rescue ATP levels under conditions of impaired mitochondrial complex I M Erb, B Hoffmann-Enger, H Deppe, M Soeberdt, RH Haefeli, C Rummey, ... PloS one 7 (4), e36153, 2012 | 117 | 2012 |
Assessment of neurological efficacy of idebenone in pediatric patients with Friedreich's ataxia: data from a 6-month controlled study followed by a 12-month open-label … T Meier, SL Perlman, C Rummey, NJ Coppard, DR Lynch Journal of neurology 259, 284-291, 2012 | 114 | 2012 |
Effects of idebenone on color vision in patients with leber hereditary optic neuropathy G Rudolph, K Dimitriadis, B Büchner, S Heck, J Al-Tamami, ... Journal of Neuro-Ophthalmology 33 (1), 30-36, 2013 | 112 | 2013 |
3D QSAR investigations on antimalarial naphthylisoquinoline alkaloids by comparative molecular similarity indices analysis (CoMSIA), based on different alignment approaches G Bringmann, C Rummey Journal of chemical information and computer sciences 43 (1), 304-316, 2003 | 91 | 2003 |
Idebenone reduces respiratory complications in patients with Duchenne muscular dystrophy CM McDonald, T Meier, T Voit, U Schara, CSM Straathof, MG D'Angelo, ... Neuromuscular Disorders 26 (8), 473-480, 2016 | 82 | 2016 |
Progression characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS): a 4-year cohort study K Reetz, I Dogan, RD Hilgers, P Giunti, MH Parkinson, C Mariotti, ... The Lancet Neurology 20 (5), 362-372, 2021 | 71 | 2021 |
Homology models of dipeptidyl peptidases 8 and 9 with a focus on loop predictions near the active site C Rummey, G Metz Proteins: Structure, Function, and Bioinformatics 66 (1), 160-171, 2007 | 71 | 2007 |
Psychometric properties of the Friedreich ataxia rating scale C Rummey, LA Corben, MB Delatycki, SH Subramony, K Bushara, ... Neurology: Genetics 5 (6), 371, 2019 | 70 | 2019 |
In silico fragment-based discovery of DPP-IV S1 pocket binders C Rummey, S Nordhoff, M Thiemann, G Metz Bioorganic & medicinal chemistry letters 16 (5), 1405-1409, 2006 | 68 | 2006 |
Characterization of pulmonary function in 10–18 year old patients with Duchenne muscular dystrophy T Meier, C Rummey, M Leinonen, P Spagnolo, OH Mayer, GM Buyse, ... Neuromuscular Disorders 27 (4), 307-314, 2017 | 65 | 2017 |
Rating disease progression of Friedreich’s ataxia by the International Cooperative Ataxia Rating Scale: analysis of a 603-patient database G Metz, N Coppard, JM Cooper, MB Delatycki, A Dürr, NA Di Prospero, ... Brain 136 (1), 259-268, 2013 | 62 | 2013 |
The orally active melanocortin-4 receptor antagonist BL-6020/979: a promising candidate for the treatment of cancer cachexia R Dallmann, P Weyermann, C Anklin, M Boroff, K Bray-French, B Cardel, ... Journal of cachexia, sarcopenia and muscle 2, 163-174, 2011 | 62 | 2011 |
Synthesis of Enantiopure Axially Chiral C3-Symmetric Tripodal Ligands and Their Application as Catalysts in the Asymmetric Addition of Dialkylzinc to Aldehydes G Bringmann, RM Pfeifer, C Rummey, K Hartner, M Breuning The Journal of Organic Chemistry 68 (18), 6859-6863, 2003 | 60 | 2003 |
Treatment effect of idebenone on inspiratory function in patients with Duchenne muscular dystrophy GM Buyse, T Voit, U Schara, CSM Straathof, MG D'Angelo, G Bernert, ... Pediatric pulmonology 52 (4), 508-515, 2017 | 53 | 2017 |