| Strategies for delivering therapeutics across the blood–brain barrier GC Terstappen, AH Meyer, RD Bell, W Zhang Nature Reviews Drug Discovery 20 (5), 362-383, 2021 | 525 | 2021 |
| Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma. H Tsuda, WD Zhang, Y Shimosato, J Yokota, M Terada, T Sugimura, ... Proceedings of the National Academy of Sciences 87 (17), 6791-6794, 1990 | 376 | 1990 |
| Cholesterol retention in Alzheimer's brain is responsible for high β-and γ-secretase activities and Aβ production H Xiong, D Callaghan, A Jones, DG Walker, LF Lue, TG Beach, LI Sue, ... Neurobiology of disease 29 (3), 422-437, 2008 | 306 | 2008 |
| Expression and functional characterization of ABCG2 in brain endothelial cells and vessels W Zhang, J Mojsilovic-Petrovic, MF Andrade, H Zhang, M Ball, ... The FASEB Journal 17 (14), 1-24, 2003 | 268 | 2003 |
| Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway V Vukic, D Callaghan, D Walker, LF Lue, QY Liu, PO Couraud, IA Romero, ... Neurobiology of disease 34 (1), 95-106, 2009 | 257 | 2009 |
| Detection and identification of human influenza viruses by the polymerase chain reaction W Zhang, D Evans Journal of Virological Methods 33 (1-2), 165-189, 1991 | 254 | 1991 |
| ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood–brain barrier for Aβ1–40 peptides H Xiong, D Callaghan, A Jones, J Bai, I Rasquinha, C Smith, K Pei, ... Journal of Neuroscience 29 (17), 5463-5475, 2009 | 246 | 2009 |
| Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes J Mojsilovic-Petrovic, D Callaghan, H Cui, C Dean, DB Stanimirovic, ... Journal of neuroinflammation 4, 1-15, 2007 | 235 | 2007 |
| Increased expression of bioactive chemokines in human cerebromicrovascular endothelial cells and astrocytes subjected to simulated ischemia in vitro W Zhang, C Smith, A Shapiro, R Monette, J Hutchison, D Stanimirovic Journal of neuroimmunology 101 (2), 148-160, 1999 | 169 | 1999 |
| Inflammatory Activation of Human Brain Endothelial Cells by Hypoxic Astrocytes In Vitro is Mediated by IL-1β W Zhang, C Smith, C Howlett, D Stanimirovic Journal of Cerebral Blood Flow & Metabolism 20 (6), 967-978, 2000 | 158 | 2000 |
| Evidence that hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of interleukin-1β (IL-1β) in astrocyte cultures W Zhang, JM Petrovic, D Callaghan, A Jones, H Cui, C Howlett, ... Journal of neuroimmunology 174 (1-2), 63-73, 2006 | 155 | 2006 |
| Characterization of ABCB9, an ATP binding cassette protein associated with lysosomes F Zhang, W Zhang, L Liu, CL Fisher, D Hui, S Childs, K Dorovini-Zis, ... Journal of Biological Chemistry 275 (30), 23287-23294, 2000 | 145 | 2000 |
| Frequent loss of heterozygosity on chromosomes 16 and 4 in human hepatocellular carcinoma W Zhang, S Hirohashi, H Tsuda, Y Shimosato, J Yokota, M Terada, ... Japanese journal of cancer research 81 (2), 108-111, 1990 | 145 | 1990 |
| ABC transporters and drug efflux at the blood-brain barrier S Shen, W Zhang Reviews in the Neurosciences 21 (1), 29-54, 2010 | 136 | 2010 |
| ABCG2 reduces ROS‐mediated toxicity and inflammation: a potential role in Alzheimer’s disease S Shen, D Callaghan, C Juzwik, H Xiong, P Huang, W Zhang Journal of neurochemistry 114 (6), 1590-1604, 2010 | 126 | 2010 |
| Apolipoprotein E, amyloid-beta, and neuroinflammation in Alzheimer’s disease E Dorey, N Chang, QY Liu, Z Yang, W Zhang Neuroscience bulletin 30, 317-330, 2014 | 123 | 2014 |
| Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human W Zhang, QY Liu, AS Haqqani, S Leclerc, Z Liu, F Fauteux, E Baumann, ... Fluids and Barriers of the CNS 17, 1-17, 2020 | 120 | 2020 |
| Biochemical and behavioral characterization of the double transgenic mouse model (APPswe/PS1dE9) of Alzheimer’s disease H Xiong, D Callaghan, J Wodzinska, J Xu, M Premyslova, QY Liu, ... Neuroscience bulletin 27 (4), 2011 | 110 | 2011 |
| Development of rapid staining protocols for laser-capture microdissection of brain vessels from human and rat coupled to gene expression analyses J Mojsilovic-Petrovic, M Nesic, A Pen, W Zhang, D Stanimirovic Journal of neuroscience methods 133 (1-2), 39-48, 2004 | 86 | 2004 |
| Association between APOC1 Polymorphism and Alzheimer’s Disease: A Case-Control Study and Meta-Analysis Q Zhou, F Zhao, Z Lv, C Zheng, W Zheng, L Sun, N Wang, S Pang, ... PloS one 9 (1), e87017, 2014 | 74 | 2014 |
