Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase M Hetman, K Kanning, JE Cavanaugh, Z Xia Journal of Biological Chemistry 274 (32), 22569-22580, 1999 | 676 | 1999 |
Role of glycogen synthase kinase-3β in neuronal apoptosis induced by trophic withdrawal M Hetman, JE Cavanaugh, D Kimelman, Z Xia Journal of Neuroscience 20 (7), 2567-2574, 2000 | 565 | 2000 |
P38 MAP kinase mediates BAX translocation in nitric oxide–induced apoptosis in neurons S Ghatan, S Larner, Y Kinoshita, M Hetman, L Patel, Z Xia, RJ Youle, ... The Journal of cell biology 150 (2), 335-348, 2000 | 516 | 2000 |
Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells. P Saftig, M Hetman, W Schmahl, K Weber, L Heine, H Mossmann, ... The EMBO journal 14 (15), 3599-3608, 1995 | 505 | 1995 |
Role of extracellular signal regulated kinases 1 and 2 in neuronal survival M Hetman, A Gozdz European journal of biochemistry 271 (11), 2050-2055, 2004 | 344 | 2004 |
Differential regulation of mitogen-activated protein kinases ERK1/2 and ERK5 by neurotrophins, neuronal activity, and cAMP in neurons JE Cavanaugh, J Ham, M Hetman, S Poser, C Yan, Z Xia Journal of Neuroscience 21 (2), 434-443, 2001 | 256 | 2001 |
Ciliary neurotrophic factor mediates dopamine D2 receptor-induced CNS neurogenesis in adult mice P Yang, SA Arnold, A Habas, M Hetman, T Hagg Journal of Neuroscience 28 (9), 2231-2241, 2008 | 195 | 2008 |
Survival signaling pathways activated by NMDA receptors M Hetman, G Kharebava Current topics in medicinal chemistry 6 (8), 787-799, 2006 | 189 | 2006 |
DNA fragmentation in rat brain after intraperitoneal administration of kainate RK Filipkowski, M Hetman, B Kaminska, L Kaczmarek Neuroreport 5 (12), 1538-1540, 1994 | 169 | 1994 |
Epigenetic silencing of nucleolar rRNA genes in Alzheimer's disease M Pietrzak, G Rempala, PT Nelson, JJ Zheng, M Hetman PloS one 6 (7), e22585, 2011 | 165 | 2011 |
Emerging roles of the neuronal nucleolus M Hetman, M Pietrzak Trends in neurosciences 35 (5), 305-314, 2012 | 154 | 2012 |
Signaling pathways mediating anti-apoptotic action of neurotrophins M Hetman, Z Xia Acta neurobiologiae experimentalis 60 (4), 531-545, 2000 | 137 | 2000 |
Attenuating the endoplasmic reticulum stress response improves functional recovery after spinal cord injury SS Ohri, MA Maddie, Y Zhao, MS Qiu, M Hetman, SR Whittemore Glia 59 (10), 1489-1502, 2011 | 131 | 2011 |
ERK1/2 antagonizes glycogen synthase kinase-3β-induced apoptosis in cortical neurons M Hetman, SL Hsuan, A Habas, MJ Higgins, Z Xia Journal of Biological Chemistry 277 (51), 49577-49584, 2002 | 109 | 2002 |
Role of megakaryoblastic acute leukemia-1 in ERK1/2-dependent stimulation of serum response factor-driven transcription by BDNF or increased synaptic activity K Kalita, G Kharebava, JJ Zheng, M Hetman Journal of Neuroscience 26 (39), 10020-10032, 2006 | 105 | 2006 |
Inhibition of nucleolar transcription as a trigger for neuronal apoptosis K Kalita, D Makonchuk, C Gomes, JJ Zheng, M Hetman Journal of neurochemistry 105 (6), 2286-2299, 2008 | 99 | 2008 |
A positive feedback loop between glycogen synthase kinase 3β and protein phosphatase 1 after stimulation of NR2B NMDA receptors in forebrain neurons E Szatmari, A Habas, P Yang, JJ Zheng, T Hagg, M Hetman Journal of Biological Chemistry 280 (45), 37526-37535, 2005 | 99 | 2005 |
Neuronal excitation-driven and AP-1-dependent activation of tissue inhibitor of metalloproteinases-1 gene expression in rodent hippocampus J Jaworski, IW Biedermann, J Lapinska, A Szklarczyk, I Figiel, D Konopka, ... Journal of Biological Chemistry 274 (40), 28106-28112, 1999 | 96 | 1999 |
Taxol induces apoptosis in cortical neurons by a mechanism independent of Bcl-2 phosphorylation XA Figueroa-Masot, M Hetman, MJ Higgins, N Kokot, Z Xia Journal of Neuroscience 21 (13), 4657-4667, 2001 | 93 | 2001 |
Ribosomal biogenesis as an emerging target of neurodevelopmental pathologies M Hetman, LP Slomnicki Journal of neurochemistry 148 (3), 325-347, 2019 | 91 | 2019 |