Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity D Boucher, M Monteleone, RC Coll, KW Chen, CM Ross, JL Teo, ... Journal of Experimental Medicine 215 (3), 827-840, 2018 | 489 | 2018 |
Inflammatory Caspases: Toward a Unified Model for Caspase Activation by Inflammasomes C Ross, AH Chan, JB von Pein, MP Maddugoda, D Boucher, K Schroder Annual review of immunology 40, 249-269, 2022 | 83 | 2022 |
Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome C Ross, AH Chan, J Von Pein, D Boucher, K Schroder Life science alliance 1 (6), 2018 | 67 | 2018 |
Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP) G Foley, A Mora, CM Ross, S Bottoms, L Sützl, ML Lamprecht, J Zaugg, ... PLoS computational biology 18 (10), e1010633, 2022 | 25 | 2022 |
Identifying and engineering ancient variants of enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP) G Foley, A Mora, CM Ross, S Bottoms, L Sützl, ML Lamprecht, J Zaugg, ... BioRxiv, 2019.12. 30.891457, 2020 | 15 | 2020 |
Using the evolutionary history of proteins to engineer insertion-deletion mutants from robust, ancestral templates using graphical representation of ancestral sequence … CM Ross, G Foley, M Boden, EMJ Gillam Enzyme engineering: methods and protocols, 85-110, 2022 | 13 | 2022 |
Quantifying caspase-1 activity in murine macrophages D Boucher, A Chan, C Ross, K Schroder Inflammation and Cancer: Methods and Protocols, 163-176, 2018 | 10 | 2018 |
NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome JR Coombs, A Zamoshnikova, CL Holley, MP Maddugoda, DET Teo, ... Science Signaling 17 (820), eabg8145, 2024 | 4 | 2024 |
Engineering Biocatalysts for the C‐H Activation of Fatty Acids by Ancestral Sequence Reconstruction BS Jones, CM Ross, G Foley, N Pozhydaieva, JW Sharratt, N Kress, ... Angewandte Chemie International Edition, e202314869, 2024 | 2 | 2024 |
Engineering Biocatalysts for the CH Activation of Fatty Acids using Ancestral Sequence Reconstruction BS Jones, CM Ross, G Foley, N Kress, RES Thomson, Y Gumulya, ... | | 2023 |
Ancestral reconstruction and characterisation of the CYP2U subfamily CM Petroeschevsky | | 2022 |