A Graves’ Disease-Associated Kozak Sequence Single-Nucleotide Polymorphism Enhances the Efficiency of CD40 Gene Translation: A Case for Translational … EM Jacobson, E Concepcion, T Oashi, Y Tomer Endocrinology 146 (6), 2684-2691, 2005 | 268 | 2005 |
Arginine at position 74 of the HLA-DR β1 chain is associated with Graves' disease Y Ban, TF Davies, DA Greenberg, ES Concepcion, R Osman, T Oashi, ... Genes & immunity 5 (3), 203-208, 2004 | 183 | 2004 |
Molecular amino acid signatures in the MHC class II peptide-binding pocket predispose to autoimmune thyroiditis in humans and in mice F Menconi, MC Monti, DA Greenberg, T Oashi, R Osman, TF Davies, ... Proceedings of the National Academy of Sciences 105 (37), 14034-14039, 2008 | 135 | 2008 |
Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail K Yamoah, T Oashi, A Sarikas, S Gazdoiu, R Osman, ZQ Pan Proceedings of the National Academy of Sciences 105 (34), 12230-12235, 2008 | 114 | 2008 |
The small molecule IMR-1 inhibits the notch transcriptional activation complex to suppress tumorigenesis L Astudillo, TG Da Silva, Z Wang, X Han, K Jin, J VanWye, X Zhu, ... Cancer research 76 (12), 3593-3603, 2016 | 76 | 2016 |
Turning defense into offense: defensin mimetics as novel antibiotics targeting lipid II KM Varney, AMJJ Bonvin, M Pazgier, J Malin, W Yu, E Ateh, T Oashi, ... PLoS pathogens 9 (11), e1003732, 2013 | 72 | 2013 |
Small-molecule inhibitors of ERK-mediated immediate early gene expression and proliferation of melanoma cells expressing mutated BRaf R Samadani, J Zhang, A Brophy, T Oashi, UD Priyakumar, EP Raman, ... The Biochemical Journal 467 (3), 425, 2015 | 44 | 2015 |
Automated selection of compounds with physicochemical properties to maximize bioavailability and druglikeness T Oashi, AL Ringer, EP Raman, AD MacKerell Jr Journal of chemical information and modeling 51 (1), 148-158, 2011 | 42 | 2011 |
Importance of domain closure for the autoactivation of ERK2 D Barr, T Oashi, K Burkhard, S Lucius, R Samadani, J Zhang, P Shapiro, ... Biochemistry 50 (37), 8038-8048, 2011 | 31 | 2011 |
Electrostatic interactions mediate binding of obscurin to small ankyrin 1: biochemical and molecular modeling studies B Busby, T Oashi, CD Willis, MA Ackermann, ... Journal of molecular biology 408 (2), 321-334, 2011 | 22 | 2011 |
siRNA potency enhancement via chemical modifications of nucleotide bases at the 5′-end of the siRNA guide strand F Shinohara, T Oashi, T Harumoto, T Nishikawa, Y Takayama, H Miyagi, ... RNA 27 (2), 163-173, 2021 | 12 | 2021 |
Hydrophobic residues in small ankyrin 1 participate in binding to obscurin CD Willis, T Oashi, B Busby, AD Mackerell Jr, RJ Bloch Molecular Membrane Biology 29 (2), 36-51, 2012 | 12 | 2012 |
Prospects of modulating protein–protein interactions S Zhong, T Oashi, W Yu, P Shapiro, AD MacKerell Jr Protein‐Ligand Interactions, 295-329, 2012 | 5 | 2012 |
Oligonucleotide F Shinohara, A Makino, J Yamamoto, T Oashi, M Suzuki, J Saito US Patent App. 13/972,128, 2014 | 2 | 2014 |
Oligonucleotide F Shinohara, A Makino, J Yamamoto, T Oashi, M Suzuki, J Saito, ... US Patent 10,378,011, 2019 | 1 | 2019 |
Oligonucleotide having non-natural nucleotide at 5′-terminal thereof F Shinohara, A Makino, J Yamamoto, T Nakajima, T Oashi, M Suzuki, ... US Patent 10,342,819, 2019 | | 2019 |
A docking domain directed inhibitor targeting ERK regulated F-site substrates. J Zhang, T Oashi, R Samadani, K Nevels, K Burkhard, D Priyakumar, ... Cancer Research 73 (8_Supplement), 4554-4554, 2013 | | 2013 |
Identification of ERK2-Substrate Protein Inhibitors via Virtual Screening, Biological Assays and X-Ray Crystallography T Oashi, J Zhang, K Burkhard, UD Priyakumar, E Pozharskiy, P Shapiro, ... Biophysical Journal 100 (3), 214a, 2011 | | 2011 |
Interaction of Obscurin a with Small Ankyrin 1 RJ Bloch, B Busby, T Oashi, C Willis, M Ackermann, ... Biophysical Journal 100 (3), 588a, 2011 | | 2011 |
Surface-Exposed Hydrophobic Residues on Small Ankyrin-1 Mediate Binding to Obscurin CD Willis, B Busby, T Oashi, AD MacKerell, RJ Bloch Biophysical Journal 98 (3), 39a, 2010 | | 2010 |