关注
Mary Kay H Pflum
Mary Kay H Pflum
在 wayne.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Isoform-selective histone deacetylase inhibitors
AV Bieliauskas, MKH Pflum
Chemical Society Reviews 37 (7), 1402-1413, 2008
4152008
Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation
MKH Pflum, JK Tong, WS Lane, SL Schreiber
Journal of Biological Chemistry 276 (50), 47733-47741, 2001
3452001
Mechanism of DNA-binding enhancement by the human T-cell leukaemia virus transactivator Tax
AM Baranger, CR Palmer, MK Hamm, HA Giebler, A Brauweiler, ...
Nature 376 (6541), 606-608, 1995
2051995
Kinase-catalyzed biotinylation for phosphoprotein detection
KD Green, MKH Pflum
Journal of the American Chemical Society 129 (1), 10-11, 2007
1262007
Phosphorylation-dependent kinase–substrate cross-linking
S Suwal, MKH Pflum
Angewandte Chemie (International ed. in English) 49 (9), 1627, 2010
822010
Structural requirements of HDAC inhibitors: SAHA analogs functionalized adjacent to the hydroxamic acid
AV Bieliauskas, SVW Weerasinghe, MKH Pflum
Bioorganic & medicinal chemistry letters 17 (8), 2216-2219, 2007
732007
Residues in the 11 Å channel of histone deacetylase 1 promote catalytic activity: implications for designing isoform-selective histone deacetylase inhibitors
SVW Weerasinghe, G Estiu, O Wiest, MKH Pflum
Journal of medicinal chemistry 51 (18), 5542-5551, 2008
702008
Mutagenesis studies of the 14 Å internal cavity of histone deacetylase 1: insights toward the acetate-escape hypothesis and selective inhibitor design
MK Wambua, DA Nalawansha, AT Negmeldin, MKH Pflum
Journal of medicinal chemistry 57 (3), 642-650, 2014
592014
Exploring kinase cosubstrate promiscuity: monitoring kinase activity through dansylation
KD Green, MKH Pflum
Chembiochem: a European journal of chemical biology 10 (2), 234, 2009
572009
LSD1 substrate binding and gene expression are affected by HDAC1-mediated deacetylation
DA Nalawansha, MKH Pflum
ACS chemical biology 12 (1), 254-264, 2017
552017
The structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity
AT Negmeldin, JR Knoff, MKH Pflum
European journal of medicinal chemistry 143, 1790-1806, 2018
512018
Structural requirements of HDAC inhibitors: SAHA analogues modified at the C2 position display HDAC6/8 selectivity
AT Negmeldin, G Padige, AV Bieliauskas, MKH Pflum
ACS Medicinal Chemistry Letters 8 (3), 281-286, 2017
482017
HDAC inhibitor-induced mitotic arrest is mediated by Eg5/KIF11 acetylation
DA Nalawansha, ID Gomes, MK Wambua, MKH Pflum
Cell chemical biology 24 (4), 481-492. e5, 2017
432017
A cell‐permeable ATP analogue for kinase‐catalyzed biotinylation
AE Fouda, MKH Pflum
Angewandte Chemie International Edition 54 (33), 9618-9621, 2015
432015
The structural requirements of histone deacetylase inhibitors: Suberoylanilide hydroxamic acid analogs modified at the C3 position display isoform selectivity
SE Choi, SVW Weerasinghe, MKH Pflum
Bioorganic & medicinal chemistry letters 21 (20), 6139-6142, 2011
422011
Phosphopeptide Modification and Enrichment by Oxidation–Reduction Condensation
M Warthaka, P Karwowska-Desaulniers, MKH Pflum
ACS chemical biology 1 (11), 697-701, 2006
392006
The structural requirements of histone deacetylase inhibitors: Suberoylanilide hydroxamic acid analogs modified at the C6 position
SE Choi, MKH Pflum
Bioorganic & medicinal chemistry letters 22 (23), 7084-7086, 2012
372012
Largazole analogues embodying radical changes in the depsipeptide ring: Development of a more selective and highly potent analogue
J Almaliti, AA Al-Hamashi, AT Negmeldin, CL Hanigan, L Perera, ...
Journal of medicinal chemistry 59 (23), 10642-10660, 2016
342016
K-CLASP: a tool to identify phosphosite specific kinases and interacting proteins
PM Dedigama-Arachchige, MKH Pflum
ACS chemical biology 11 (12), 3251-3255, 2016
322016
The generality of kinase-catalyzed biotinylation
C Senevirathne, DM Embogama, TA Anthony, AE Fouda, MKH Pflum
Bioorganic & medicinal chemistry 24 (1), 12-19, 2016
322016
系统目前无法执行此操作,请稍后再试。
文章 1–20