| Design, Synthesis and Evaluation of Novel Phthalimide Derivatives as in Vitro Anti-Microbial, Anti-Oxidant and Anti-Inflammatory Agents P F. Lamie, J N. Phillopes, A O. El-Gendy, L Rarova, J Gruz Molecules 20 (9), 16620-16642, 2015 | 73 | 2015 |
| Novel tetrazole and cyanamide derivatives as inhibitors of cyclooxygenase-2 enzyme: design, synthesis, anti-inflammatory evaluation, ulcerogenic liability and docking study PF Lamie, JN Philoppes, AA Azouz, NM Safwat Journal of enzyme inhibition and medicinal chemistry 32 (1), 805-820, 2017 | 67 | 2017 |
| Azole-hydrazone derivatives: Design, synthesis, in vitro biological evaluation, dual EGFR/HER2 inhibitory activity, cell cycle analysis and molecular docking study as … MB Labib, JN Philoppes, PF Lamie, ER Ahmed Bioorganic chemistry 76, 67-80, 2018 | 66 | 2018 |
| Design and synthesis of new benzoxazole/benzothiazole-phthalimide hybrids as antitumor-apoptotic agents JN Philoppes, PF Lamie Bioorganic chemistry 89, 102978, 2019 | 43 | 2019 |
| Pyrazolo [3, 4-d] pyrimidine-based dual EGFR T790M/HER2 inhibitors: design, synthesis, structure–activity relationship and biological activity as potential antitumor and … PF Lamie, AM El-Kalaawy, NSA Latif, LA Rashed, JN Philoppes European Journal of Medicinal Chemistry 214, 113222, 2021 | 34 | 2021 |
| Optimization of pyrazole-based compounds with 1, 2, 4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase … KRA Abdellatif, EKA Abdelall, HAH Elshemy, JN Philoppes, ... Bioorganic chemistry 114, 105122, 2021 | 31 | 2021 |
| New pyrazolopyrimidine derivatives with anticancer activity: Design, synthesis, PIM-1 inhibition, molecular docking study and molecular dynamics JN Philoppes, MA Khedr, MHA Hassan, G Kamel, PF Lamie Bioorganic Chemistry 100, 103944, 2020 | 30 | 2020 |
| 2-Thiopyrimidine/chalcone hybrids: design, synthesis, ADMET prediction, and anticancer evaluation as STAT3/STAT5a inhibitors PF Lamie, JN Philoppes Journal of enzyme inhibition and medicinal chemistry 35 (1), 864-879, 2020 | 27 | 2020 |
| Design, synthesis, and biological evaluation of novel 1,2‐diaryl‐4‐substituted‐benzylidene‐5(4H)‐imidazolone derivatives as cytotoxic agents and COX‐2/LOX … PF Lamie, JN Philoppes, L Rárová Archiv der Pharmazie 351 (3-4), 1700311, 2018 | 20 | 2018 |
| Design, synthesis, stereochemical determination, molecular docking study, in silico pre-ADMET prediction and anti-proliferative activities of indole-pyrimidine derivatives as … PF Lamie, JN Philoppes Bioorganic Chemistry 116, 105335, 2021 | 15 | 2021 |
| Synthesis and in vitro antitumor activity of new benzothiazole and benzoxazole derivatives MM Kandeel, EKA Abdelall, MK Abd El Hamid, MA Abdelgawad, ... Journal of chemical and pharmaceutical research 5 (8), 16-21, 2013 | 14 | 2013 |
| Design and synthesis of new indole drug candidates to treat Alzheimer’s disease and targeting neuro-inflammation using a multi-target-directed ligand (MTDL) strategy PF Lamie, MM Abdel-Fattah, JN Philoppes Journal of enzyme inhibition and medicinal chemistry 37 (1), 2660-2678, 2022 | 12 | 2022 |
| Design and synthesis of three series of novel antitumor–azo derivatives PF Lamie, JN Philoppes Medicinal Chemistry Research 26, 1228-1240, 2017 | 11 | 2017 |
| Synthesis and cytotoxic activity of new pyrazolo [1, 5-a] pyrimidines and determination of pyrimidine regiospecific ring formation with 2D NMR EKA Abdelall, JN Philoppes Ann Arbor, MI: Michigan Publishing, University of Michigan Library, 2016 | 10 | 2016 |
| Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on celecoxib scaffold supported with in vivo anti-inflammatory activity … KRA Abdellatif, EKA Abdelall, HAH Elshemy, JN Philoppes, ... Bioorganic Chemistry 120, 105627, 2022 | 9 | 2022 |
| Novel N-methylsulfonyl-indole derivatives: biological activity and COX-2/5-LOX inhibitory effect with improved gastro protective profile and reduced cardio vascular … JN Philoppes, MA Abdelgawad, MAS Abourehab, M Sebak, M A. Darwish, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 246-266, 2023 | 7 | 2023 |
| Nutritional studies on marine mollusk Pleuroploca trapezium (Gastropoda: Fasciolariidae) from Tuticorin coastal waters TP Anand, C Chellaram, M Chandrika, CG Rajamalar, AN Parveen, ... Journal of Chemical and Pharmaceutical Research 5 (4), 16-21, 2013 | 7 | 2013 |
| Development of safe and antioxidant COX-2 inhibitors; Synthesis, molecular docking analysis and biological evaluation of novel pyrrolizine 5-carboxamides EKA Abdelall, HAH Elshemy, JN Philoppes, MM Abdel-Fattah, ... Bioorganic Chemistry 143, 107098, 2024 | | 2024 |
