Weak interactions govern the viscosity of concentrated antibody solutions: high-throughput analysis using the diffusion interaction parameter BD Connolly, C Petry, S Yadav, B Demeule, N Ciaccio, JMR Moore, ... Biophysical journal 103 (1), 69-78, 2012 | 346 | 2012 |
The influence of charge distribution on self-association and viscosity behavior of monoclonal antibody solutions S Yadav, TM Laue, DS Kalonia, SN Singh, SJ Shire Molecular pharmaceutics 9 (4), 791-802, 2012 | 294 | 2012 |
Specific interactions in high concentration antibody solutions resulting in high viscosity S Yadav, JUN Liu, SJ Shire, DS Kalonia Journal of pharmaceutical sciences 99 (3), 1152-1168, 2010 | 281 | 2010 |
Factors affecting the viscosity in high concentration solutions of different monoclonal antibodies S Yadav, SJ Shire, DS Kalonia Journal of pharmaceutical sciences 99 (12), 4812-4829, 2010 | 249 | 2010 |
Viscosity behavior of high-concentration monoclonal antibody solutions: correlation with interaction parameter and electroviscous effects S Yadav, SJ Shire, DS Kalonia Journal of pharmaceutical sciences 101 (3), 998-1011, 2012 | 180 | 2012 |
Viscosity analysis of high concentration bovine serum albumin aqueous solutions S Yadav, SJ Shire, DS Kalonia Pharmaceutical research 28, 1973-1983, 2011 | 153 | 2011 |
Establishing a link between amino acid sequences and self-associating and viscoelastic behavior of two closely related monoclonal antibodies S Yadav, A Sreedhara, S Kanai, J Liu, S Lien, H Lowman, DS Kalonia, ... Pharmaceutical research 28, 1750-1764, 2011 | 153 | 2011 |
Monoclonal antibody self-association, cluster formation, and rheology at high concentrations WG Lilyestrom, S Yadav, SJ Shire, TM Scherer The Journal of Physical Chemistry B 117 (21), 6373-6384, 2013 | 145 | 2013 |
Polysorbate 20 degradation in biopharmaceutical formulations: quantification of free fatty acids, characterization of particulates, and insights into the degradation mechanism A Tomlinson, B Demeule, B Lin, S Yadav Molecular pharmaceutics 12 (11), 3805-3815, 2015 | 140 | 2015 |
The role of amino acid sequence in the self-association of therapeutic monoclonal antibodies: insights from coarse-grained modeling A Chaudhri, IE Zarraga, S Yadav, TW Patapoff, SJ Shire, GA Voth The journal of physical chemistry B 117 (5), 1269-1279, 2013 | 123 | 2013 |
Comparison of binding characteristics and in vitro activities of three inhibitors of vascular endothelial growth factor A J Yang, X Wang, G Fuh, L Yu, E Wakshull, M Khosraviani, ES Day, ... Molecular pharmaceutics 11 (10), 3421-3430, 2014 | 103 | 2014 |
Considerations for the use of polysorbates in biopharmaceuticals MT Jones, HC Mahler, S Yadav, D Bindra, V Corvari, RM Fesinmeyer, ... Pharmaceutical Research 35, 1-8, 2018 | 99 | 2018 |
Understanding particle formation: solubility of free fatty acids as polysorbate 20 degradation byproducts in therapeutic monoclonal antibody formulations N Doshi, B Demeule, S Yadav Molecular pharmaceutics 12 (11), 3792-3804, 2015 | 99 | 2015 |
Use of dynamic light scattering to determine second virial coefficient in a semidilute concentration regime S Yadav, TM Scherer, SJ Shire, DS Kalonia Analytical biochemistry 411 (2), 292-296, 2011 | 88 | 2011 |
Solubility challenges in high concentration monoclonal antibody formulations: relationship with amino acid sequence and intermolecular interactions M Pindrus, SJ Shire, RF Kelley, B Demeule, R Wong, Y Xu, S Yadav Molecular pharmaceutics 12 (11), 3896-3907, 2015 | 72 | 2015 |
Compatibility and stability of pertuzumab and trastuzumab admixtures in iv infusion bags for coadministration ZWK Glover, L Gennaro, S Yadav, B Demeule, PY Wong, A Sreedhara Journal of pharmaceutical sciences 102 (3), 794-812, 2013 | 68 | 2013 |
Dipole-dipole interaction in antibody solutions: correlation with viscosity behavior at high concentration SN Singh, S Yadav, SJ Shire, DS Kalonia Pharmaceutical research 31, 2549-2558, 2014 | 66 | 2014 |
Comparative study of analytical techniques for determining protein charge DI Filoti, SJ Shire, S Yadav, TM Laue Journal of pharmaceutical sciences 104 (7), 2123-2131, 2015 | 59 | 2015 |
Degradation Mechanisms of Polysorbate 20 Differentiated by 18O-labeling and Mass Spectrometry L Zhang, S Yadav, B Demeule, YJ Wang, O Mozziconacci, C Schӧneich Pharmaceutical research 34, 84-100, 2017 | 55 | 2017 |
Evaluation of super refined™ polysorbate 20 with respect to polysorbate degradation, particle formation and protein stability N Doshi, R Fish, K Padilla, S Yadav Journal of pharmaceutical sciences 109 (10), 2986-2995, 2020 | 31 | 2020 |