KHNYN is essential for the zinc finger antiviral protein (ZAP) to restrict HIV-1 containing clustered CpG dinucleotides M Ficarelli, H Wilson, R Pedro Galão, M Mazzon, I Antzin-Anduetza, ... Elife 8, e46767, 2019 | 121 | 2019 |
CpG dinucleotides inhibit HIV-1 replication through zinc finger antiviral protein (ZAP)-dependent and-independent mechanisms M Ficarelli, I Antzin-Anduetza, R Hugh-White, AE Firth, H Sertkaya, ... Journal of Virology 94 (6), 10.1128/jvi. 01337-19, 2020 | 71 | 2020 |
Targeted restriction of viral gene expression and replication by the ZAP antiviral system M Ficarelli, SJD Neil, CM Swanson Annual Review of Virology 8 (1), 265-283, 2021 | 58 | 2021 |
Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation MJ Lista, PM Matos, TJA Maguire, K Poulton, E Ortiz-Zapater, R Page, ... PLoS One 16 (9), e0256813, 2021 | 37 | 2021 |
S-farnesylation is essential for antiviral activity of the long ZAP isoform against RNA viruses with diverse replication strategies D Kmiec, MJ Lista, M Ficarelli, CM Swanson, SJD Neil PLoS Pathogens 17 (10), e1009726, 2021 | 31 | 2021 |
Homebrew: An economical and sensitive glassmilk-based nucleic-acid extraction method for SARS-CoV-2 diagnostics R Page, E Scourfield, M Ficarelli, SW McKellar, KL Lee, TJA Maguire, ... Cell Reports Methods 2 (3), 100186, 2022 | 8* | 2022 |
HIV-1 sequences in lentiviral vector genomes can be substantially reduced without compromising transduction efficiency H Sertkaya, M Ficarelli, NP Sweeney, H Parker, CA Vink, CM Swanson Scientific Reports 11 (1), 12067, 2021 | 8 | 2021 |
A nuclear export signal in KHNYN required for its antiviral activity evolved as ZAP emerged in tetrapods MJ Lista, M Ficarelli, H Wilson, D Kmiec, RL Youle, J Wanford, ... Journal of Virology, e00872-22, 2023 | 2 | 2023 |
Minimal impact of ZAP on lentiviral vector production and transduction efficiency H Sertkaya, L Hidalgo, M Ficarelli, D Kmiec, AW Signell, S Ali, H Parker, ... Molecular Therapy-Methods & Clinical Development 23, 147-157, 2021 | 1 | 2021 |
Regulation of HIV-1 replication by CpG dinucleotides, ZAP and KHNYN M Ficarelli King's College London, 2022 | | 2022 |
Regulation of KHNYN antiviral activity by the extended di-KH domain and nucleo-cytoplasmic trafficking MJ Lista, RP Galão, M Ficarelli, D Kmiec, H Wilson, H Winstone, ... bioRxiv, 2021.12. 22.473955, 2021 | | 2021 |