Immunoglobulin light chain amyloid aggregation LM Blancas-Mejia, P Misra, CJ Dick, SA Cooper, KR Redhage, ... Chemical communications 54 (76), 10664-10674, 2018 | 85 | 2018 |
Cell damage in light chain amyloidosis: fibril internalization, toxicity and cell-mediated seeding M Marin-Argany, Y Lin, P Misra, A Williams, JS Wall, KG Howell, ... Journal of Biological Chemistry 291 (38), 19813-19825, 2016 | 72 | 2016 |
Alpha‐synuclein oligomers and neurofilament light chain predict phenoconversion of pure autonomic failure W Singer, AM Schmeichel, M Shahnawaz, JD Schmelzer, DM Sletten, ... Annals of neurology 89 (6), 1212-1220, 2021 | 62 | 2021 |
Rapid α-oligomer formation mediated by the Aβ C terminus initiates an amyloid assembly pathway P Misra, R Kodali, S Chemuru, K Kar, R Wetzel Nature Communications 7 (12419), 2016 | 57 | 2016 |
An aggregate weight-normalized thioflavin-t measurement scale for characterizing polymorphic amyloids and assembly intermediates R Wetzel, S Chemuru, P Misra, R Kodali, S Mukherjee, K Kar Peptide Self-Assembly: Methods and Protocols, 121-144, 2018 | 29 | 2018 |
Mechanistic insights into the early events in the aggregation of immunoglobulin light chains P Misra, LM Blancas-Mejia, M Ramirez-Alvarado Biochemistry 58 (29), 3155-3168, 2019 | 26 | 2019 |
Differences in protein concentration dependence for nucleation and elongation in light chain amyloid formation LM Blancas-Mejía, P Misra, M Ramirez-Alvarado Biochemistry 56 (5), 757-766, 2017 | 26 | 2017 |
Volumetric and calorimetric investigations of molecular interactions in some amino acids and peptides in the combined presence of surfactants and glycine betaine PP Misra, N Kishore The Journal of Chemical Thermodynamics 54, 453-463, 2012 | 26 | 2012 |
Light chain amyloidosis induced inflammatory changes in cardiomyocytes and adipose-derived mesenchymal stromal cells TL Jordan, K Maar, KR Redhage, P Misra, LM Blancas-Mejia, CJ Dick, ... Leukemia 34 (5), 1383-1393, 2020 | 25 | 2020 |
Biophysical analysis of partially folded state of α-lactalbumin in the presence of cationic and anionic surfactants PP Misra, N Kishore Journal of colloid and interface science 354 (1), 234-247, 2011 | 24 | 2011 |
Glycine betaine: A widely reported osmolyte induces differential and selective conformational stability and enhances aggregation in some proteins in the presence of surfactants PP Misra, N Kishore Biopolymers 97 (12), 933-949, 2012 | 14 | 2012 |
Differential modulation in binding of ketoprofen to bovine serum albumin in the presence and absence of surfactants: spectroscopic and calorimetric insights PP Misra, N Kishore Chemical Biology & Drug Design 82 (1), 81-98, 2013 | 13 | 2013 |
Assays for light chain amyloidosis formation and cytotoxicity LM Blancas-Mejia, P Misra, CJ Dick, M Marin-Argany, KR Redhage, ... Protein Misfolding Diseases: Methods and Protocols, 123-153, 2019 | 9 | 2019 |
Early events in light chain aggregation at physiological pH reveal new insights on assembly, stability, and aggregate dissociation P Misra, M Ramirez-Alvarado Amyloid 28 (2), 113-124, 2021 | 8 | 2021 |
Pathologic light chain amyloidosis oligomer detection in urinary extracellular vesicles as a diagnostic tool for response and progression of disease SA Cooper, CJ Dick, P Misra, N Leung, CA Schinstock, ... Frontiers in Oncology 12, 978198, 2022 | 2 | 2022 |
Systemic misfolding of immunoglobulins in the test tube and in the cell M Ramirez‐Alvarado, CJ Dick, LM Blancas‐Mejia, P Misra, Y Lin, ... The FASEB Journal 32, 247.3-247.3, 2018 | 2 | 2018 |
Target engagement and immunogenicity of an active immunotherapeutic targeting pathological α-synuclein: a phase 1 placebo-controlled trial P Eijsvogel, P Misra, L Concha-Marambio, JD Boyd, S Ding, L Fedor, ... Nature Medicine, 1-10, 2024 | | 2024 |
Biophysical characterization of human-cell-expressed, full-length κI O18/O8, AL-09, λ6a, and Wil immunoglobulin light chains P Misra, A Tischer, L Lampe, V Pierluissi-Ruiz, CJ Dick, B Bragantini, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1872 (3), 140993, 2024 | | 2024 |