Genetic variants associated with phenytoin-related severe cutaneous adverse reactions WH Chung, WC Chang, YS Lee, YY Wu, CH Yang, HC Ho, MJ Chen, ... Jama 312 (5), 525-534, 2014 | 321 | 2014 |
Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: the impact of renal insufficiency, high plasma levels of oxypurinol and granulysin WH Chung, WC Chang, SL Stocker, CG Juo, GG Graham, MHH Lee, ... Annals of the rheumatic diseases 74 (12), 2157-2164, 2015 | 227 | 2015 |
Risk and association of HLA with oxcarbazepine-induced cutaneous adverse reactions in Asians CB Chen, YH Hsiao, T Wu, MS Hsih, W Tassaneeyakul, TP Jorns, ... Neurology 88 (1), 78-86, 2017 | 133 | 2017 |
Genotype–phenotype association between HLA and carbamazepine-induced hypersensitivity reactions: strength and clinical correlations YH Hsiao, RCY Hui, T Wu, WC Chang, MS Hsih, CH Yang, HC Ho, ... Journal of dermatological science 73 (2), 101-109, 2014 | 116 | 2014 |
Impact of the HLA-B* 58: 01 allele and renal impairment on allopurinol-induced cutaneous adverse reactions CY Ng, YT Yeh, CW Wang, SI Hung, CH Yang, YC Chang, WC Chang, ... Journal of Investigative Dermatology 136 (7), 1373-1381, 2016 | 104 | 2016 |
HLA Alleles and CYP2C9*3 as Predictors of Phenytoin Hypersensitivity in East Asians SC Su, CB Chen, WC Chang, CW Wang, WL Fan, LY Lu, R Nakamura, ... Clinical Pharmacology & Therapeutics 105 (2), 476-485, 2019 | 70 | 2019 |
SJS/TEN 2019: from science to translation WC Chang, R Abe, P Anderson, W Anderson, MR Ardern-Jones, ... Journal of dermatological science 98 (1), 2-12, 2020 | 65 | 2020 |
Genetic variants of PPAR-gamma coactivator 1B augment NLRP3-mediated inflammation in gouty arthritis WC Chang, YJ Jan Wu, WH Chung, YS Lee, SW Chin, TJ Chen, ... Rheumatology 56 (3), 457-466, 2017 | 56 | 2017 |
Rhein, an anthraquinone drug, suppresses the NLRP3 inflammasome and macrophage activation in urate crystal-induced gouty inflammation WC Chang, MT Chu, CY Hsu, YJJ Wu, JY Lee, TJ Chen, WH Chung, ... The American journal of Chinese medicine 47 (01), 135-151, 2019 | 50 | 2019 |
Challenges and opportunities in implementing pharmacogenetic testing in clinical settings WC Chang, R Tanoshima, CJD Ross, BC Carleton Annual Review of Pharmacology and Toxicology 61 (1), 65-84, 2021 | 46 | 2021 |
Fas/Fas ligand mediates keratinocyte death in sunitinib-induced hand-foot skin reaction CN Yeh, WH Chung, SC Su, YY Chen, CT Cheng, YL Lin, WC Chang, ... Journal of Investigative Dermatology 134 (11), 2768-2775, 2014 | 30 | 2014 |
Detecting lesional granulysin levels for rapid diagnosis of cytotoxic T lymphocyte–mediated bullous skin disorders CB Chen, KL Kuo, CW Wang, CW Lu, RCY Hui, KL Lu, WC Chang, ... The Journal of Allergy and Clinical Immunology: In Practice 9 (3), 1327-1337. e3, 2021 | 27 | 2021 |
An update on CYP2C9 polymorphisms and phenytoin metabolism: implications for adverse effects WC Chang, SI Hung, BC Carleton, WH Chung Expert Opinion on Drug Metabolism & Toxicology 16 (8), 723-734, 2020 | 21 | 2020 |
Granulysin-based lymphocyte activation test for evaluating drug causality in antiepileptics-induced severe cutaneous adverse reactions MT Chu, CW Wang, WC Chang, CB Chen, WH Chung, SI Hung Journal of Investigative Dermatology 141 (6), 1461-1472. e10, 2021 | 18 | 2021 |
Delayed drug hypersensitivity reactions: molecular recognition, genetic susceptibility, and immune mediators MT Chu, WC Chang, SC Pao, SI Hung Biomedicines 11 (1), 177, 2023 | 15 | 2023 |
Updates in SJS/TEN: collaboration, innovation, and community ME Marks, RK Botta, R Abe, TM Beachkofsky, I Boothman, BC Carleton, ... Frontiers in Medicine 10, 1213889, 2023 | 9 | 2023 |
Genetic Association and Expression Correlation between Colony‐Stimulating Factor 1 Gene Encoding M‐CSF and Adult‐Onset Still’s Disease YM Chen, WT Hung, WC Chang, CW Hsieh, WH Chung, JL Lan, ... Journal of Immunology Research 2020 (1), 8640719, 2020 | 8 | 2020 |
DNA methylation of ITGB2 contributes to allopurinol hypersensitivity Y Liu, CW Wang, CB Chen, KH Yu, YJ Wu, SE Choon, WC Chang, F Yang, ... Clinical Immunology 248, 109250, 2023 | 5 | 2023 |
Patient‐specific genetic factors predict treatment failure in sofosbuvir‐treated patients with chronic hepatitis C CM Loucks, JJ Lin, JN Trueman, BI Drögemöller, GEB Wright, WC Chang, ... Liver International 42 (4), 796-808, 2022 | 5 | 2022 |
Attenuation of Wnt/β-catenin signaling in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis CB Chen, WC Chang, MY Wu, TY Kao, YW Wang, CW Wang, CJ Chen, ... International journal of biological sciences 16 (2), 353, 2020 | 3 | 2020 |