Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism WY Fu, Y Chen, M Sahin, XS Zhao, L Shi, JB Bikoff, KO Lai, WH Yung, ... Nature neuroscience 10 (1), 67-76, 2007 | 366 | 2007 |
Synapse development and plasticity: roles of ephrin/Eph receptor signaling KO Lai, NY Ip Current opinion in neurobiology 19 (3), 275-283, 2009 | 216 | 2009 |
Cloning and expression of a novel neurotrophin, NT-7, from carp KO Lai, WY Fu, FCF Ip, NY Ip Molecular and Cellular Neuroscience 11 (1-2), 64-76, 1998 | 215 | 1998 |
APCCdh1 mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity AKY Fu, KW Hung, WY Fu, C Shen, Y Chen, J Xia, KO Lai, NY Ip Nature neuroscience 14 (2), 181-189, 2011 | 213 | 2011 |
Structural plasticity of dendritic spines: the underlying mechanisms and its dysregulation in brain disorders KO Lai, NY Ip Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (12 …, 2013 | 212 | 2013 |
TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory KO Lai, ASL Wong, MC Cheung, P Xu, Z Liang, KC Lok, H Xie, ME Palko, ... Nature neuroscience 15 (11), 1506-1515, 2012 | 182 | 2012 |
Tyk2/STAT3 signaling mediates β-amyloid-induced neuronal cell death: implications in Alzheimer's disease J Wan, AKY Fu, FCF Ip, HK Ng, J Hugon, G Page, JH Wang, KO Lai, Z Wu, ... Journal of neuroscience 30 (20), 6873-6881, 2010 | 153 | 2010 |
Importin-mediated retrograde transport of CREB2 from distal processes to the nucleus in neurons KO Lai, Y Zhao, TH Ch'ng, KC Martin Proceedings of the National Academy of Sciences 105 (44), 17175-17180, 2008 | 117 | 2008 |
Recent advances in understanding the roles of Cdk5 in synaptic plasticity KO Lai, NY Ip Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1792 (8), 741-745, 2009 | 108 | 2009 |
Identification of the Jak/Stat proteins as novel downstream targets of EphA4 signaling in muscle: implications in the regulation of acetylcholinesterase expression KO Lai, Y Chen, HM Po, KC Lok, K Gong, NY Ip Journal of Biological Chemistry 279 (14), 13383-13392, 2004 | 105 | 2004 |
Familial Alzheimer’s disease–associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+ entry BCK Tong, CSK Lee, WH Cheng, KO Lai, J Kevin Foskett, KH Cheung Science signaling 9 (444), ra89-ra89, 2016 | 104 | 2016 |
Expression of Eph receptors in skeletal muscle and their localization at the neuromuscular junction KO Lai, FCF Ip, J Cheung, AKY Fu, NY Ip Molecular and Cellular Neuroscience 17 (6), 1034-1047, 2001 | 85 | 2001 |
Cloning and characterization of muscle-specific kinase in chicken FCF Ip, DG Glass, DR Gies, J Cheung, KO Lai, AKY Fu, GD Yancopoulos, ... Molecular and Cellular Neuroscience 16 (5), 661-673, 2000 | 68 | 2000 |
Ephrin-B1 reverse signaling activates JNK through a novel mechanism that is independent of tyrosine phosphorylation Z Xu, KO Lai, HM Zhou, SC Lin, NY Ip Journal of Biological Chemistry 278 (27), 24767-24775, 2003 | 66 | 2003 |
α-Syntrophin regulates ARMS localization at the neuromuscular junction and enhances EphA4 signaling in an ARMS-dependent manner S Luo, Y Chen, KO Lai, JC Arévalo, SC Froehner, ME Adams, MV Chao, ... The Journal of cell biology 169 (5), 813-824, 2005 | 56 | 2005 |
Central synapse and neuromuscular junction: same players, different roles KO Lai, NY Ip TRENDS in Genetics 19 (7), 395-402, 2003 | 55 | 2003 |
Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory J Zhao, AHK Fok, R Fan, PY Kwan, HL Chan, LHY Lo, YS Chan, ... elife 9, e53456, 2020 | 50 | 2020 |
The pseudokinase CaMKv is required for the activity-dependent maintenance of dendritic spines Z Liang, Y Zhan, Y Shen, CCL Wong, JR Yates III, F Plattner, KO Lai, ... Nature communications 7 (1), 13282, 2016 | 45 | 2016 |
Muscle-derived neurotrophin-3 increases the aggregation of acetylcholine receptors in neuron–muscle co-cultures AKY Fu, FCF Ip, KO Lai, KWK Tsim, NY Ip Neuroreport 8 (18), 3895-3900, 1997 | 42 | 1997 |
Cdk5 regulates activity-dependent gene expression and dendrite development Z Liang, T Ye, X Zhou, KO Lai, AKY Fu, NY Ip Journal of Neuroscience 35 (45), 15127-15134, 2015 | 37 | 2015 |