关注
Taiji Oashi
Taiji Oashi
Research Scientist, Kyowa Hakko Kirin Co., Ltd.
在 kyowa-kirin.co.jp 的电子邮件经过验证
标题
引用次数
引用次数
年份
A Graves’ Disease-Associated Kozak Sequence Single-Nucleotide Polymorphism Enhances the Efficiency of CD40 Gene Translation: A Case for Translational …
EM Jacobson, E Concepcion, T Oashi, Y Tomer
Endocrinology 146 (6), 2684-2691, 2005
2682005
Arginine at position 74 of the HLA-DR β1 chain is associated with Graves' disease
Y Ban, TF Davies, DA Greenberg, ES Concepcion, R Osman, T Oashi, ...
Genes & immunity 5 (3), 203-208, 2004
1832004
Molecular amino acid signatures in the MHC class II peptide-binding pocket predispose to autoimmune thyroiditis in humans and in mice
F Menconi, MC Monti, DA Greenberg, T Oashi, R Osman, TF Davies, ...
Proceedings of the National Academy of Sciences 105 (37), 14034-14039, 2008
1352008
Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail
K Yamoah, T Oashi, A Sarikas, S Gazdoiu, R Osman, ZQ Pan
Proceedings of the National Academy of Sciences 105 (34), 12230-12235, 2008
1142008
The small molecule IMR-1 inhibits the notch transcriptional activation complex to suppress tumorigenesis
L Astudillo, TG Da Silva, Z Wang, X Han, K Jin, J VanWye, X Zhu, ...
Cancer research 76 (12), 3593-3603, 2016
762016
Turning defense into offense: defensin mimetics as novel antibiotics targeting lipid II
KM Varney, AMJJ Bonvin, M Pazgier, J Malin, W Yu, E Ateh, T Oashi, ...
PLoS pathogens 9 (11), e1003732, 2013
722013
Small-molecule inhibitors of ERK-mediated immediate early gene expression and proliferation of melanoma cells expressing mutated BRaf
R Samadani, J Zhang, A Brophy, T Oashi, UD Priyakumar, EP Raman, ...
The Biochemical Journal 467 (3), 425, 2015
442015
Automated selection of compounds with physicochemical properties to maximize bioavailability and druglikeness
T Oashi, AL Ringer, EP Raman, AD MacKerell Jr
Journal of chemical information and modeling 51 (1), 148-158, 2011
422011
Importance of domain closure for the autoactivation of ERK2
D Barr, T Oashi, K Burkhard, S Lucius, R Samadani, J Zhang, P Shapiro, ...
Biochemistry 50 (37), 8038-8048, 2011
312011
Electrostatic interactions mediate binding of obscurin to small ankyrin 1: biochemical and molecular modeling studies
B Busby, T Oashi, CD Willis, MA Ackermann, ...
Journal of molecular biology 408 (2), 321-334, 2011
222011
siRNA potency enhancement via chemical modifications of nucleotide bases at the 5′-end of the siRNA guide strand
F Shinohara, T Oashi, T Harumoto, T Nishikawa, Y Takayama, H Miyagi, ...
RNA 27 (2), 163-173, 2021
122021
Hydrophobic residues in small ankyrin 1 participate in binding to obscurin
CD Willis, T Oashi, B Busby, AD Mackerell Jr, RJ Bloch
Molecular Membrane Biology 29 (2), 36-51, 2012
122012
Prospects of modulating protein–protein interactions
S Zhong, T Oashi, W Yu, P Shapiro, AD MacKerell Jr
Protein‐Ligand Interactions, 295-329, 2012
52012
Oligonucleotide
F Shinohara, A Makino, J Yamamoto, T Oashi, M Suzuki, J Saito
US Patent App. 13/972,128, 2014
22014
Oligonucleotide
F Shinohara, A Makino, J Yamamoto, T Oashi, M Suzuki, J Saito, ...
US Patent 10,378,011, 2019
12019
Oligonucleotide having non-natural nucleotide at 5′-terminal thereof
F Shinohara, A Makino, J Yamamoto, T Nakajima, T Oashi, M Suzuki, ...
US Patent 10,342,819, 2019
2019
A docking domain directed inhibitor targeting ERK regulated F-site substrates.
J Zhang, T Oashi, R Samadani, K Nevels, K Burkhard, D Priyakumar, ...
Cancer Research 73 (8_Supplement), 4554-4554, 2013
2013
Identification of ERK2-Substrate Protein Inhibitors via Virtual Screening, Biological Assays and X-Ray Crystallography
T Oashi, J Zhang, K Burkhard, UD Priyakumar, E Pozharskiy, P Shapiro, ...
Biophysical Journal 100 (3), 214a, 2011
2011
Interaction of Obscurin a with Small Ankyrin 1
RJ Bloch, B Busby, T Oashi, C Willis, M Ackermann, ...
Biophysical Journal 100 (3), 588a, 2011
2011
Surface-Exposed Hydrophobic Residues on Small Ankyrin-1 Mediate Binding to Obscurin
CD Willis, B Busby, T Oashi, AD MacKerell, RJ Bloch
Biophysical Journal 98 (3), 39a, 2010
2010
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