| Protein misfolding, functional amyloid, and human disease F Chiti, CM Dobson Annu. Rev. Biochem. 75 (1), 333-366, 2006 | 7501 | 2006 |
| Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases M Bucciantini, E Giannoni, F Chiti, F Baroni, L Formigli, J Zurdo, N Taddei, ... nature 416 (6880), 507-511, 2002 | 3022 | 2002 |
| Protein misfolding, amyloid formation, and human disease: a summary of progress over the last decade F Chiti, CM Dobson Annual review of biochemistry 86 (1), 27-68, 2017 | 2424 | 2017 |
| Designing conditions for in vitro formation of amyloid protofilaments and fibrils F Chiti, P Webster, N Taddei, A Clark, M Stefani, G Ramponi, CM Dobson Proceedings of the National Academy of Sciences 96 (7), 3590-3594, 1999 | 1378 | 1999 |
| Rationalization of the effects of mutations on peptide andprotein aggregation rates F Chiti, M Stefani, N Taddei, G Ramponi, CM Dobson Nature 424 (6950), 805-808, 2003 | 1276 | 2003 |
| Amyloid formation by globular proteins under native conditions F Chiti, CM Dobson Nature chemical biology 5 (1), 15-22, 2009 | 960 | 2009 |
| Prediction of “aggregation-prone” and “aggregation-susceptible” regions in proteins associated with neurodegenerative diseases AP Pawar, KF Dubay, J Zurdo, F Chiti, M Vendruscolo, CM Dobson Journal of molecular biology 350 (2), 379-392, 2005 | 716 | 2005 |
| A causative link between the structure of aberrant protein oligomers and their toxicity S Campioni, B Mannini, M Zampagni, A Pensalfini, C Parrini, ... Nature chemical biology 6 (2), 140-147, 2010 | 629 | 2010 |
| Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers G Fusco, SW Chen, PTF Williamson, R Cascella, M Perni, JA Jarvis, ... Science 358 (6369), 1440-1443, 2017 | 610 | 2017 |
| Kinetic partitioning of protein folding and aggregation F Chiti, N Taddei, F Baroni, C Capanni, M Stefani, G Ramponi, ... nature structural biology 9 (2), 137-143, 2002 | 513 | 2002 |
| Prediction of aggregation-prone regions in structured proteins GG Tartaglia, AP Pawar, S Campioni, CM Dobson, F Chiti, M Vendruscolo Journal of molecular biology 380 (2), 425-436, 2008 | 505 | 2008 |
| Prefibrillar amyloid protein aggregates share common features of cytotoxicity M Bucciantini, G Calloni, F Chiti, L Formigli, D Nosi, CM Dobson, ... Journal of Biological Chemistry 279 (30), 31374-31382, 2004 | 469 | 2004 |
| Prediction of the absolute aggregation rates of amyloidogenic polypeptide chains KF DuBay, AP Pawar, F Chiti, J Zurdo, CM Dobson, M Vendruscolo Journal of molecular biology 341 (5), 1317-1326, 2004 | 385 | 2004 |
| Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases F Chiti, M Calamai, N Taddei, M Stefani, G Ramponi, CM Dobson Proceedings of the National Academy of Sciences 99 (suppl_4), 16419-16426, 2002 | 354 | 2002 |
| Mutational analysis of acylphosphatase suggests the importance of topology and contact order in protein folding F Chiti, N Taddei, PM White, M Bucciantini, F Magherini, M Stefani, ... Nature structural biology 6 (11), 1005-1009, 1999 | 346 | 1999 |
| Protein misfolded oligomers: experimental approaches, mechanism of formation, and structure-toxicity relationships F Bemporad, F Chiti Chemistry & biology 19 (3), 315-327, 2012 | 320 | 2012 |
| A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Müller, PK Challa, ... Proceedings of the National Academy of Sciences 114 (6), E1009-E1017, 2017 | 307 | 2017 |
| Prefibrillar amyloid aggregates could be generic toxins in higher organisms S Baglioni, F Casamenti, M Bucciantini, LM Luheshi, N Taddei, F Chiti, ... Journal of Neuroscience 26 (31), 8160-8167, 2006 | 304 | 2006 |
| Mutational analysis of the propensity for amyloid formation by a globular protein F Chiti, N Taddei, M Bucciantini, P White, G Ramponi, CM Dobson The EMBO journal, 2000 | 296 | 2000 |
| Short amino acid stretches can mediate amyloid formation in globular proteins: the Src homology 3 (SH3) case S Ventura, J Zurdo, S Narayanan, M Parreño, R Mangues, B Reif, F Chiti, ... Proceedings of the National Academy of Sciences 101 (19), 7258-7263, 2004 | 290 | 2004 |
