An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells I Zanoni, Y Tan, M Di Gioia, A Broggi, J Ruan, J Shi, CA Donado, F Shao, ... Science 352 (6290), 1232-1236, 2016 | 534 | 2016 |
By capturing inflammatory lipids released from dying cells, the receptor CD14 induces inflammasome-dependent phagocyte hyperactivation I Zanoni, Y Tan, M Di Gioia, JR Springstead, JC Kagan Immunity 47 (4), 697-709. e3, 2017 | 205 | 2017 |
Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation M Di Gioia, R Spreafico, JR Springstead, MM Mendelson, R Joehanes, ... Nature immunology 21 (1), 42-53, 2020 | 140 | 2020 |
Toll-like receptor co-receptors as master regulators of the immune response M Di Gioia, I Zanoni Molecular immunology 63 (2), 143-152, 2015 | 127 | 2015 |
IL-15 cis presentation is required for optimal NK cell activation in lipopolysaccharide-mediated inflammatory conditions I Zanoni, R Spreafico, C Bodio, M Di Gioia, C Cigni, A Broggi, T Gorletta, ... Cell reports 4 (6), 1235-1249, 2013 | 110 | 2013 |
An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity F Borriello, V Poli, E Shrock, R Spreafico, X Liu, N Pishesha, C Carpenet, ... Cell 185 (4), 614-629. e21, 2022 | 59 | 2022 |
Prioritized mass spectrometry increases the depth, sensitivity and data completeness of single-cell proteomics RG Huffman, A Leduc, C Wichmann, M Di Gioia, F Borriello, H Specht, ... Nature methods 20 (5), 714-722, 2023 | 51 | 2023 |
CD14 and NFAT mediate lipopolysaccharide-induced skin edema formation in mice I Zanoni, R Ostuni, S Barresi, M Di Gioia, A Broggi, B Costa, R Marzi, ... The Journal of clinical investigation 122 (5), 1747-1757, 2012 | 48 | 2012 |
Prolonged contact with dendritic cells turns lymph node‐resident NK cells into anti‐tumor effectors F Mingozzi, R Spreafico, T Gorletta, C Cigni, M Di Gioia, M Caccia, ... EMBO molecular medicine 8 (9), 1039-1051, 2016 | 40 | 2016 |
Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation V Poli, VPY Ma, M Di Gioia, A Broggi, M Benamar, Q Chen, R Mazitschek, ... Iscience 24 (11), 2021 | 30 | 2021 |
Dooming Phagocyte Responses: Inflammatory Effects of Endogenous Oxidized Phospholipids M Di Gioia, I Zanoni Frontiers in Endocrinology 12, 2021 | 26 | 2021 |
Inositol 1,4,5-trisphosphate 3-kinase B promotes Ca2+ mobilization and the inflammatory activity of dendritic cells L Marongiu, F Mingozzi, C Cigni, R Marzi, M Di Gioia, M Garrè, ... Science signaling 14 (676), eaaz2120, 2021 | 21 | 2021 |
Inhibition of transcription factor NFAT activity in activated platelets enhances their aggregation and exacerbates gram-negative bacterial septicemia V Poli, M Di Gioia, M Sola-Visner, F Granucci, AL Frelinger, AD Michelson, ... Immunity 55 (2), 224-236. e5, 2022 | 19 | 2022 |
Prioritized single-cell proteomics reveals molecular and functional polarization across primary macrophages RG Huffman, A Leduc, C Wichmann, M di Gioia, F Borriello, H Specht, ... BioRxiv, 2022.03. 16.484655, 2022 | 14 | 2022 |
CD14: Not Just Chaperone, But a Key-Player in Inflammation M Di Gioia, I Zanoni The Role of Toll-Like Receptor 4 in Infectious and Non Infectious …, 2021 | 5 | 2021 |
Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter M Di Gioia, V Poli, PJ Tan, R Spreafico, A Chu, AG Cuenca, PLSM Gordts, ... bioRxiv, 2023 | 3 | 2023 |
Quantitative cytofluorimetric analysis of mouse neutrophil extracellular traps V Poli, M Di Gioia, I Zanoni STAR protocols 4 (3), 102372, 2023 | 2 | 2023 |
Homodimeric Granzyme A Opsonizes Mycobacterium tuberculosis and Inhibits Its Intracellular Growth in Human Monocytes via Toll-Like Receptor 4 and CD14 V Rasi, KR Phelps, KR Paulson, CS Eickhoff, M Chinnaraj, N Pozzi, ... The Journal of Infectious Diseases 229 (3), 876-887, 2024 | 1 | 2024 |
Aged vasculature drives neutrophils mad M Di Gioia, I Zanoni Immunity 54 (7), 1369-1371, 2021 | 1 | 2021 |
Choreography and molecular strategy of dendritic cell-mediated NK cell activation in lipopolysaccharide-mediated inflammatory conditions I Zanoni, R Spreafico, C Bodio, T Gorletta, M Di Gioia, C Cigni, A Broggi, ... EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 43, 34-34, 2013 | | 2013 |