| Aseptic loosening of total joint replacements: mechanisms underlying osteolysis and potential therapies Y Abu-Amer, I Darwech, JC Clohisy Arthritis research & therapy 9, 1-7, 2007 | 677 | 2007 |
| Tumor necrosis factor-α (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways YH Zhang, A Heulsmann, MM Tondravi, A Mukherjee, Y Abu-Amer Journal of Biological Chemistry 276 (1), 563-568, 2001 | 651 | 2001 |
| Tumor necrosis factor-α mediates orthopedic implant osteolysis KD Merkel, JM Erdmann, KP McHugh, Y Abu-Amer, FP Ross, ... The American journal of pathology 154 (1), 203-210, 1999 | 495 | 1999 |
| NF-κB signaling and bone resorption Y Abu-Amer Osteoporosis International 24, 2377-2386, 2013 | 356 | 2013 |
| Lipopolysaccharide-stimulated osteoclastogenesis is mediated by tumor necrosis factor via its P55 receptor. Y Abu-Amer, FP Ross, J Edwards, SL Teitelbaum The Journal of clinical investigation 100 (6), 1557-1565, 1997 | 347 | 1997 |
| The IκB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis S Dai, T Hirayama, S Abbas, Y Abu-Amer Journal of Biological Chemistry 279 (36), 37219-37222, 2004 | 249 | 2004 |
| Tumor necrosis factor receptors types 1 and 2 differentially regulate osteoclastogenesis Y Abu-Amer, J Erdmann, L Alexopoulou, G Kollias, FP Ross, ... Journal of Biological Chemistry 275 (35), 27307-27310, 2000 | 245 | 2000 |
| Inflammation and epigenetic regulation in osteoarthritis J Shen, Y Abu-Amer, RJ O’keefe, A McAlinden Connective tissue research 58 (1), 49-63, 2017 | 243 | 2017 |
| IL-4 abrogates osteoclastogenesis through STAT6-dependent inhibition of NF-κB Y Abu-Amer The Journal of clinical investigation 107 (11), 1375-1385, 2001 | 239 | 2001 |
| LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis M Arra, G Swarnkar, K Ke, JE Otero, J Ying, X Duan, T Maruyama, MF Rai, ... Nature communications 11 (1), 3427, 2020 | 236 | 2020 |
| Marrow stromal cells and osteoclast precursors differentially contribute to TNF-α-induced osteoclastogenesis in vivo H Kitaura, MS Sands, K Aya, P Zhou, T Hirayama, B Uthgenannt, S Wei, ... The Journal of Immunology 173 (8), 4838-4846, 2004 | 217 | 2004 |
| Cutting edge: IL-4-mediated protection of primary B lymphocytes from apoptosis via Stat6-dependent regulation of glycolytic metabolism FJ Dufort, BF Bleiman, MR Gumina, D Blair, DJ Wagner, MF Roberts, ... The Journal of Immunology 179 (8), 4953-4957, 2007 | 202 | 2007 |
| Tumor necrosis factor-α activation of nuclear transcription factor-κB in marrow macrophages is mediated by c-Src tyrosine phosphorylation of IκBα Y Abu-Amer, FP Ross, KP McHugh, A Livolsi, JF Peyron, SL Teitelbaum Journal of Biological Chemistry 273 (45), 29417-29423, 1998 | 183 | 1998 |
| Activation of peroxisome proliferator-activated receptor-γ pathway inhibits osteoclast differentiation G Mbalaviele, Y Abu-Amer, A Meng, R Jaiswal, S Beck, MF Pittenger, ... Journal of Biological Chemistry 275 (19), 14388-14393, 2000 | 167 | 2000 |
| Tumor necrosis factor-α inhibits pre-osteoblast differentiation through its type-1 receptor S Abbas, YH Zhang, JC Clohisy, Y Abu-Amer Cytokine 22 (1-2), 33-41, 2003 | 165 | 2003 |
| NF‐kB signaling blockade abolishes implant particle‐induced osteoclastogenesis JC Clohisy, T Hirayama, E Frazier, SK Han, Y Abu‐Amer Journal of Orthopaedic Research 22 (1), 13-20, 2004 | 147 | 2004 |
| NLRP3 inflammasome activation triggers gasdermin D–independent inflammation C Wang, T Yang, J Xiao, C Xu, Y Alippe, K Sun, TD Kanneganti, ... Science immunology 6 (64), eabj3859, 2021 | 146 | 2021 |
| Targeting the NF-κB signaling pathway in chronic tendon disease AC Abraham, SA Shah, M Golman, L Song, X Li, I Kurtaliaj, M Akbar, ... Science translational medicine 11 (481), eaav4319, 2019 | 136 | 2019 |
| Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice J Xiao, C Wang, JC Yao, Y Alippe, C Xu, D Kress, R Civitelli, Y Abu-Amer, ... PLoS biology 16 (11), e3000047, 2018 | 132 | 2018 |
| Resistin induces expression of proinflammatory cytokines and chemokines in human articular chondrocytes via transcription and messenger RNA stabilization Z Zhang, X Xing, G Hensley, LW Chang, W Liao, Y Abu‐Amer, LJ Sandell Arthritis & Rheumatism 62 (7), 1993-2003, 2010 | 128 | 2010 |
